(data stored in SCRATCH zone)

SWISSPROT: A0KFR3_AERHH

ID   A0KFR3_AERHH            Unreviewed;       207 AA.
AC   A0KFR3;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 66.
DE   RecName: Full=Acyl-homoserine-lactone synthase {ECO:0000256|RuleBase:RU361135};
DE            EC=2.3.1.184 {ECO:0000256|RuleBase:RU361135};
DE   AltName: Full=Autoinducer synthesis protein {ECO:0000256|RuleBase:RU361135};
GN   OrderedLocusNames=AHA_0556 {ECO:0000313|EMBL:ABK38974.1};
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 /
OS   JCM 1027 / KCTC 2358 / NCIMB 9240).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703 {ECO:0000313|EMBL:ABK38974.1, ECO:0000313|Proteomes:UP000000756};
RN   [1] {ECO:0000313|EMBL:ABK38974.1, ECO:0000313|Proteomes:UP000000756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240
RC   {ECO:0000313|Proteomes:UP000000756};
RX   PubMed=16980456; DOI=10.1128/JB.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J.,
RA   Haft D., Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M.,
RA   Jin S., Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all
RT   trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-
CC         L-homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-
CC         thioadenosine; Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685,
CC         Rhea:RHEA-COMP:14125, ChEBI:CHEBI:15378, ChEBI:CHEBI:17509,
CC         ChEBI:CHEBI:55474, ChEBI:CHEBI:59789, ChEBI:CHEBI:64479,
CC         ChEBI:CHEBI:138651; EC=2.3.1.184;
CC         Evidence={ECO:0000256|RuleBase:RU361135};
CC   -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC       {ECO:0000256|PROSITE-ProRule:PRU00533,
CC       ECO:0000256|RuleBase:RU361135}.
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DR   EMBL; CP000462; ABK38974.1; -; Genomic_DNA.
DR   RefSeq; WP_011704528.1; NC_008570.1.
DR   RefSeq; YP_855089.1; NC_008570.1.
DR   SMR; A0KFR3; -.
DR   STRING; 380703.AHA_0556; -.
DR   EnsemblBacteria; ABK38974; ABK38974; AHA_0556.
DR   GeneID; 4488532; -.
DR   KEGG; aha:AHA_0556; -.
DR   PATRIC; fig|380703.7.peg.550; -.
DR   eggNOG; ENOG4105NNS; Bacteria.
DR   eggNOG; COG3916; LUCA.
DR   HOGENOM; HOG000271428; -.
DR   OMA; YMLKDTF; -.
DR   BioCyc; AHYD380703:G1G7B-557-MONOMER; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-UniRule.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR018311; Autoind_synth_CS.
DR   InterPro; IPR001690; Autoind_synthase.
DR   PANTHER; PTHR39322; PTHR39322; 1.
DR   Pfam; PF00765; Autoind_synth; 1.
DR   PRINTS; PR01549; AUTOINDCRSYN.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS00949; AUTOINDUCER_SYNTH_1; 1.
DR   PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0KFR3.
DR   SWISS-2DPAGE; A0KFR3.
KW   Autoinducer synthesis {ECO:0000256|PROSITE-ProRule:PRU00533,
KW   ECO:0000256|RuleBase:RU361135};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000756};
KW   Quorum sensing {ECO:0000256|PROSITE-ProRule:PRU00533,
KW   ECO:0000256|RuleBase:RU361135};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000756};
KW   S-adenosyl-L-methionine {ECO:0000256|RuleBase:RU361135};
KW   Transferase {ECO:0000256|RuleBase:RU361135}.
SQ   SEQUENCE   207 AA;  23613 MW;  727C0DA67008A5E7 CRC64;
     MLVFKGKLKE HPRWEVENEL YRFRNRVFSD RLGWDVESHR GLEQDSFDTP DTHWVLIEDE
     EGLCGCIRLL SCAQDYMLPS IFPTALAGEA PPRSNDVWEL TRLAIDAERA PRLGNGISEL
     TCIIFREVYA FAKAQGIREL VAVVSLPVER IFRRLGLPIE RLGHRQAVDL GAVRGVGIRF
     HLDERFARAV GQPLQGAYDE ARELVTE
//

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