(data stored in SCRATCH zone)

SWISSPROT: A0KF49_AERHH

ID   A0KF49_AERHH            Unreviewed;       618 AA.
AC   A0KF49;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 91.
DE   SubName: Full=Glutathione-regulated potassium-efflux system protein KefB {ECO:0000313|EMBL:ABK39466.1};
GN   Name=kefB {ECO:0000313|EMBL:ABK39466.1};
GN   OrderedLocusNames=AHA_0342 {ECO:0000313|EMBL:ABK39466.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 /
OS   JCM 1027 / KCTC 2358 / NCIMB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK39466.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK39466.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2
CC       (CPA2) transporter (TC 2.A.37) family.
CC       {ECO:0000256|SAAS:SAAS00568668}.
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DR   EMBL; CP000462; ABK39466.1; -; Genomic_DNA.
DR   RefSeq; WP_011704322.1; NC_008570.1.
DR   RefSeq; YP_854871.1; NC_008570.1.
DR   STRING; 380703.AHA_0342; -.
DR   EnsemblBacteria; ABK39466; ABK39466; AHA_0342.
DR   GeneID; 4489470; -.
DR   KEGG; aha:AHA_0342; -.
DR   PATRIC; fig|380703.7.peg.327; -.
DR   eggNOG; ENOG4105CKD; Bacteria.
DR   eggNOG; COG0475; LUCA.
DR   eggNOG; COG1226; LUCA.
DR   HOGENOM; HOG000179076; -.
DR   KO; K11747; -.
DR   OMA; GDSLQHG; -.
DR   BioCyc; AHYD380703:G1G7B-343-MONOMER; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR004771; K/H_exchanger.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003148; RCK_N.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
DR   Pfam; PF02254; TrkA_N; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR00932; 2a37; 1.
DR   PROSITE; PS51201; RCK_N; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0KF49.
DR   SWISS-2DPAGE; A0KF49.
KW   Antiport {ECO:0000256|SAAS:SAAS00460756};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000756};
KW   Ion transport {ECO:0000256|SAAS:SAAS01092081};
KW   Membrane {ECO:0000256|SAAS:SAAS00460792, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00460753,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00460739,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS01092095}.
FT   TRANSMEM      6     24       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     31     49       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     55     74       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     86    109       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    115    135       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    147    172       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    184    206       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    218    236       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    272    291       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    297    317       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    329    348       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    360    380       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      409    530       RCK N-terminal. {ECO:0000259|PROSITE:
FT                                PS51201}.
SQ   SEQUENCE   618 AA;  67289 MW;  460E5EECB303A1EA CRC64;
     MGHGLLFDAF IYLSAAVIAV PLAKRWGLGS VLGYLLAGII IGPFLLGLVG EQKDVMHFAE
     FGVVLMLFLV GLELRPALLW QLKGPILGTG GLQVLLTTAA LTGVAHLIGL PWQQGLAIGL
     ILALSSTAIV LQSLQERKLM QSESGRSAFA VLLFQDIAVI PILAILPLLA IAPVASSGSS
     ELAGWQHGLL VVAAISGIVL GGHYLMRPVF RAIAQSHMRE IFVAAALLLV IAIAVLMESV
     GLSPALGSFL AGVVLADSEY RHELEADIEP FKGLLLGLFF MSVGAGINFG LFAEHPLLIP
     TLVVGLMVLK WLVLMALGFA IRISPSQRWT FGLALAQGGE FAFVLFSFAA QNKVLPGDTI
     ALLTLVVALS MALTPLLLIL NDRVIQPWFD YRNQSELPQH EQPELVEHPV IIAGFGRFGQ
     IVGRLLHGHG IGTTILEQDA SQIEMLRKYG YQVFYGDASR LDLLHAAGAH KAKLLVLSIN
     DPATSLEVIE MVKKHFPHLK ILARAQDRPH AHEILRQGVG SVYRETLGSA VDLGVEALTQ
     LGFRANQAWR AGQTFKQHDN WLLREQVNYL DDEHTYINKS LQYRDILSDL LQDDQEGQER
     IHAHNWNSGL PDNDKEAI
//

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