(data stored in SCRATCH zone)

SWISSPROT: A4F5Q0_SACEN

ID   A4F5Q0_SACEN            Unreviewed;      1314 AA.
AC   A4F5Q0;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   08-MAY-2019, entry version 81.
DE   SubName: Full=Polyketide-type polyunsaturated fatty acid synthase PfaA {ECO:0000313|EMBL:PFG93174.1};
DE   SubName: Full=Putative multi-domain beta-ketoacyl synthase {ECO:0000313|EMBL:CAL99374.1};
GN   OrderedLocusNames=SACE_0021 {ECO:0000313|EMBL:CAL99374.1};
GN   ORFNames=A8924_0404 {ECO:0000313|EMBL:PFG93174.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748
OS   / NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99374.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99374.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99374.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N.,
RA   Dickens S., Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93174.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93174.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AM420293; CAL99374.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93174.1; -; Genomic_DNA.
DR   RefSeq; WP_009945670.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0021; -.
DR   EnsemblBacteria; CAL99374; CAL99374; SACE_0021.
DR   KEGG; sen:SACE_0021; -.
DR   eggNOG; ENOG4107EEY; Bacteria.
DR   eggNOG; COG3321; LUCA.
DR   HOGENOM; HOG000294462; -.
DR   OMA; ESHWRID; -.
DR   OrthoDB; 1123553at2; -.
DR   BioCyc; SERY405948:SACE_RS00100-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0016740; F:transferase activity; IEA:InterPro.
DR   Gene3D; 1.10.1200.10; -; 1.
DR   Gene3D; 3.40.366.10; -; 1.
DR   Gene3D; 3.40.47.10; -; 1.
DR   InterPro; IPR001227; Ac_transferase_dom_sf.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR014043; Acyl_transferase.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR032821; KAsynt_C_assoc.
DR   InterPro; IPR018201; Ketoacyl_synth_AS.
DR   InterPro; IPR014031; Ketoacyl_synth_C.
DR   InterPro; IPR014030; Ketoacyl_synth_N.
DR   InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR   InterPro; IPR004432; Omega_3_polyunsat_FA_synth.
DR   InterPro; IPR020801; PKS_acyl_transferase.
DR   InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF00698; Acyl_transf_1; 1.
DR   Pfam; PF16197; KAsynt_C_assoc; 1.
DR   Pfam; PF00109; ketoacyl-synt; 1.
DR   Pfam; PF02801; Ketoacyl-synt_C; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00827; PKS_AT; 1.
DR   SMART; SM00825; PKS_KS; 1.
DR   SUPFAM; SSF47336; SSF47336; 1.
DR   SUPFAM; SSF52151; SSF52151; 1.
DR   SUPFAM; SSF53901; SSF53901; 1.
DR   SUPFAM; SSF55048; SSF55048; 1.
DR   TIGRFAMs; TIGR02813; omega_3_PfaA; 1.
DR   PROSITE; PS00606; B_KETOACYL_SYNTHASE; 1.
DR   PROSITE; PS50075; CARRIER; 1.
PE   4: Predicted;
DR   PRODOM; A4F5Q0.
DR   SWISS-2DPAGE; A4F5Q0.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006728,
KW   ECO:0000313|Proteomes:UP000225825};
KW   Phosphopantetheine {ECO:0000256|PROSITE-ProRule:PRU00258};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT   DOMAIN     1222   1302       Carrier. {ECO:0000259|PROSITE:PS50075}.
FT   MOD_RES    1260   1260       O-(pantetheine 4'-phosphoryl)serine.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00258}.
SQ   SEQUENCE   1314 AA;  138189 MW;  52BAA2B5949D6044 CRC64;
     MTPTAQRRLA DNPVAVVGLG ALFPRSGDLG EFWSNVVEAR DCIEEVPESH WRIDDHYDPD
     PEAPDKTYCK RGGFVPTVDF DPMEFGLPPN MLEVTDVLQL LSLVVAKQTL DDAGVRGAEW
     YDPSRTGAVL GVTGANSLTQ PLATRLQTPV LKEVVRSCGL TEQDADAIAD KFTRAFAPWE
     ENSFPGMLGN VVAGRLANRF DFGGKNCTVD AACASSLAAV DMAVDELVSG RADLMVTGGC
     DAENTILMYL CFSKTPAFSR SGRIRPFDES SDGTLIGEGM GMLALKRLED AERDGDRVYS
     VLRGMGSASD GRSKSIYAPR KEGQVLALRR AYQDAGFGPD QVGLVECHGT GTAVGDLTEL
     SALREVYAAE SDDTQFAAVG SVKSQIGHTK AAAGAASLIK VSLALHEKVL APTINVEQPR
     RDADFANSPF HVAARTRPWV HDPDRPVRRA AVSSFGFGGT NFHAVLEEHA ATSSTRRLHP
     GTRVHVWHAP TADELLDALR QDAEGIDPQE PVPAEDARLA VVATDEHELA SLREQSIERL
     SSEPGQESFD LPGGAHYRSR SLVGSERGGK VAALFAGQGS QYVGMGARAA VAVPPVRAAF
     DAASASTALG RVVFPPPAFD EETGKAQQEE LRRTEHAQPA IGALSSGQHR FLAELGFRAD
     GALGHSFGEL TALWAAGSLD DDGFHRLARA RGRAMAVSPD GGADPGTMAA VSAGPERVRE
     LLDGHDDVVV CNLNAPDQTV VGGGTEAVGE FVSAARDAGV DVRPLPVSGA FHTRYVAHAV
     EPFAAEVAGV AVREPAFPVY ADTAGASYGP DEEANRDVLV GQLTSTLSFA PRLEQLHDDG
     FRVFVEFGPR SLLSGMVRRT LADRGDVVVL SADAGPDRDG DRALKQLAAR LVVLGAPLTR
     LNRYAAEPAR REPGKGMTIP LNGVNHVSEA RREAYREALQ NGYRVDQQGG AAAQTGNGDA
     PPPPANGHAR QSNGHAPAQA SNGQVARQQS NGHAPAQASN GQVARQQSDG HAPAQQSDGH
     APAQQSDGQV ARQHNGQASG QQPADDRQPA AHDGVPAAFG PGSVAAEHMA AHREFLDGQL
     RVAQQLSSML QRESEQGPRD GMISGISAVA QQSVTVGESH MHASDVLRGF AEMETGAPPS
     PAVPPRRMPT AYSDQPAPPA QPAAPAPEPE EQIALPTPAP EPAPAPVPPQ APEPPQQAGD
     AVAPAEPART ASGEPESGGG PADAEEVRRT LLDIVAAKTG YPADMLDPGM DVEADLGIDS
     IKRVEIMGGL RERFPAMPEP SPEELAELRT LDDIVGLIAS AGASEGGQAQ APKA
//

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