(data stored in SCRATCH zone)

SWISSPROT: A0A0E1NWH9_YERPA

ID   A0A0E1NWH9_YERPA        Unreviewed;       435 AA.
AC   A0A0E1NWH9;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   16-JAN-2019, entry version 26.
DE   SubName: Full=Isocitrate lyase {ECO:0000313|EMBL:ABG11987.1};
DE            EC=4.1.3.1 {ECO:0000313|EMBL:ABG11987.1};
GN   OrderedLocusNames=YPA_0018 {ECO:0000313|EMBL:ABG11987.1};
OS   Yersinia pestis bv. Antiqua (strain Antiqua).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=360102 {ECO:0000313|EMBL:ABG11987.1, ECO:0000313|Proteomes:UP000001971};
RN   [1] {ECO:0000313|EMBL:ABG11987.1, ECO:0000313|Proteomes:UP000001971}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Antiqua {ECO:0000313|EMBL:ABG11987.1,
RC   ECO:0000313|Proteomes:UP000001971};
RX   PubMed=16740952; DOI=10.1128/JB.00124-06;
RA   Chain P.S., Hu P., Malfatti S.A., Radnedge L., Larimer F.,
RA   Vergez L.M., Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and
RT   Nepal516: evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|PIRSR:PIRSR001362-3};
CC       Note=Can also use Mn(2+) ion. {ECO:0000256|PIRSR:PIRSR001362-3};
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DR   EMBL; CP000308; ABG11987.1; -; Genomic_DNA.
DR   RefSeq; WP_002212078.1; NZ_CP009906.1.
DR   SMR; A0A0E1NWH9; -.
DR   EnsemblBacteria; ABG11987; ABG11987; YPA_0018.
DR   EnsemblBacteria; AJJ81314; AJJ81314; CH58_2851.
DR   KEGG; ypa:YPA_0018; -.
DR   PATRIC; fig|360102.15.peg.3006; -.
DR   KO; K01637; -.
DR   OMA; LEKDWAE; -.
DR   Proteomes; UP000001971; Chromosome.
DR   GO; GO:0004451; F:isocitrate lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   CDD; cd00377; ICL_PEPM; 1.
DR   Gene3D; 3.20.20.60; -; 1.
DR   InterPro; IPR039556; ICL/PEPM.
DR   InterPro; IPR006254; Isocitrate_lyase.
DR   InterPro; IPR018523; Isocitrate_lyase_ph_CS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   PANTHER; PTHR21631; PTHR21631; 1.
DR   Pfam; PF00463; ICL; 2.
DR   PIRSF; PIRSF001362; Isocit_lyase; 1.
DR   SUPFAM; SSF51621; SSF51621; 1.
DR   TIGRFAMs; TIGR01346; isocit_lyase; 2.
DR   PROSITE; PS00161; ISOCITRATE_LYASE; 1.
PE   4: Predicted;
DR   PRODOM; A0A0E1NWH9.
DR   SWISS-2DPAGE; A0A0E1NWH9.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001971};
KW   Lyase {ECO:0000313|EMBL:ABG11987.1};
KW   Magnesium {ECO:0000256|PIRSR:PIRSR001362-3};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR001362-3}.
FT   ACT_SITE    196    196       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR001362-1}.
FT   METAL       158    158       Magnesium. {ECO:0000256|PIRSR:
FT                                PIRSR001362-3}.
SQ   SEQUENCE   435 AA;  47672 MW;  976D6648820330B1 CRC64;
     MTISRTQQIQ QLEQEWTSPR WKNITRPYSA EDVIKLRGSV NPECTFAQNG AKKLWELLHG
     GSRKGYINCL GALTGGQALQ QAKAGVEAIY MSGWQVAADA NTASSMYPDQ SLYPVDSVPA
     VVKRINNSFR RADQIQWSNN IEPGSKGYTD YFLPIVADAE AGFGGVLNAF ELMKAMIEAG
     AAGVHFEDQL AAVKKCGHMG GKVLVPTQEA IQKLVAARLA ADVLGVPTLL IARTDADAAD
     LLTSDCDPYD REFITGDRTA EGFFRTRAGI EQAISRGLAY APYADLVWCE TSTPDLALAK
     RFADAVHAQF PGKLLAYNCS PSFNWKKNLT DQQIASFQDE LSAMGYKYQF ITLAGIHSMW
     FNMFDLAHAY AQGEGMKHYV EKVQQPEFAS VDRGYTFASH QQEVGTGYFD KVTNIIQGGA
     SSVTALTGST EEQQF
//

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