(data stored in SCRATCH zone)

SWISSPROT: A0LEH0_SYNFM

ID   A0LEH0_SYNFM            Unreviewed;       571 AA.
AC   A0LEH0;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 90.
DE   SubName: Full=PAS/PAC sensor signal transduction histidine kinase {ECO:0000313|EMBL:ABK15822.1};
DE            EC=2.7.3.- {ECO:0000313|EMBL:ABK15822.1};
GN   OrderedLocusNames=Sfum_0119 {ECO:0000313|EMBL:ABK15822.1};
OS   Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543 {ECO:0000313|EMBL:ABK15822.1, ECO:0000313|Proteomes:UP000001784};
RN   [1] {ECO:0000313|EMBL:ABK15822.1, ECO:0000313|Proteomes:UP000001784}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10017 / MPOB {ECO:0000313|Proteomes:UP000001784};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA   McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J.,
RA   Sieber J., Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT   "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3;
CC         Evidence={ECO:0000256|SAAS:SAAS01118672};
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DR   EMBL; CP000478; ABK15822.1; -; Genomic_DNA.
DR   RefSeq; WP_011696995.1; NC_008554.1.
DR   STRING; 335543.Sfum_0119; -.
DR   EnsemblBacteria; ABK15822; ABK15822; Sfum_0119.
DR   KEGG; sfu:Sfum_0119; -.
DR   eggNOG; ENOG4105CUX; Bacteria.
DR   eggNOG; COG3852; LUCA.
DR   HOGENOM; HOG000010117; -.
DR   KO; K02668; -.
DR   OMA; ICRELCQ; -.
DR   OrthoDB; 1755994at2; -.
DR   BioCyc; SFUM335543:G1G7I-125-MONOMER; -.
DR   Proteomes; UP000001784; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd00075; HATPase_c; 1.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   TIGRFAMs; TIGR00229; sensory_box; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
DR   PRODOM; A0LEH0.
DR   SWISS-2DPAGE; A0LEH0.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00925949};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001784};
KW   Kinase {ECO:0000256|SAAS:SAAS01003914, ECO:0000313|EMBL:ABK15822.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00925310};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001784};
KW   Transferase {ECO:0000256|SAAS:SAAS01003669,
KW   ECO:0000313|EMBL:ABK15822.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     26     45       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     57     77       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     86    104       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    110    128       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    173    195       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      215    271       PAS. {ECO:0000259|PROSITE:PS50112}.
FT   DOMAIN      290    342       PAC. {ECO:0000259|PROSITE:PS50113}.
FT   DOMAIN      355    571       Histidine kinase. {ECO:0000259|PROSITE:
FT                                PS50109}.
SQ   SEQUENCE   571 AA;  63695 MW;  644C5140CC83CF39 CRC64;
     MQVDYDLEVN TINGELALRR KIQGLLLFRL LLAVFFLLLT IIVQSRRDQD LLSAHLQPIY
     FFSCILFVFT IVGALSLGRI RNLKRFAYVQ LFFDVGAVTV LIYLSGGVES LFSFLYMPVI
     ICAAVLLYRR GSLLTAAFSS VCYGTLLDLQ YFGWLLPLHV VNQTAQARDS GSYFHSILMN
     IAVFYLVAFM SGYLAEELQK SSLKIVEQSK DLRRLEVLHR NIVHSITSGL ITIGPSGEIL
     FCNNFAQDIL GLRSEPVTGR RFSSIFPGLD PLTWPRVVGP GPGHKKGPPE RPEIVYRNPL
     GEELHLGYAV SVLQNETGKW AGWIFIFQDL TQFKAMEEHL KRLERLVFAG RIAAEISHEI
     KNPLAAMSGA VQMLEDESIP DGSRARLMSI IHREIDRMNS LVKDFLWLAK STHGPENVEN
     VPVCDLIQEI LDLLSARNRV ASEHVIKTAF AASPISRIDP HHFRQIVWNL LVNALDAMPG
     GGHLTIAVGL HPSGDGSGRE TRIDISDSGS GIPRDARTRI FEPFFTTKSQ GTGLGLSIVY
     HLVEKANGRI EVTHHEEPCG TTFSLFFPLA S
//

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