(data stored in SCRATCH zone)

SWISSPROT: A0A0F6BHV7_GEOS0

ID   A0A0F6BHV7_GEOS0        Unreviewed;       306 AA.
AC   A0A0F6BHV7;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   08-MAY-2019, entry version 32.
DE   RecName: Full=Arginase {ECO:0000256|RuleBase:RU361159};
DE            EC=3.5.3.1 {ECO:0000256|RuleBase:RU361159};
GN   OrderedLocusNames=GY4MC1_0152 {ECO:0000313|EMBL:ADP73008.1};
OS   Geobacillus sp. (strain Y4.1MC1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=581103 {ECO:0000313|EMBL:ADP73008.1, ECO:0000313|Proteomes:UP000002034};
RN   [1] {ECO:0000313|EMBL:ADP73008.1, ECO:0000313|Proteomes:UP000002034}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Y4.1MC1 {ECO:0000313|EMBL:ADP73008.1,
RC   ECO:0000313|Proteomes:UP000002034};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Zhang X., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N.,
RA   Ovchinnikova G., Brumm P., Mead D., Woyke T.;
RT   "Complete sequence of chromosome of Geobacillus sp. Y4.1MC1.";
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + L-arginine = L-ornithine + urea;
CC         Xref=Rhea:RHEA:20569, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:32682, ChEBI:CHEBI:46911; EC=3.5.3.1;
CC         Evidence={ECO:0000256|RuleBase:RU361159};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|RuleBase:RU361159};
CC       Note=Binds 2 manganese ions per subunit.
CC       {ECO:0000256|RuleBase:RU361159};
CC   -!- SIMILARITY: Belongs to the arginase family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00742, ECO:0000256|RuleBase:RU003684}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002293; ADP73008.1; -; Genomic_DNA.
DR   RefSeq; WP_003247640.1; NC_014650.1.
DR   EnsemblBacteria; ADP73008; ADP73008; GY4MC1_0152.
DR   GeneID; 29237200; -.
DR   KEGG; gmc:GY4MC1_0152; -.
DR   KO; K01476; -.
DR   OMA; GATYREA; -.
DR   OrthoDB; 1598732at2; -.
DR   BioCyc; GSP581103:G1GOQ-191-MONOMER; -.
DR   Proteomes; UP000002034; Chromosome.
DR   GO; GO:0004053; F:arginase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd09989; Arginase; 1.
DR   InterPro; IPR014033; Arginase.
DR   InterPro; IPR006035; Ureohydrolase.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   InterPro; IPR020855; Ureohydrolase_Mn_BS.
DR   Pfam; PF00491; Arginase; 1.
DR   PIRSF; PIRSF036979; Arginase; 1.
DR   PRINTS; PR00116; ARGINASE.
DR   SUPFAM; SSF52768; SSF52768; 1.
DR   TIGRFAMs; TIGR01229; rocF_arginase; 1.
DR   PROSITE; PS01053; ARGINASE_1; 1.
DR   PROSITE; PS51409; ARGINASE_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0F6BHV7.
DR   SWISS-2DPAGE; A0A0F6BHV7.
KW   Arginine metabolism {ECO:0000256|RuleBase:RU361159};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002034};
KW   Hydrolase {ECO:0000256|RuleBase:RU003684};
KW   Manganese {ECO:0000256|RuleBase:RU361159};
KW   Metal-binding {ECO:0000256|RuleBase:RU361159}.
SQ   SEQUENCE   306 AA;  33193 MW;  7E29FB5826AFEC72 CRC64;
     MERGNSVKKV SIIGVPMDLG QTRRGVDMGP SAMRYAGIIE RLERLHYEIE DLGDVSIGKM
     EWSDDEGLRL NLRNLKAVAK TNEKLAEMVD DVVQRGRFPL VLGGDHSIAI GTLAGVAKHY
     QNLGVIWYDA HGDLNTAETS PSGNIHGMSL AVCLGLGHPY LTKIGGYSPK VKPENVVLIG
     VRSLDEGEKQ LIREKGIKVY TMHEVDRLGM AAVMEETIAY LQGRTDGVHL SLDLDGLDPH
     DAPGVGTPVI GGLTYRESHL AMEMLAEAQL ITSAEFVEVN PILDERNKTA SVAVGLMGSL
     FGEKLV
//

If you have problems or comments...

PBIL Back to PBIL home page