(data stored in SCRATCH zone)

SWISSPROT: A0LFL7_SYNFM

ID   A0LFL7_SYNFM            Unreviewed;       374 AA.
AC   A0LFL7;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   08-MAY-2019, entry version 74.
DE   SubName: Full=Iron-containing alcohol dehydrogenase {ECO:0000313|EMBL:ABK16219.1};
GN   OrderedLocusNames=Sfum_0519 {ECO:0000313|EMBL:ABK16219.1};
OS   Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543 {ECO:0000313|EMBL:ABK16219.1, ECO:0000313|Proteomes:UP000001784};
RN   [1] {ECO:0000313|EMBL:ABK16219.1, ECO:0000313|Proteomes:UP000001784}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10017 / MPOB {ECO:0000313|Proteomes:UP000001784};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA   McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J.,
RA   Sieber J., Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT   "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000112-1};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR000112-
CC       1};
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DR   EMBL; CP000478; ABK16219.1; -; Genomic_DNA.
DR   RefSeq; WP_011697392.1; NC_008554.1.
DR   STRING; 335543.Sfum_0519; -.
DR   EnsemblBacteria; ABK16219; ABK16219; Sfum_0519.
DR   KEGG; sfu:Sfum_0519; -.
DR   eggNOG; ENOG4105DCT; Bacteria.
DR   eggNOG; COG0371; LUCA.
DR   HOGENOM; HOG000031784; -.
DR   KO; K00005; -.
DR   OMA; ETMHNEP; -.
DR   OrthoDB; 717704at2; -.
DR   BioCyc; SFUM335543:G1G7I-533-MONOMER; -.
DR   Proteomes; UP000001784; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   InterPro; IPR001670; ADH_Fe/GldA.
DR   InterPro; IPR018211; ADH_Fe_CS.
DR   InterPro; IPR016205; Glycerol_DH.
DR   PANTHER; PTHR43616; PTHR43616; 1.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   PIRSF; PIRSF000112; Glycerol_dehydrogenase; 1.
DR   PROSITE; PS00913; ADH_IRON_1; 1.
DR   PROSITE; PS00060; ADH_IRON_2; 1.
PE   4: Predicted;
DR   PRODOM; A0LFL7.
DR   SWISS-2DPAGE; A0LFL7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001784};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR000112-1};
KW   NAD {ECO:0000256|PIRSR:PIRSR000112-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001784};
KW   Zinc {ECO:0000256|PIRSR:PIRSR000112-1}.
FT   DOMAIN        8    349       Fe-ADH. {ECO:0000259|Pfam:PF00465}.
FT   NP_BIND      96    100       NAD. {ECO:0000256|PIRSR:PIRSR000112-3}.
FT   NP_BIND     118    121       NAD. {ECO:0000256|PIRSR:PIRSR000112-3}.
FT   METAL       173    173       Zinc; catalytic. {ECO:0000256|PIRSR:
FT                                PIRSR000112-1}.
FT   METAL       256    256       Zinc; catalytic. {ECO:0000256|PIRSR:
FT                                PIRSR000112-1}.
FT   METAL       273    273       Zinc; catalytic. {ECO:0000256|PIRSR:
FT                                PIRSR000112-1}.
FT   BINDING     123    123       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000112-2}.
FT   BINDING     127    127       NAD. {ECO:0000256|PIRSR:PIRSR000112-3}.
FT   BINDING     133    133       NAD. {ECO:0000256|PIRSR:PIRSR000112-3}.
FT   BINDING     173    173       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000112-2}.
FT   BINDING     256    256       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000112-2}.
FT   BINDING     273    273       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000112-2}.
SQ   SEQUENCE   374 AA;  38605 MW;  258735BB1DF0B509 CRC64;
     MFSVFSSPAR YTQGLDATAI LGAEMAGLGI EGPALIVAGG SALAQLSGTW RQTLGEVGCS
     YGIHRFGGEC SLAEILRIRH AAEALPARVV IGAGGGKALD AARASAAELG LPFVSCPTLA
     STDAPCSAVS VVYGESGAVE EVRILPRNPV LVLVDTRVIV QAPPRLLISG MGDALATWFE
     ARACAASGAR NLRGGRSTRS ALALAELCYR TLLEDGVEAV EAAGTQTVTP AFERIVEANT
     LLSGLGFESS GLAAAHSVHN GLTAAPQTRA FTHGEKVAFG TLVQLVLEKS DRSAIDEVMG
     FCAQVGLPVT LAQIGLRELS GEMLERIALR ATRTGESIHN EPFEVSANRV ADAILKADAL
     GRALPGNGKL PSPE
//

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