(data stored in ACNUC5340 zone)

SWISSPROT: A2RAW7_ASPNC

ID   A2RAW7_ASPNC            Unreviewed;       766 AA.
AC   A2RAW7;
DT   06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2007, sequence version 1.
DT   11-DEC-2019, entry version 73.
DE   RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN   ORFNames=An18g04610 {ECO:0000313|EMBL:CAK43263.1};
OS   Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=425011 {ECO:0000313|Proteomes:UP000006706};
RN   [1] {ECO:0000313|EMBL:CAK43263.1, ECO:0000313|Proteomes:UP000006706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 {ECO:0000313|Proteomes:UP000006706};
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA   Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA   Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA   Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA   Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA   d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA   Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA   van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA   Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA   van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA   Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA   Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA   Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA   van Ooyen A.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT   niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
CC   -!- FUNCTION: Adaptins are components of the adaptor complexes which link
CC       clathrin to receptors in coated vesicles. Clathrin-associated protein
CC       complexes are believed to interact with the cytoplasmic tails of
CC       membrane proteins, leading to their selection and concentration.
CC       {ECO:0000256|PIRNR:PIRNR002291}.
CC   -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC       {ECO:0000256|PIRNR:PIRNR002291}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM270408; CAK43263.1; -; Genomic_DNA.
DR   PaxDb; A2RAW7; -.
DR   EnsemblFungi; CAK43263; CAK43263; An18g04610.
DR   HOGENOM; HOG000175744; -.
DR   Proteomes; UP000006706; Chromosome 8L.
DR   GO; GO:0030123; C:AP-3 adaptor complex; IEA:InterPro.
DR   GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR026740; AP3_beta.
DR   InterPro; IPR026739; AP_beta.
DR   InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   PANTHER; PTHR11134; PTHR11134; 1.
DR   PANTHER; PTHR11134:SF1; PTHR11134:SF1; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   PIRSF; PIRSF002291; AP_complex_beta; 2.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
DR   PRODOM; A2RAW7.
DR   SWISS-2DPAGE; A2RAW7.
KW   Membrane {ECO:0000256|PIRNR:PIRNR002291, ECO:0000256|SAAS:SAAS00468874};
KW   Protein transport {ECO:0000256|PIRNR:PIRNR002291,
KW   ECO:0000256|SAAS:SAAS00299732};
KW   Transport {ECO:0000256|PIRNR:PIRNR002291, ECO:0000256|SAAS:SAAS00468876}.
FT   DOMAIN          40..583
FT                   /note="Adaptin_N"
FT                   /evidence="ECO:0000259|Pfam:PF01602"
FT   REGION          645..766
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        645..659
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        667..686
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        712..756
FT                   /note="Acidic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   766 AA;  85377 MW;  F7BD6A6679A965DC CRC64;
     METISRISTM LETARELTLE AAQSAALSKG SSTGLSSRNL ATAHIKKLLD SRNDREVLDG
     MRRVITLMYR SEPSLPFFSA VVKNVASANL EVKKLVYIYL VHHAEAEPDL ALLSINAIQK
     SLTDQNPHSR AMALRTMSGI RVPVISQIVS LAIKRGCGDM SPHVRKAAAL AIPKCYRLDP
     STLPQLIGYL TTLLGDSQYF VLGPAVAAFL DVCPDRIDLI HKHYRSLVKK LVDMDEWSQL
     STLRLLTIYA RKCFPRKVQK GKQAVSEGFY EDDKTPESNG GDNEHEVLVL DPDLEFLLRT
     CKLLLQNRNS AVIVGVVRCF LYLGTPEYLE AAVGPLVALV RSPQDTQHVA LYNIVAVALK
     HPKPFTRYTT HFLVHAVDPP HIWRLKLEVL TLLFPHCGLH LKGVILSELE HFSQSADPDL
     VRESVRAIGR CAQSEPRSAD HCLRVLLSQI TSLDDNLVSE SLTVIRHLIQ QDPPAHEKTV
     IQLVKHLGLT KNPDARATIV WLVGEFAGVE PERNIAADIL RILVQDFANE SEAVKQQIIL
     LGAKVYLHHL MTLLWRYLLL LARYDTSYDL RDRARLYKAL LASPSSTQLA NLLLLAPKPV
     PHAPSPSETR KDLLIGSSTL VVGPDAGMLG LKGYQNLPEW VEFGQEPDPR LRENDIKPSV
     VEKSSMTAGE RLDRALKEHE STAATSSRQR DGRGVAVASS AKGKSLDQWL EEPETETEEE
     TETEEEVTDS EYEEVTDEET DEEEETDEEY ETDEEEQGQS AGLLKP
//

If you have problems or comments...

PBIL Back to PBIL home page