(data stored in SCRATCH zone)

SWISSPROT: A0KF61_AERHH

ID   A0KF61_AERHH            Unreviewed;       517 AA.
AC   A0KF61;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 75.
DE   SubName: Full=Multidrug resistance protein B {ECO:0000313|EMBL:ABK39189.1};
GN   OrderedLocusNames=AHA_0354 {ECO:0000313|EMBL:ABK39189.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 /
OS   JCM 1027 / KCTC 2358 / NCIMB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK39189.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK39189.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000462; ABK39189.1; -; Genomic_DNA.
DR   RefSeq; WP_011704334.1; NC_008570.1.
DR   RefSeq; YP_854883.1; NC_008570.1.
DR   STRING; 380703.AHA_0354; -.
DR   EnsemblBacteria; ABK39189; ABK39189; AHA_0354.
DR   GeneID; 4489482; -.
DR   KEGG; aha:AHA_0354; -.
DR   PATRIC; fig|380703.7.peg.339; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000112189; -.
DR   KO; K03446; -.
DR   OMA; GNKKGWL; -.
DR   BioCyc; AHYD380703:G1G7B-355-MONOMER; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001411; Tet-R_TetB/Drug-R_transptr.
DR   PANTHER; PTHR23501; PTHR23501; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0KF61.
DR   SWISS-2DPAGE; A0KF61.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000756};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM      9     28       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     77     96       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    102    124       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    136    157       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    163    182       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    194    213       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    225    247       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    267    288       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    300    320       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    332    349       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    369    388       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    400    417       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    484    502       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       11    507       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   517 AA;  56447 MW;  49932780D8F5D613 CRC64;
     MEPIPRRNWI AVMGGLIGAF MAILDIQITN ASLKDIQGAL SATLSESSWI STSYLVAEMI
     AIPLSGWLSR GLSVRRYLLW TTGAFIVASV LCSFSWNLTS MIVFRALQGF TGGALIPMAF
     SLIVSLLPLH KRATGMALFG LCATFAPAIG PTLGGWLTEQ MSWHYIFYMN VPPGLLVMAM
     LAHGLDKKPV DWEVIKRVDL IGIVTMAVGL GLLEVVLEEG NREDWFGSSF IVRLTVISVV
     ALVFFVISQL LRRHPLVNLR LLHNPRFALA CFAYLVLGMA LMGSIYVLPL YMTQIHNYNA
     LEIGEVLMWM GLPQLLVLPL VPRLTHKIDP RYLVSFGFLV FAVSCFMNMN MSADYAGPQL
     IQSLIVRALG QPFIMVPLSL VATASLTHDE IPSSSTLLNV LRNLGGAFGI AIIATLIDND
     TRIHVSQISS TLAASSIEGQ SYLLQLAQTM MAQGSGPELA RQQAQAMLSN TISREAAIMA
     YNQVFFVMGI FLLLASGLML LLKQPAPRAA DAEPLEA
//

If you have problems or comments...

PBIL Back to PBIL home page