(data stored in SCRATCH zone)

SWISSPROT: A0A0F6BHT8_GEOS0

ID   A0A0F6BHT8_GEOS0        Unreviewed;        72 AA.
AC   A0A0F6BHT8;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   08-MAY-2019, entry version 23.
DE   RecName: Full=Translation initiation factor IF-1 {ECO:0000256|HAMAP-Rule:MF_00075};
GN   Name=infA {ECO:0000256|HAMAP-Rule:MF_00075};
GN   OrderedLocusNames=GY4MC1_0133 {ECO:0000313|EMBL:ADP72989.1};
OS   Geobacillus sp. (strain Y4.1MC1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=581103 {ECO:0000313|EMBL:ADP72989.1, ECO:0000313|Proteomes:UP000002034};
RN   [1] {ECO:0000313|EMBL:ADP72989.1, ECO:0000313|Proteomes:UP000002034}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y4.1MC1 {ECO:0000313|EMBL:ADP72989.1,
RC   ECO:0000313|Proteomes:UP000002034};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Zhang X., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N.,
RA   Ovchinnikova G., Brumm P., Mead D., Woyke T.;
RT   "Complete sequence of chromosome of Geobacillus sp. Y4.1MC1.";
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: One of the essential components for the initiation of
CC       protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the
CC       30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently
CC       binds. Helps modulate mRNA selection, yielding the 30S pre-
CC       initiation complex (PIC). Upon addition of the 50S ribosomal
CC       subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S
CC       translation initiation complex. {ECO:0000256|HAMAP-Rule:MF_00075,
CC       ECO:0000256|SAAS:SAAS01025698}.
CC   -!- SUBUNIT: Component of the 30S ribosomal translation pre-initiation
CC       complex which assembles on the 30S ribosome in the order IF-2 and
CC       IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can
CC       occur at any time during PIC assembly. {ECO:0000256|HAMAP-
CC       Rule:MF_00075, ECO:0000256|SAAS:SAAS00326798}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00075}.
CC   -!- SIMILARITY: Belongs to the IF-1 family. {ECO:0000256|HAMAP-
CC       Rule:MF_00075, ECO:0000256|SAAS:SAAS00571750}.
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DR   EMBL; CP002293; ADP72989.1; -; Genomic_DNA.
DR   RefSeq; WP_003247618.1; NC_014650.1.
DR   EnsemblBacteria; ADP72989; ADP72989; GY4MC1_0133.
DR   GeneID; 29574169; -.
DR   KEGG; gmc:GY4MC1_0133; -.
DR   KO; K02518; -.
DR   OMA; AHVSGKM; -.
DR   OrthoDB; 2066663at2; -.
DR   BioCyc; GSP581103:G1GOQ-160-MONOMER; -.
DR   Proteomes; UP000002034; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043022; F:ribosome binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd04451; S1_IF1; 1.
DR   HAMAP; MF_00075; IF_1; 1.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR006196; RNA-binding_domain_S1_IF1.
DR   InterPro; IPR022967; S1_dom.
DR   InterPro; IPR004368; TIF_IF1.
DR   PANTHER; PTHR33370; PTHR33370; 1.
DR   Pfam; PF01176; eIF-1a; 1.
DR   SMART; SM00316; S1; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   TIGRFAMs; TIGR00008; infA; 1.
DR   PROSITE; PS50832; S1_IF1_TYPE; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0F6BHT8.
DR   SWISS-2DPAGE; A0A0F6BHT8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002034};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00075};
KW   Initiation factor {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|PROSITE-ProRule:PRU00181, ECO:0000256|SAAS:SAAS00462727,
KW   ECO:0000313|EMBL:ADP72989.1};
KW   Phosphoprotein {ECO:0000256|HAMAP-Rule:MF_00075};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|PROSITE-ProRule:PRU00181, ECO:0000256|SAAS:SAAS00462770};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|SAAS:SAAS00769587};
KW   rRNA-binding {ECO:0000256|HAMAP-Rule:MF_00075,
KW   ECO:0000256|SAAS:SAAS00769595}.
FT   DOMAIN        1     72       S1-like. {ECO:0000259|PROSITE:PS50832}.
FT   MOD_RES      60     60       Phosphotyrosine. {ECO:0000256|HAMAP-Rule:
FT                                MF_00075}.
SQ   SEQUENCE   72 AA;  8228 MW;  57C0C615BBE97D8E CRC64;
     MAKDDVIEVE GTVVETLPNA MFRVELENGH TVLAHVSGKI RMHFIRILPG DKVTVELSPY
     DLTRGRITYR YK
//

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