Acknowledgments

Many thanks to Amos BAIROCH for his help in the development of the ACUTS compilation. Many of the information relative to gene function and included in ACUTS come from the SWISS-PROT database.

Many thanks to Philipp BUCHER for his valuable comments and to Manuel PEITSCH for his support.

This work was done thanks to computer facilities provided by the Geneva Biomedical Research Institute (Glaxo-Wellcome Research & Development SA) and by the CHEMPUTEAM SA company (Geneva).