(data stored in ACNUC7421 zone)

SWISSPROT: A4AT69_MARSH

ID   A4AT69_MARSH            Unreviewed;      1269 AA.
AC   A4AT69;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   16-JAN-2019, entry version 79.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000256|HAMAP-Rule:MF_01321, ECO:0000256|RuleBase:RU363031};
DE            Short=RNAP subunit beta {ECO:0000256|HAMAP-Rule:MF_01321};
DE            EC=2.7.7.6 {ECO:0000256|HAMAP-Rule:MF_01321, ECO:0000256|RuleBase:RU363031};
DE   AltName: Full=RNA polymerase subunit beta {ECO:0000256|HAMAP-Rule:MF_01321};
DE   AltName: Full=Transcriptase subunit beta {ECO:0000256|HAMAP-Rule:MF_01321};
GN   Name=rpoB {ECO:0000256|HAMAP-Rule:MF_01321};
GN   OrderedLocusNames=FB2170_16181 {ECO:0000313|EMBL:EAR00639.1};
OS   Maribacter sp. (strain HTCC2170 / KCCM 42371).
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Maribacter.
OX   NCBI_TaxID=313603 {ECO:0000313|EMBL:EAR00639.1, ECO:0000313|Proteomes:UP000001602};
RN   [1] {ECO:0000313|EMBL:EAR00639.1, ECO:0000313|Proteomes:UP000001602}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC2170 / KCCM 42371 {ECO:0000313|Proteomes:UP000001602};
RX   PubMed=21037013; DOI=10.1128/JB.01207-10;
RA   Oh H.M., Kang I., Yang S.J., Jang Y., Vergin K.L., Giovannoni S.J.,
RA   Cho J.C.;
RT   "Complete genome sequence of strain HTCC2170, a novel member of the
RT   genus Maribacter in the family Flavobacteriaceae.";
RL   J. Bacteriol. 193:303-304(2011).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription
CC       of DNA into RNA using the four ribonucleoside triphosphates as
CC       substrates. {ECO:0000256|HAMAP-Rule:MF_01321,
CC       ECO:0000256|RuleBase:RU363031}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:11128, Rhea:RHEA-
CC         COMP:11129, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557,
CC         ChEBI:CHEBI:83400; EC=2.7.7.6; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01321, ECO:0000256|RuleBase:RU363031};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1
CC       beta' and 1 omega subunit. When a sigma factor is associated with
CC       the core the holoenzyme is formed, which can initiate
CC       transcription. {ECO:0000256|HAMAP-Rule:MF_01321,
CC       ECO:0000256|RuleBase:RU363031}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC       {ECO:0000256|HAMAP-Rule:MF_01321, ECO:0000256|RuleBase:RU000434}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002157; EAR00639.1; -; Genomic_DNA.
DR   RefSeq; WP_013304442.1; NC_014472.1.
DR   STRING; 313603.FB2170_16181; -.
DR   EnsemblBacteria; EAR00639; EAR00639; FB2170_16181.
DR   KEGG; fbc:FB2170_16181; -.
DR   eggNOG; ENOG4107QIH; Bacteria.
DR   eggNOG; COG0085; LUCA.
DR   HOGENOM; HOG000218612; -.
DR   KO; K03043; -.
DR   OMA; FMTWEGY; -.
DR   OrthoDB; 9601at2; -.
DR   BioCyc; MSP313603:G1GNS-10-MONOMER; -.
DR   Proteomes; UP000001602; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd00653; RNA_pol_B_RPB2; 1.
DR   Gene3D; 2.40.270.10; -; 3.
DR   Gene3D; 2.40.50.150; -; 1.
DR   HAMAP; MF_01321; RNApol_bact_RpoB; 1.
DR   InterPro; IPR019462; DNA-dir_RNA_pol_bsu_external_1.
DR   InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR   InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR   InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR   InterPro; IPR010243; RNA_pol_bsu_bac.
DR   InterPro; IPR007121; RNA_pol_bsu_CS.
DR   InterPro; IPR007644; RNA_pol_bsu_protrusion.
DR   InterPro; IPR007642; RNA_pol_Rpb2_2.
DR   InterPro; IPR007645; RNA_pol_Rpb2_3.
DR   InterPro; IPR007641; RNA_pol_Rpb2_7.
DR   InterPro; IPR014724; RNA_pol_RPB2_OB-fold.
DR   PANTHER; PTHR20856; PTHR20856; 1.
DR   Pfam; PF04563; RNA_pol_Rpb2_1; 1.
DR   Pfam; PF04561; RNA_pol_Rpb2_2; 2.
DR   Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR   Pfam; PF10385; RNA_pol_Rpb2_45; 1.
DR   Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR   Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR   TIGRFAMs; TIGR02013; rpoB; 1.
DR   PROSITE; PS01166; RNA_POL_BETA; 1.
PE   3: Inferred from homology;
DR   PRODOM; A4AT69.
DR   SWISS-2DPAGE; A4AT69.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001602};
KW   DNA-directed RNA polymerase {ECO:0000256|HAMAP-Rule:MF_01321,
KW   ECO:0000256|RuleBase:RU363031, ECO:0000313|EMBL:EAR00639.1};
KW   Nucleotidyltransferase {ECO:0000256|HAMAP-Rule:MF_01321,
KW   ECO:0000256|RuleBase:RU363031};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001602};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_01321,
KW   ECO:0000256|RuleBase:RU363031};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_01321,
KW   ECO:0000256|RuleBase:RU363031}.
FT   DOMAIN       24    459       RNA_pol_Rpb2_1. {ECO:0000259|Pfam:
FT                                PF04563}.
FT   DOMAIN      148    217       RNA_pol_Rpb2_2. {ECO:0000259|Pfam:
FT                                PF04561}.
FT   DOMAIN      294    414       RNA_pol_Rpb2_2. {ECO:0000259|Pfam:
FT                                PF04561}.
FT   DOMAIN      473    541       RNA_pol_Rpb2_3. {ECO:0000259|Pfam:
FT                                PF04565}.
FT   DOMAIN      551    617       RNA_pol_Rpb2_45. {ECO:0000259|Pfam:
FT                                PF10385}.
FT   DOMAIN      679   1192       RNA_pol_Rpb2_6. {ECO:0000259|Pfam:
FT                                PF00562}.
FT   DOMAIN     1194   1268       RNA_pol_Rpb2_7. {ECO:0000259|Pfam:
FT                                PF04560}.
SQ   SEQUENCE   1269 AA;  142601 MW;  7516DE51FCFD714B CRC64;
     MFTNQTERIN FASAKNTPEY PDFLDIQIKS FQDFFQLETK SDQRGTEGLY NTFMENFPIT
     DTRNQFVLEF LDYFIDPPRY SIQECIERGL TYSVPLKARL KLYCTDPEHE DFETIVQDVY
     LGTIPYMTPS GTFVINGAER VVVSQLHRSP GVFFGQSFHA NGTKLYSARV IPFKGSWIEF
     ATDINGVMYA YIDRKKKLPV TTLFRAIGFE SDKDILEIFD LSEEVKVSKA GLKKVLGRKL
     AARVLNTWHE DFVDEDTGEV VSIERNEIIL DRDTVLEKDH IEEILGTDVK TILLHKENNA
     QSDYAIIHNT LQKDPTNSEK EAVEHIYRQL RNAEPPDEET ARGIIDKLFF SDQRYNLGEV
     GRYRMNKKLQ LDIGMDKQVL TKEDIITIIK YLIELINSKA EIDDIDHLSN RRVRTVGEQL
     SSQFGVGLAR MARTIRERMN VRDNEVFTPI DLINAKTLSS VINSFFGTNQ LSQFMDQTNP
     LAEITHKRRL SALGPGGLSR ERAGFEVRDV HYTHYGRLCP IETPEGPNIG LISSLAVFAK
     VNPMGFLETP YRKVDGAKVD TKEYMYLSAE EEEGMKIAQA NIPLKDNGAI DSEKVIAREE
     GDFPVVDPKE VNYTDVAPNQ IASISASLIP FLEHDDANRA LMGSNMMRQA VPLLKPQSPI
     VGTGLERQVA SDSRVLINAE GDGTIEYVDS QKITIKYKRT DAERLISFDE DEKTYNLVKF
     RKTNQGTSIN LKPIVKKGDK VKKGQVLCEG YATEKGELAL GRNLTVAFMP WKGYNFEDAI
     VISEKVVRED IFTSIHVDEY ALEVRDTKLG AEELTHDIPN VSEEATKDLD ENGMIRIGAE
     VKPGDILIGK ITPKGESDPT PEEKLLRAIF GDKAGDVKDA SLKASPSLRG VVIDKKLFSR
     SIKDKRKRSE DKEAISTLEL EYEVKFQQLK DVLVEKLFTL INGKTSQGVL NDLGEEVLPK
     GKKYTMKMLN SVDDFAHLVA GTWTTDKDVN HSVADLLHNY KIKLNDLQGN LRRDKFTISV
     GDELPAGIMK LAKVYVAKKR KLKVGDKMAG RHGNKGIVSR IVRQEDMPFL EDGTPVDIVL
     NPLGVPSRMN IGQIYETVLG WAGLKLGRKY ATPIFDGATL DEINAYTDEA GIPRFGHTHL
     YDGGTGKRFD QAATVGVIYM LKLGHMVDDK MHARSIGPYS LITQQPLGGK AQFGGQRFGE
     MEVWALEAYG ASATLREILT VKSDDVIGRA KTYESIVKGE TMPEPGLPES FNVLMHELKG
     LGLDIRLEE
//

If you have problems or comments...

PBIL Back to PBIL home page