(data stored in SCRATCH zone)

SWISSPROT: A0LFH6_SYNFM

ID   A0LFH6_SYNFM            Unreviewed;       773 AA.
AC   A0LFH6;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 86.
DE   SubName: Full=Cysteine synthases {ECO:0000313|EMBL:ABK16178.1};
GN   OrderedLocusNames=Sfum_0478 {ECO:0000313|EMBL:ABK16178.1};
OS   Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543 {ECO:0000313|EMBL:ABK16178.1, ECO:0000313|Proteomes:UP000001784};
RN   [1] {ECO:0000313|EMBL:ABK16178.1, ECO:0000313|Proteomes:UP000001784}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10017 / MPOB {ECO:0000313|Proteomes:UP000001784};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA   McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J.,
RA   Sieber J., Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT   "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|PIRSR:PIRSR605856-50};
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DR   EMBL; CP000478; ABK16178.1; -; Genomic_DNA.
DR   RefSeq; WP_011697351.1; NC_008554.1.
DR   STRING; 335543.Sfum_0478; -.
DR   EnsemblBacteria; ABK16178; ABK16178; Sfum_0478.
DR   KEGG; sfu:Sfum_0478; -.
DR   eggNOG; ENOG4108EX6; Bacteria.
DR   eggNOG; COG0031; LUCA.
DR   eggNOG; COG0215; LUCA.
DR   HOGENOM; HOG000011088; -.
DR   KO; K01883; -.
DR   OMA; TEWGNVR; -.
DR   OrthoDB; 952207at2; -.
DR   BioCyc; SFUM335543:G1G7I-488-MONOMER; -.
DR   Proteomes; UP000001784; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004124; F:cysteine synthase activity; IEA:InterPro.
DR   GO; GO:0004817; F:cysteine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   GO; GO:0006423; P:cysteinyl-tRNA aminoacylation; IEA:InterPro.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR015273; Cys-tRNA-synt_Ia_DALR.
DR   InterPro; IPR005856; Cys_synth.
DR   InterPro; IPR005858; CysM.
DR   InterPro; IPR001216; P-phosphate_BS.
DR   InterPro; IPR001926; PLP-dep.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR032678; tRNA-synt_1_cat_dom.
DR   InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR   InterPro; IPR036052; Trypto_synt_PLP_dependent.
DR   PANTHER; PTHR10314:SF100; PTHR10314:SF100; 1.
DR   Pfam; PF09190; DALR_2; 1.
DR   Pfam; PF00291; PALP; 1.
DR   Pfam; PF01406; tRNA-synt_1e; 1.
DR   SMART; SM00840; DALR_2; 1.
DR   SUPFAM; SSF47323; SSF47323; 1.
DR   SUPFAM; SSF53686; SSF53686; 1.
DR   TIGRFAMs; TIGR01136; cysKM; 1.
DR   PROSITE; PS00901; CYS_SYNTHASE; 1.
PE   4: Predicted;
DR   PRODOM; A0LFH6.
DR   SWISS-2DPAGE; A0LFH6.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001784};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR605856-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001784}.
FT   DOMAIN      659    729       DALR_2. {ECO:0000259|SMART:SM00840}.
FT   REGION      180    184       Pyridoxal phosphate binding.
FT                                {ECO:0000256|PIRSR:PIRSR605856-50}.
FT   BINDING      75     75       Pyridoxal phosphate. {ECO:0000256|PIRSR:
FT                                PIRSR605856-50}.
FT   BINDING     261    261       Pyridoxal phosphate. {ECO:0000256|PIRSR:
FT                                PIRSR605856-50}.
FT   MOD_RES      45     45       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|PIRSR:PIRSR605856-51}.
SQ   SEQUENCE   773 AA;  87137 MW;  113C94F38325BD93 CRC64;
     MKTVFSNVLE SIGNTPLIRI NRLNPNPAVT LYAKLEAKNP GGSIKDRTAL FMIESAERDG
     LLTHEKIIIE ATSGNTGIGL AIVAAVKGYR LMLAMPETAS LERQKILKAL GAEILLTPGN
     LGTDGAIEKV YSLVRENPDR YYMPDQFNNP ANPAAHHFGT GPEIFEQTEG KVNTVVVTLG
     TTGTAMGILQ AMKERDPAIR VVGVEPYPGH RVQGLKNMKE SYVPGIFDRH ALDQIIHIKD
     EDAFEMARRL AREEGIFTGM SSGAAMAIAV RVAEEMREGI VVAVLPDGGD RYLSTNLFTT
     LLEPDFHFFN FLERKKVDFK PVVEGKVRIC VTGPPLDNPL TLGESRRFLL ADFLARFLTA
     KSFSVEQVVQ VPDLDSRTIG GSLASRMPLS AYTRQQLDLI LEDLDRLAVK RAYRYPRSSE
     HINAITEDTK TLVNKGLAYD KLRSVYFNLS GSKDYGALSR VNLKKIRIGT TVDLDAYEKL
     NPRDFALLKR ATLAELKRGV CLKTDWGNVI PTWHIAAASV ALRELGAPID IQVSSVDFLF
     PHLENVREIG HALTGKPFAN VWMLSERMWS GADVKREDGL SEETPIRELN KLGYSPIEVR
     YWLLSNHYRK PIHVTPENID NARRGYHRLR EFIHRVQHAR TASQDHKLLP EMIYALEQGF
     FDALADDLNV PRAFACLFRF IRQFNPILDR EEFSEAQRRQ ITDVFYKING IMGIFDLELQ
     PLSEDDQELI HRREKARGSG EWDTADRIRE TLLQRGLKVI DTPLGTRWER VEH
//

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