(data stored in SCRATCH zone)

SWISSPROT: A0KF77_AERHH

ID   A0KF77_AERHH            Unreviewed;       209 AA.
AC   A0KF77;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 74.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase D {ECO:0000256|PIRNR:PIRNR004553};
DE            EC=2.1.1.171 {ECO:0000256|PIRNR:PIRNR004553};
GN   OrderedLocusNames=AHA_0370 {ECO:0000313|EMBL:ABK39151.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 /
OS   JCM 1027 / KCTC 2358 / NCIMB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK39151.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK39151.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- FUNCTION: Specifically methylates the guanine in position 966 of
CC       16S rRNA in the assembled 30S particle.
CC       {ECO:0000256|PIRNR:PIRNR004553}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=guanosine(966) in 16S rRNA + S-adenosyl-L-methionine =
CC         H(+) + N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:23548, Rhea:RHEA-COMP:10211,
CC         Rhea:RHEA-COMP:10212, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:74269, ChEBI:CHEBI:74481;
CC         EC=2.1.1.171; Evidence={ECO:0000256|PIRNR:PIRNR004553};
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmD
CC       family. {ECO:0000256|PIRNR:PIRNR004553}.
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DR   EMBL; CP000462; ABK39151.1; -; Genomic_DNA.
DR   RefSeq; WP_011704347.1; NC_008570.1.
DR   RefSeq; YP_854899.1; NC_008570.1.
DR   STRING; 380703.AHA_0370; -.
DR   EnsemblBacteria; ABK39151; ABK39151; AHA_0370.
DR   GeneID; 4490816; -.
DR   KEGG; aha:AHA_0370; -.
DR   PATRIC; fig|380703.7.peg.356; -.
DR   eggNOG; ENOG4106H78; Bacteria.
DR   eggNOG; COG0742; LUCA.
DR   HOGENOM; HOG000050676; -.
DR   KO; K08316; -.
DR   OMA; MGAEALC; -.
DR   BioCyc; AHYD380703:G1G7B-371-MONOMER; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0052913; F:16S rRNA (guanine(966)-N(2))-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR   InterPro; IPR004398; RNA_MeTrfase_RsmD.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   PIRSF; PIRSF004553; CHP00095; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00095; TIGR00095; 1.
DR   PROSITE; PS00092; N6_MTASE; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0KF77.
DR   SWISS-2DPAGE; A0KF77.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000756};
KW   Methyltransferase {ECO:0000256|PIRNR:PIRNR004553,
KW   ECO:0000313|EMBL:ABK39151.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW   rRNA processing {ECO:0000256|PIRNR:PIRNR004553};
KW   S-adenosyl-L-methionine {ECO:0000256|PIRNR:PIRNR004553};
KW   Transferase {ECO:0000256|PIRNR:PIRNR004553,
KW   ECO:0000313|EMBL:ABK39151.1}.
SQ   SEQUENCE   209 AA;  23294 MW;  0A2F41B55F8DAEDD CRC64;
     MPRVKSSRNG PSKSPAPQGK SGFVRIISGQ WRGRKLPVRD VEGLRPTTDR VKETIFNWLA
     PHVRGTRCLD LFAGSGGLGL EALSRYAEQV TLIEMDKGAA DQIKKNLTTL GSSQGQVIQS
     DAVSWLQGPA TPFDLVFLDP PFRRELLPQV CELLEQRGWL APDALIYLER EKEMADLPLP
     ASWQLLKDKQ AGQVCYQLYL RDTKHDAAV
//

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