(data stored in SCRATCH zone)

SWISSPROT: A0A0H2ZLB4_PSEAB

ID   A0A0H2ZLB4_PSEAB        Unreviewed;      1046 AA.
AC   A0A0H2ZLB4;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   30-AUG-2017, entry version 15.
DE   RecName: Full=Efflux pump membrane transporter {ECO:0000256|RuleBase:RU364070};
GN   Name=mexB {ECO:0000313|EMBL:ABJ15393.1};
GN   OrderedLocusNames=PA14_05540 {ECO:0000313|EMBL:ABJ15393.1};
OS   Pseudomonas aeruginosa (strain UCBPP-PA14).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208963 {ECO:0000313|EMBL:ABJ15393.1, ECO:0000313|Proteomes:UP000000653};
RN   [1] {ECO:0000313|EMBL:ABJ15393.1, ECO:0000313|Proteomes:UP000000653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCBPP-PA14 {ECO:0000313|EMBL:ABJ15393.1,
RC   ECO:0000313|Proteomes:UP000000653};
RX   PubMed=17038190; DOI=10.1186/gb-2006-7-10-r90;
RA   Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S.,
RA   Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L.,
RA   Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.;
RT   "Genomic analysis reveals that Pseudomonas aeruginosa virulence is
RT   combinatorial.";
RL   Genome Biol. 7:R90.1-R90.14(2006).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU364070}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU364070}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division
CC       (RND) (TC 2.A.6) family. {ECO:0000256|RuleBase:RU364070,
CC       ECO:0000256|SAAS:SAAS00693190}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU364070}.
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DR   EMBL; CP000438; ABJ15393.1; -; Genomic_DNA.
DR   RefSeq; WP_003107312.1; NC_008463.1.
DR   ProteinModelPortal; A0A0H2ZLB4; -.
DR   SMR; A0A0H2ZLB4; -.
DR   EnsemblBacteria; ABJ15393; ABJ15393; PA14_05540.
DR   KEGG; pau:PA14_05540; -.
DR   KO; K18138; -.
DR   OMA; TKRSMEQ; -.
DR   Proteomes; UP000000653; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.2090.10; -; 1.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR004764; HAE1.
DR   PANTHER; PTHR32063; PTHR32063; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82714; SSF82714; 2.
DR   TIGRFAMs; TIGR00915; 2A0602; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0H2ZLB4.
DR   SWISS-2DPAGE; A0A0H2ZLB4.
KW   Cell inner membrane {ECO:0000256|RuleBase:RU364070};
KW   Cell membrane {ECO:0000256|RuleBase:RU364070};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000653};
KW   Membrane {ECO:0000256|RuleBase:RU364070};
KW   Transmembrane {ECO:0000256|RuleBase:RU364070};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU364070};
KW   Transport {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM     12     32       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    340    359       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    366    390       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    437    458       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    470    493       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    539    557       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    874    891       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    898    918       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    924    948       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM    969    989       Helical. {ECO:0000256|RuleBase:RU364070}.
FT   TRANSMEM   1001   1027       Helical. {ECO:0000256|RuleBase:RU364070}.
SQ   SEQUENCE   1046 AA;  112791 MW;  FF91855338868ED2 CRC64;
     MSKFFIDRPI FAWVIALVIM LAGGLSILSL PVNQYPAIAP PAIAVQVSYP GASAETVQDT
     VVQVIEQQMN GIDNLRYISS ESNSDGSMTI TVTFEQGTDP DIAQVQVQNK LQLATPLLPQ
     EVQRQGIRVT KAVKNFLMVV GVVSTDGSMT KEDLSNYIVS NIQDPLSRTK GVGDFQVFGS
     QYSMRIWLDP AKLNSYQLTP GDVSSAIQAQ NVQISSGQLG GLPAVKGQQL NATIIGKTRL
     QTAEQFENIL LKVNPDGSQV RLKDVADVGL GGQDYSINAQ FNGSPASGIA IKLATGANAL
     DTAKAIRQTI ANLEPFMPQG MKVVYPYDTT PVVSASIHEV VKTLGEAILL VFLVMYLFLQ
     NFRATLIPTI AVPVVLLGTF GVLAAFGFSI NTLTMFGMVL AIGLLVDDAI VVVENVERVM
     AEEGLSPREA ARKSMGQIQG ALVGIAMVLS AVFLPMAFFG GSTGVIYRQF SITIVSAMAL
     SVIVALILTP ALCATMLKPI EKGDHGEHKG GFFGWFNRMF LSTTHGYERG VASILKHRAP
     YLLIYVVIVA GMIWMFTRIP TAFLPDEDQG VLFAQVQTPP GSSAERTQVV VDSMREYLLE
     KESSSVSSVF TVTGFNFAGR GQSSGMAFIM LKPWEERPGG ENSVFELAKR AQMHFFSFKD
     AMVFAFAPPS VLELGNATGF DLFLQDQAGV GHEVLLQARN KFLMLAAQNP ALQRVRPNGM
     SDEPQYKLEI DDEKASALGV SLADINSTVS IAWGSSYVND FIDRGRVKRV YLQGRPDARM
     NPDDLSKWYV RNDKGEMVPF NAFATGKWEY GSPKLERYNG VPAMEILGEP APGLSSGDAM
     AAVEEIVKQL PKGVGYSWTG LSYEERLSGS QAPALYALSL LVVFLCLAAL YESWSIPFSV
     MLVVPLGVIG ALLATSMRGL SNDVFFQVGL LTTIGLSAKN AILIVEFAKE LHEQGKGIVE
     AAIEACRMRL RPIVMTSLAF ILGVVPLAIS TGAGSGSQHA IGTGVIGGMV TATVLAIFWV
     PLFYVAVSTL FKDEASKQQA SVEKGQ
//

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