(data stored in SCRATCH zone)

SWISSPROT: A4F5Z1_SACEN

ID   A4F5Z1_SACEN            Unreviewed;       235 AA.
AC   A4F5Z1;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   11-DEC-2019, entry version 75.
DE   SubName: Full=RNA polymerase sigma factor (Sigma-70 family) {ECO:0000313|EMBL:PFG93264.1};
DE   SubName: Full=RNA polymerase, sigma-70 factor, ECF subfamily {ECO:0000313|EMBL:CAL99465.1};
GN   OrderedLocusNames=SACE_0112 {ECO:0000313|EMBL:CAL99465.1};
GN   ORFNames=A8924_0498 {ECO:0000313|EMBL:PFG93264.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99465.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99465.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99465.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93264.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93264.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|SAAS:SAAS01160068}.
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DR   EMBL; AM420293; CAL99465.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93264.1; -; Genomic_DNA.
DR   RefSeq; WP_009949305.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0112; -.
DR   EnsemblBacteria; CAL99465; CAL99465; SACE_0112.
DR   KEGG; sen:SACE_0112; -.
DR   eggNOG; ENOG4107VIT; Bacteria.
DR   eggNOG; ENOG410ZF7D; LUCA.
DR   OMA; HRMRTHL; -.
DR   OrthoDB; 688188at2; -.
DR   BioCyc; SERY405948:SACE_RS00535-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR43133; PTHR43133; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF88659; SSF88659; 1.
DR   SUPFAM; SSF88946; SSF88946; 1.
DR   TIGRFAMs; TIGR02937; sigma70-ECF; 1.
PE   3: Inferred from homology;
DR   PRODOM; A4F5Z1.
DR   SWISS-2DPAGE; A4F5Z1.
KW   DNA-binding {ECO:0000256|SAAS:SAAS00611263};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW   Sigma factor {ECO:0000256|SAAS:SAAS00611278};
KW   Transcription {ECO:0000256|SAAS:SAAS00611290};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS00611294}.
FT   DOMAIN          39..96
FT                   /note="Sigma70_r2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          133..182
FT                   /note="Sigma70_r4_2"
FT                   /evidence="ECO:0000259|Pfam:PF08281"
FT   REGION          199..235
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   235 AA;  25954 MW;  D9D32899AF984C87 CRC64;
     MHEDAGGAAR PGPGRCEEID RALLDRLRAG DDLAYGEFYW RHVQAVRRFA MRAPRQGIDA
     DDVVAEVFLR VLRAVRAGAG PKDYVRTYLL TVVRRVQAEW CAARREEPML VDEIGKRIPG
     LRDHQGIQAE GELLARAFHR LPQRWREVLW RTEVEGHRPA SIAGQLGLSP NATAVLAHRA
     RRGLRAAYFQ AASAAEHRAG PENGADITGG PKSGATRAKA RRTFGAAPDL TCARQ
//

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