(data stored in ACNUC28527 zone)

SWISSPROT: A0RWH7_CENSY

ID   A0RWH7_CENSY            Unreviewed;       107 AA.
AC   A0RWH7;
DT   09-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2007, sequence version 1.
DT   11-DEC-2019, entry version 56.
DE   RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase {ECO:0000256|HAMAP-Rule:MF_00434};
DE            Short=PHS {ECO:0000256|HAMAP-Rule:MF_00434};
DE            EC=4.2.1.96 {ECO:0000256|HAMAP-Rule:MF_00434};
DE   AltName: Full=4-alpha-hydroxy-tetrahydropterin dehydratase {ECO:0000256|HAMAP-Rule:MF_00434};
DE   AltName: Full=Pterin carbinolamine dehydratase {ECO:0000256|HAMAP-Rule:MF_00434};
DE            Short=PCD {ECO:0000256|HAMAP-Rule:MF_00434};
GN   OrderedLocusNames=CENSYa_1064 {ECO:0000313|EMBL:ABK77694.1};
OS   Cenarchaeum symbiosum (strain A).
OC   Archaea; Thaumarchaeota; Cenarchaeales; Cenarchaeaceae; Cenarchaeum.
OX   NCBI_TaxID=414004 {ECO:0000313|EMBL:ABK77694.1, ECO:0000313|Proteomes:UP000000758};
RN   [1] {ECO:0000313|EMBL:ABK77694.1, ECO:0000313|Proteomes:UP000000758}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A {ECO:0000313|Proteomes:UP000000758};
RX   PubMed=17114289; DOI=10.1073/pnas.0608549103;
RA   Hallam S.J., Konstantinidis K.T., Putnam N., Schleper C., Watanabe Y.,
RA   Sugahara J., Preston C., de la Torre J., Richardson P.M., DeLong E.F.;
RT   "Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum
RT   symbiosum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:18296-18301(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin =
CC         (6R)-L-erythro-6,7-dihydrobiopterin + H2O; Xref=Rhea:RHEA:11920,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15642, ChEBI:CHEBI:43120; EC=4.2.1.96;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_00434};
CC   -!- SIMILARITY: Belongs to the pterin-4-alpha-carbinolamine dehydratase
CC       family. {ECO:0000256|HAMAP-Rule:MF_00434}.
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DR   EMBL; DP000238; ABK77694.1; -; Genomic_DNA.
DR   EnsemblBacteria; ABK77694; ABK77694; CENSYa_1064.
DR   KEGG; csy:CENSYa_1064; -.
DR   PATRIC; fig|414004.10.peg.978; -.
DR   HOGENOM; HOG000007680; -.
DR   KO; K01724; -.
DR   BioCyc; CSYM414004:G132A-1061-MONOMER; -.
DR   Proteomes; UP000000758; Chromosome.
DR   GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.30.1360.20; -; 1.
DR   HAMAP; MF_00434; Pterin_4_alpha; 1.
DR   InterPro; IPR036428; PCD_sf.
DR   InterPro; IPR001533; Pterin_deHydtase.
DR   PANTHER; PTHR12599; PTHR12599; 1.
DR   Pfam; PF01329; Pterin_4a; 1.
DR   SUPFAM; SSF55248; SSF55248; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0RWH7.
DR   SWISS-2DPAGE; A0RWH7.
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_00434, ECO:0000313|EMBL:ABK77694.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000758}.
SQ   SEQUENCE   107 AA;  12243 MW;  737F2CEE218787A4 CRC64;
     MSATYFNHAS TGDLMVTKLT DDELSSELAR LQDWEVRDGK LHKEFKFSSF NEAFGFMARA
     SMEIEKMNHH PEWCNVYNRL SVDLVTHDAG GITENDVRLA GMLDTLR
//

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