(data stored in SCRATCH zone)

SWISSPROT: A0A0H2ZKD3_PSEAB

ID   A0A0H2ZKD3_PSEAB        Unreviewed;       349 AA.
AC   A0A0H2ZKD3;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   08-MAY-2019, entry version 25.
DE   RecName: Full=Spermidine/putrescine import ATP-binding protein PotA {ECO:0000256|RuleBase:RU364083};
DE            EC=7.6.2.11 {ECO:0000256|RuleBase:RU364083};
GN   Name=potA {ECO:0000256|RuleBase:RU364083};
GN   OrderedLocusNames=PA14_04250 {ECO:0000313|EMBL:ABJ15289.1};
OS   Pseudomonas aeruginosa (strain UCBPP-PA14).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208963 {ECO:0000313|EMBL:ABJ15289.1, ECO:0000313|Proteomes:UP000000653};
RN   [1] {ECO:0000313|EMBL:ABJ15289.1, ECO:0000313|Proteomes:UP000000653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCBPP-PA14 {ECO:0000313|EMBL:ABJ15289.1,
RC   ECO:0000313|Proteomes:UP000000653};
RX   PubMed=17038190; DOI=10.1186/gb-2006-7-10-r90;
RA   Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S.,
RA   Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L.,
RA   Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.;
RT   "Genomic analysis reveals that Pseudomonas aeruginosa virulence is
RT   combinatorial.";
RL   Genome Biol. 7:R90.1-R90.14(2006).
CC   -!- FUNCTION: Part of the ABC transporter complex PotABCD involved in
CC       spermidine/putrescine import. Responsible for energy coupling to
CC       the transport system. {ECO:0000256|RuleBase:RU364083,
CC       ECO:0000256|SAAS:SAAS00083152}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H(2)O + polyamine-[polyamine-binding protein](Side
CC         1) = ADP + phosphate + polyamine(Side 2) + [polyamine-binding
CC         protein](Side 1).; EC=7.6.2.11;
CC         Evidence={ECO:0000256|RuleBase:RU364083,
CC         ECO:0000256|SAAS:SAAS01153263};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (PotA), two transmembrane proteins (PotB and PotC) and a solute-
CC       binding protein (PotD). {ECO:0000256|RuleBase:RU364083,
CC       ECO:0000256|SAAS:SAAS00083151}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       Spermidine/putrescine importer (TC 3.A.1.11.1) family.
CC       {ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00569590}.
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DR   EMBL; CP000438; ABJ15289.1; -; Genomic_DNA.
DR   RefSeq; WP_004364982.1; NC_008463.1.
DR   EnsemblBacteria; ABJ15289; ABJ15289; PA14_04250.
DR   KEGG; pau:PA14_04250; -.
DR   KO; K11072; -.
DR   OMA; HTTPGAQ; -.
DR   BioCyc; PAER208963:G1G74-356-MONOMER; -.
DR   Proteomes; UP000000653; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015417; F:polyamine-transporting ATPase activity; IEA:InterPro.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005893; Sp_pt_ABC_ATP-bd.
DR   InterPro; IPR013611; Transp-assoc_OB_typ2.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08402; TOBE_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50331; SSF50331; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01187; potA; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0H2ZKD3.
DR   SWISS-2DPAGE; A0A0H2ZKD3.
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00434,
KW   ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00237035,
KW   ECO:0000313|EMBL:ABJ15289.1};
KW   Cell membrane {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00458580};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000653};
KW   Membrane {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00458555};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00434,
KW   ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00452314};
KW   Translocase {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS01153264};
KW   Transport {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00237071}.
FT   DOMAIN        5    239       ABC transporter. {ECO:0000259|PROSITE:
FT                                PS50893}.
FT   NP_BIND      41     48       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00434}.
SQ   SEQUENCE   349 AA;  37954 MW;  905B57B81AB9A7D1 CRC64;
     MTSAIAIERI CMEFGTPGQG LKALDDVSLD IHANEFFTLL GPSGCGKTTL LRLIAGFEQP
     SSGSIRLYGE RMEGLPPFRR PVNTVFQSYA LFPHMSVAEN IGFGLEMQGR PRSEIDATVS
     RMLELVKLPE VGKRRADQLS GGQQQRIALA RALASRPKVL LLDESLSALD LKLRKEMQIE
     LKRLQHETGI TFIFVTHDQE EALTMSDRIA VMSKGKVLQV GTPSDIYEAP LNRAVADFIG
     ETNFLEGQAD ADGVRLADGQ RLAATTPGSG AVTLAIRPER TELAADGQLE GVLENVVYVG
     TDTVYHLNVA GQPGFRVRQQ NRDGARCPHS PGAKVRVRVP AAAIRVLAE
//

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