(data stored in ACNUC11299 zone)

SWISSPROT: A2QAT7_ASPNC

ID   A2QAT7_ASPNC            Unreviewed;      1747 AA.
AC   A2QAT7;
DT   06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2007, sequence version 1.
DT   05-JUL-2017, entry version 58.
DE   RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE            EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN   ORFNames=An01g12710 {ECO:0000313|EMBL:CAK37321.1};
OS   Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=425011 {ECO:0000313|Proteomes:UP000006706};
RN   [1] {ECO:0000313|EMBL:CAK37321.1, ECO:0000313|Proteomes:UP000006706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 {ECO:0000313|Proteomes:UP000006706};
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G.,
RA   Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K.,
RA   Andersen M.R., Bendtsen J.D., Benen J.A., van den Berg M.,
RA   Breestraat S., Caddick M.X., Contreras R., Cornell M., Coutinho P.M.,
RA   Danchin E.G., Debets A.J., Dekker P., van Dijck P.W., van Dijk A.,
RA   Dijkhuizen L., Driessen A.J., d'Enfert C., Geysens S., Goosen C.,
RA   Groot G.S., de Groot P.W., Guillemette T., Henrissat B., Herweijer M.,
RA   van den Hombergh J.P., van den Hondel C.A., van der Heijden R.T.,
RA   van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P.,
RA   van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J., Meulenberg R.,
RA   Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M.,
RA   Pal K., van Peij N.N., Ram A.F., Rinas U., Roubos J.A., Sagt C.M.,
RA   Schmoll M., Sun J., Ussery D., Varga J., Vervecken W.,
RA   van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA   van Ooyen A.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory
RT   Aspergillus niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription
CC       of DNA into RNA using the four ribonucleoside triphosphates as
CC       substrates. {ECO:0000256|RuleBase:RU004279}.
CC   -!- CATALYTIC ACTIVITY: Nucleoside triphosphate + RNA(n) = diphosphate
CC       + RNA(n+1). {ECO:0000256|RuleBase:RU004279}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC       {ECO:0000256|RuleBase:RU004279}.
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DR   EMBL; AM269986; CAK37321.1; -; Genomic_DNA.
DR   RefSeq; XP_001389676.1; XM_001389639.2.
DR   STRING; 5061.CADANGAP00001227; -.
DR   EnsemblFungi; CAK37321; CAK37321; An01g12710.
DR   GeneID; 4977424; -.
DR   KEGG; ang:ANI_1_3202014; -.
DR   HOGENOM; HOG000222975; -.
DR   KO; K03006; -.
DR   OrthoDB; EOG092C01XQ; -.
DR   Proteomes; UP000006706; Chromosome 2R.
DR   GO; GO:0010494; C:cytoplasmic stress granule; IEA:EnsemblFungi.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005665; C:DNA-directed RNA polymerase II, core complex; IEA:EnsemblFungi.
DR   GO; GO:0000790; C:nuclear chromatin; IEA:EnsemblFungi.
DR   GO; GO:0003677; F:DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0001055; F:RNA polymerase II activity; IEA:EnsemblFungi.
DR   GO; GO:0003968; F:RNA-directed 5'-3' RNA polymerase activity; IEA:EnsemblFungi.
DR   GO; GO:0019985; P:translesion synthesis; IEA:EnsemblFungi.
DR   InterPro; IPR000722; RNA_pol_asu.
DR   InterPro; IPR000684; RNA_pol_II_repeat_euk.
DR   InterPro; IPR006592; RNA_pol_N.
DR   InterPro; IPR007080; RNA_pol_Rpb1_1.
DR   InterPro; IPR007066; RNA_pol_Rpb1_3.
DR   InterPro; IPR007083; RNA_pol_Rpb1_4.
DR   InterPro; IPR007081; RNA_pol_Rpb1_5.
DR   InterPro; IPR007075; RNA_pol_Rpb1_6.
DR   InterPro; IPR007073; RNA_pol_Rpb1_7.
DR   Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR   Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR   Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR   Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR   Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR   Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR   Pfam; PF04990; RNA_pol_Rpb1_7; 1.
DR   Pfam; PF05001; RNA_pol_Rpb1_R; 13.
DR   SMART; SM00663; RPOLA_N; 1.
DR   PROSITE; PS00115; RNA_POL_II_REPEAT; 3.
PE   3: Inferred from homology;
DR   PRODOM; A2QAT7.
DR   SWISS-2DPAGE; A2QAT7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006706};
KW   DNA-directed RNA polymerase {ECO:0000256|RuleBase:RU004279};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU004279,
KW   ECO:0000313|EMBL:CAK37321.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006706};
KW   Transcription {ECO:0000256|RuleBase:RU004279};
KW   Transferase {ECO:0000256|RuleBase:RU004279,
KW   ECO:0000313|EMBL:CAK37321.1}.
FT   DOMAIN      243    549       RPOLA_N. {ECO:0000259|SMART:SM00663}.
SQ   SEQUENCE   1747 AA;  193247 MW;  DC62B80D3C64048E CRC64;
     MANVYFPYSK APLRTIKEIQ FGLFSPEEIK RMSVVHVEYP ETMDDQRQRP RTKGLNDPRL
     GTIDRQWNCE TCEEGQKECP GHFGHIELAT PVYHIGFLTK IKKLLETVCH NCGKIKANTS
     DPKFLEALRM RDPKRRFDHI WRLSKDVLIC EADPPPDDDE PFSKENAKPV RMHGGCGNAQ
     PQIRKEGITL VGTWKPNKMM DEMDMQQPEK KVITPQVALN VFRNISYEDV RIMGLSNDYA
     RPEWMIITVL PVPPPPVRPS VLVGGSTSGQ RGEDDLTYKL AEIVRANQNV QRCEQEGAPE
     HVVREFESLL QYHVATYMDN DIAGQPKAMQ KSNRPVKAIR SRLKGKEGRL RQNLMGKRVD
     FSARTVITGD PNLSLEEVGV PKSIARTLTY PEVVTPYNIE KLQTLVSNGP NEHPGARYIV
     RDNGERIDLR HAKRAGGQQL LYGWKVERHI MDGDVILFNR QPSLHKESMM GHRVRVMPYS
     TFRLNLSVTT PYNADFDGDE MNLHVPQSEE SRAELSQLAL VPMNIVSPQR NGPLMGIVQD
     TLCGIYKICR RDVFLTKDQV MNIMMWVPDW DGVIPPPAIL KPRPRWTGKQ MISMALPSGL
     NLLRVDKDNS PLSEKFSPLA DGGLLIHNGQ LMYGMFSKKT VGASGGGVIH TIFNEYGHGT
     AVAFFNGAQR IVNYWLLHNG FSIGIGDTIP DELTIQRIEN CVRNRKKEVE SITASATDNT
     LEPLPGMNVR ETFESKVSRA LNNARDEAGS ETEKSLKDLN NAIQMARSGS KGSTINISQM
     TAVVGQQSVE GKRIPFGFKY RTLPHFTKDD YSPESRGFVE NSYLRGLTPT EFFFHAMAGR
     EGLIDTAVKT AETGYIQRKL VKALEEVMVK YDGTVRNSLG DIIQFIYGED GLDGAHIENQ
     RVDIIKCSDD KFRERFRVDL MDPERTLGPE VLEQANEIAG DVEVQRHLDE EWEELLKDRA
     FLRSVAKEDE EMMQLPINVQ RILETARTTF RIREGTISDL HPAEVIPQVR SLLDRLLVVR
     GNDIISREAQ ENATLLFKAQ LRSRLAFRRL VTEYSMNKLA FQHVIGAIES RFAKAGANPG
     EMVGVLAAQS IGEPATQMTL NTFHFAGVSS KNVTLGVPRL KEILNVATNI KTPSMTVYQE
     AARSFDKEGA KQLRSAVEHT SLRSVTEATE IYYDPDIQTT VIENDRDMVE SYFIIPEDVT
     DDASRQSKWL LRIILSRPKL LDKGLTVQDV ASRIKAAYPK DIAVIFSDNN ADEQVIRIRQ
     IQDYKEDEED DDIEYDVTLK KLEQHLLDTL TLRGVPGVER AFINEKSKVR VLEDGSLFAS
     KTDPLCKEWV LETSGSSLGE VLAIPGVDAT RTYSNQFIEV FEVFGIEAAR TAVLRELTQV
     LAFDGSYVNH RHLALLVDVM TVRGYLTPVT RHGINRADNG ALMRCSFEET VEILLEAAAF
     GELDDCRGVS ENLILGQMAP AGTGEFDIYL DQNLMNTVVS NNARFGVMGA IGAKDAIISD
     GAATQYDTGS PMQESAYIGT PDPESNFSPI RQAGAETPGG FTEYQPTGGF GGGFSPAATS
     PAGYSPSSPF SANPTSPGYS PTSSYSPTSP GMAITSPRFM STSPGFSPAS PSFAPTSPAY
     SPTSPAYGQA SPTSPSYSPT SPGFSPTSPN YSPTSPSFSP ASPAFSPTSP SYSPTSPAVG
     GVGRHLSPTS PTSPKYTPTS PGWSPTSPQT YSPTSPNFAG SPTSPGGPTS PGYSPTSPAF
     SPTSPRQ
//

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