(data stored in ACNUC15260 zone)

SWISSPROT: A2AT86_MOUSE

ID   A2AT86_MOUSE            Unreviewed;       318 AA.
AC   A2AT86;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   08-MAY-2019, entry version 109.
DE   RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
GN   Name=Olfr1124 {ECO:0000313|Ensembl:ENSMUSP00000062513,
GN   ECO:0000313|MGI:MGI:3030958};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Muridae; Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000062513, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000062513, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000062513,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
RA   She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
RA   Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
RA   Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
RA   Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
RA   Lindblad-Toh K., Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of
RT   the mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000062513}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000062513};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSMUSP00000150244}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000150244};
RG   Ensembl;
RL   Submitted (DEC-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU363047, ECO:0000256|SAAS:SAAS00857205};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363047,
CC       ECO:0000256|SAAS:SAAS00857205}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000256|RuleBase:RU000688, ECO:0000256|SAAS:SAAS00857212}.
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DR   EMBL; AL928797; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_667239.2; NM_147028.2.
DR   STRING; 10090.ENSMUSP00000062513; -.
DR   Ensembl; ENSMUST00000062494; ENSMUSP00000062513; ENSMUSG00000050772.
DR   Ensembl; ENSMUST00000215909; ENSMUSP00000150244; ENSMUSG00000050772.
DR   GeneID; 259030; -.
DR   KEGG; mmu:259030; -.
DR   UCSC; uc008kny.1; mouse.
DR   CTD; 259030; -.
DR   MGI; MGI:3030958; Olfr1124.
DR   eggNOG; ENOG410IJMK; Eukaryota.
DR   eggNOG; ENOG410YADW; LUCA.
DR   GeneTree; ENSGT00950000182762; -.
DR   HOGENOM; HOG000041364; -.
DR   InParanoid; A2AT86; -.
DR   KO; K04257; -.
DR   OMA; VIGSWIS; -.
DR   OrthoDB; 961991at2759; -.
DR   PhylomeDB; A2AT86; -.
DR   TreeFam; TF337350; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   Bgee; ENSMUSG00000050772; Expressed in 2 organ(s), highest expression level in spleen.
DR   GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR   GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; A2AT86.
DR   SWISS-2DPAGE; A2AT86.
KW   Cell membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857207};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000589};
KW   G-protein coupled receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857203};
KW   Membrane {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857208};
KW   Olfaction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857209};
KW   Receptor {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857193};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Sensory transduction {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857210};
KW   Transducer {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857213};
KW   Transmembrane {ECO:0000256|RuleBase:RU000688,
KW   ECO:0000256|SAAS:SAAS00857211};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU363047,
KW   ECO:0000256|SAAS:SAAS00857194}.
FT   TRANSMEM     31     54       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM     66     88       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    100    126       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    203    222       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    243    267       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   TRANSMEM    279    298       Helical. {ECO:0000256|RuleBase:RU363047}.
FT   DOMAIN       47    296       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
SQ   SEQUENCE   318 AA;  35809 MW;  8D93666016329C07 CRC64;
     MNHQQKPQEG NLTNLKEFVL LGFSDVPDLQ WVLFGLLIAM YCFILLGNGT IVLITNVDSA
     LQTPMYFFLG NFSFLEICYV SITLPRMVFN LGTQRRTISF IACATQMCCI LILGATECFL
     LAVMAYDRYV AICNPLHYPL VMNQKVCSQL VIGSWISGIP IQIGQTSHIF SLSFCGSNQI
     NHFFCDIPPI LHLACGDIFI NEMMVFLGAF LFVLFPFLLI VFSYSKIIFT VLKLSSTKSR
     AKAFSTCSSH LAVVILFFGS GMITYFRSNS SHSGETDKVL SLFYTVVTPM FNPMVYSLRN
     KDVTIALRKF LCKQFVKI
//

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