(data stored in SCRATCH zone)

SWISSPROT: A0A0F6BHI6_GEOS0

ID   A0A0F6BHI6_GEOS0        Unreviewed;       292 AA.
AC   A0A0F6BHI6;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   08-MAY-2019, entry version 19.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase I {ECO:0000256|HAMAP-Rule:MF_01877};
DE            EC=2.1.1.198 {ECO:0000256|HAMAP-Rule:MF_01877};
DE   AltName: Full=16S rRNA 2'-O-ribose C1402 methyltransferase {ECO:0000256|HAMAP-Rule:MF_01877};
DE   AltName: Full=rRNA (cytidine-2'-O-)-methyltransferase RsmI {ECO:0000256|HAMAP-Rule:MF_01877};
GN   Name=rsmI {ECO:0000256|HAMAP-Rule:MF_01877};
GN   OrderedLocusNames=GY4MC1_0031 {ECO:0000313|EMBL:ADP72887.1};
OS   Geobacillus sp. (strain Y4.1MC1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=581103 {ECO:0000313|EMBL:ADP72887.1, ECO:0000313|Proteomes:UP000002034};
RN   [1] {ECO:0000313|EMBL:ADP72887.1, ECO:0000313|Proteomes:UP000002034}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y4.1MC1 {ECO:0000313|EMBL:ADP72887.1,
RC   ECO:0000313|Proteomes:UP000002034};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Zhang X., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N.,
RA   Ovchinnikova G., Brumm P., Mead D., Woyke T.;
RT   "Complete sequence of chromosome of Geobacillus sp. Y4.1MC1.";
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the 2'-O-methylation of the ribose of cytidine
CC       1402 (C1402) in 16S rRNA. {ECO:0000256|HAMAP-Rule:MF_01877}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine =
CC         2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:42924, Rhea:RHEA-COMP:10285,
CC         Rhea:RHEA-COMP:10286, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:74495, ChEBI:CHEBI:82748;
CC         EC=2.1.1.198; Evidence={ECO:0000256|HAMAP-Rule:MF_01877};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01877}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmI
CC       family. {ECO:0000256|HAMAP-Rule:MF_01877}.
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DR   EMBL; CP002293; ADP72887.1; -; Genomic_DNA.
DR   RefSeq; WP_013399803.1; NC_014650.1.
DR   EnsemblBacteria; ADP72887; ADP72887; GY4MC1_0031.
DR   KEGG; gmc:GY4MC1_0031; -.
DR   KO; K07056; -.
DR   OMA; RTMVFFE; -.
DR   OrthoDB; 1059309at2; -.
DR   BioCyc; GSP581103:G1GOQ-43-MONOMER; -.
DR   Proteomes; UP000002034; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0070677; F:rRNA (cytosine-2'-O-)-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000453; P:enzyme-directed rRNA 2'-O-methylation; IEA:UniProtKB-UniRule.
DR   CDD; cd11648; RsmI; 1.
DR   Gene3D; 3.30.950.10; -; 1.
DR   Gene3D; 3.40.1010.10; -; 1.
DR   HAMAP; MF_01877; 16SrRNA_methyltr_I; 1.
DR   InterPro; IPR000878; 4pyrrol_Mease.
DR   InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR   InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR   InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR   InterPro; IPR008189; rRNA_ssu_MeTfrase_I.
DR   InterPro; IPR018063; SAM_MeTrfase_RsmI_CS.
DR   PANTHER; PTHR46111; PTHR46111; 1.
DR   Pfam; PF00590; TP_methylase; 1.
DR   PIRSF; PIRSF005917; MTase_YraL; 1.
DR   SUPFAM; SSF53790; SSF53790; 1.
DR   TIGRFAMs; TIGR00096; TIGR00096; 1.
DR   PROSITE; PS01296; RSMI; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0F6BHI6.
DR   SWISS-2DPAGE; A0A0F6BHI6.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002034};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01877};
KW   Methyltransferase {ECO:0000256|HAMAP-Rule:MF_01877,
KW   ECO:0000313|EMBL:ADP72887.1};
KW   rRNA processing {ECO:0000256|HAMAP-Rule:MF_01877};
KW   S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_01877};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_01877,
KW   ECO:0000313|EMBL:ADP72887.1}.
FT   DOMAIN       15    214       TP_methylase. {ECO:0000259|Pfam:PF00590}.
FT   COILED      144    167       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   292 AA;  34056 MW;  0A050E788A4B6FAA CRC64;
     MLWQQKSFED NHKGTLYIVP TPIGNLEDMT FRAVRILQEV DMIAAEDTRQ TKKLLNHFQI
     RTPLISYHEH NKYTSGPQIV ERLKAGESVA LVSDAGMPGI SDPGHELVVS ALEERCPVVP
     LPGANAALTA LVASGLSTNH FYFFGFLERT KKEKKEQLES LKKIRETMIF YEAPHRMQET
     LMMMHEVFGE RRVVLCRELT KRFEEFIRGN LSEIVEWVSI HEIRGEFCIV VEGAKETQED
     EKTEAWWHSL TPVEHVEYYI REKNFTTKEA IKQTAKDRNM SKREVYRQYH RQ
//

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