(data stored in SCRATCH zone)

SWISSPROT: A0A0E1NNJ6_YERPA

ID   A0A0E1NNJ6_YERPA        Unreviewed;       426 AA.
AC   A0A0E1NNJ6;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   05-DEC-2018, entry version 27.
DE   RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369, ECO:0000256|RuleBase:RU003370};
GN   OrderedLocusNames=YPA_0586 {ECO:0000313|EMBL:ABG12554.1};
OS   Yersinia pestis bv. Antiqua (strain Antiqua).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=360102 {ECO:0000313|EMBL:ABG12554.1, ECO:0000313|Proteomes:UP000001971};
RN   [1] {ECO:0000313|EMBL:ABG12554.1, ECO:0000313|Proteomes:UP000001971}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Antiqua {ECO:0000313|EMBL:ABG12554.1,
RC   ECO:0000313|Proteomes:UP000001971};
RX   PubMed=16740952; DOI=10.1128/JB.00124-06;
RA   Chain P.S., Hu P., Malfatti S.A., Radnedge L., Larimer F.,
RA   Vergez L.M., Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and
RT   Nepal516: evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC         Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57288; EC=2.3.3.16;
CC         Evidence={ECO:0000256|RuleBase:RU003370};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       isocitrate from oxaloacetate: step 1/2.
CC       {ECO:0000256|RuleBase:RU003370}.
CC   -!- SIMILARITY: Belongs to the citrate synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001369, ECO:0000256|RuleBase:RU003406}.
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DR   EMBL; CP000308; ABG12554.1; -; Genomic_DNA.
DR   RefSeq; WP_002210721.1; NZ_CP009906.1.
DR   EnsemblBacteria; ABG12554; ABG12554; YPA_0586.
DR   EnsemblBacteria; AJJ78524; AJJ78524; CH58_3444.
DR   KEGG; ypa:YPA_0586; -.
DR   PATRIC; fig|360102.15.peg.3612; -.
DR   KO; K01647; -.
DR   OMA; TVGWCAQ; -.
DR   UniPathway; UPA00223; UER00717.
DR   Proteomes; UP000001971; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0004108; F:citrate (Si)-synthase activity; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.230.10; -; 1.
DR   Gene3D; 1.10.580.10; -; 1.
DR   InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR   InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR   InterPro; IPR002020; Citrate_synthase.
DR   InterPro; IPR019810; Citrate_synthase_AS.
DR   InterPro; IPR024176; Citrate_synthase_bac-typ.
DR   InterPro; IPR036969; Citrate_synthase_sf.
DR   InterPro; IPR010953; Citrate_synthase_typ-I.
DR   Pfam; PF00285; Citrate_synt; 1.
DR   PIRSF; PIRSF001369; Citrate_synth; 1.
DR   PRINTS; PR00143; CITRTSNTHASE.
DR   SUPFAM; SSF48256; SSF48256; 1.
DR   TIGRFAMs; TIGR01798; cit_synth_I; 1.
DR   PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0E1NNJ6.
DR   SWISS-2DPAGE; A0A0E1NNJ6.
KW   Acyltransferase {ECO:0000313|EMBL:ABG12554.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001971};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001369,
KW   ECO:0000256|RuleBase:RU003370, ECO:0000313|EMBL:ABG12554.1};
KW   Tricarboxylic acid cycle {ECO:0000256|RuleBase:RU003370}.
SQ   SEQUENCE   426 AA;  47979 MW;  8A0D1E83C9D29AD3 CRC64;
     MADKKATLNL GEAAIELGVL SPTLGTDVID VRTLGSKGYF TFDPGFTSTA SCESKITYID
     GDQGILLHRG FPIAQLAKDS TYLEVCYILL YGETPTPEEY KTFKTTVTRH TMIHEQITRL
     FHGFRRDSHP MAVLCGVTGA LAAFYHDALD VNNERHREIT AFRLLSKMPT VAAMCYKYSL
     GQPFVYPRND LSYAGNFLHM MFSTPCEKYE VNPVLERAMD RILILHADHE QNASTSTVRT
     AGSSGANPFA CIAAGIASLW GPAHGGANEA CLKMLEEIKT VEHIPEFIRR AKDKNDSFRL
     MGFGHRVYKN YDPRATVMRE TCHEVLEELK LNNSLLEVAM ELENIALNDP YFIEKKLYPN
     VDFYSGIILK AMGIPSSMFT VIFAIARTIG WIAHWNEMHN DGIKIARPRQ LYTGYTERDF
     QSQLKK
//

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