(data stored in SCRATCH zone)

SWISSPROT: A0KFH5_AERHH

ID   A0KFH5_AERHH            Unreviewed;       244 AA.
AC   A0KFH5;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 66.
DE   SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:ABK37538.1};
DE            EC=4.2.1.75 {ECO:0000313|EMBL:ABK37538.1};
GN   Name=hemD {ECO:0000313|EMBL:ABK37538.1};
GN   OrderedLocusNames=AHA_0468 {ECO:0000313|EMBL:ABK37538.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 /
OS   JCM 1027 / KCTC 2358 / NCIMB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK37538.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK37538.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
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DR   EMBL; CP000462; ABK37538.1; -; Genomic_DNA.
DR   RefSeq; WP_011704441.1; NC_008570.1.
DR   RefSeq; YP_855001.1; NC_008570.1.
DR   STRING; 380703.AHA_0468; -.
DR   EnsemblBacteria; ABK37538; ABK37538; AHA_0468.
DR   GeneID; 4488886; -.
DR   KEGG; aha:AHA_0468; -.
DR   PATRIC; fig|380703.7.peg.460; -.
DR   eggNOG; ENOG41076E6; Bacteria.
DR   eggNOG; COG1587; LUCA.
DR   HOGENOM; HOG000247992; -.
DR   KO; K01719; -.
DR   OMA; TRPAEDC; -.
DR   BioCyc; AHYD380703:G1G7B-469-MONOMER; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0033014; P:tetrapyrrole biosynthetic process; IEA:InterPro.
DR   CDD; cd06578; HemD; 1.
DR   InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR   InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR   InterPro; IPR039793; UROS/Hem4.
DR   PANTHER; PTHR38042; PTHR38042; 1.
DR   Pfam; PF02602; HEM4; 1.
DR   SUPFAM; SSF69618; SSF69618; 1.
PE   4: Predicted;
DR   PRODOM; A0KFH5.
DR   SWISS-2DPAGE; A0KFH5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000756};
KW   Lyase {ECO:0000313|EMBL:ABK37538.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756}.
FT   DOMAIN       14    235       HEM4. {ECO:0000259|Pfam:PF02602}.
SQ   SEQUENCE   244 AA;  26217 MW;  2F1496759B8699F3 CRC64;
     MIPLVVRPAA QAAELAALLR QHGHAPLCCP LLETVAGSEL HRLPELLPQA DIVIAVSVHA
     VNFTHHFLLQ TGQTWPNIDY FAVGQASADA FSEVGIQALS PDDPRSEGLL ALPSLQQVNG
     KQVLILRGNG GRDLIARTLA SRGALVHYCA AYERHYPALD GDALTCHWQA AGLDSLLVTS
     GELLQRLLEL VPDQQLPWLH DRLLVVPSPR VAEMAAAAGF THITIAQGAS NQALTAALEL
     RKME
//

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