(data stored in SCRATCH zone)

SWISSPROT: A4F6M4_SACEN

ID   A4F6M4_SACEN            Unreviewed;       174 AA.
AC   A4F6M4;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   11-DEC-2019, entry version 60.
DE   SubName: Full=Cysteine dioxygenase type I {ECO:0000313|EMBL:CAL99698.1};
DE   SubName: Full=Putative metal-dependent enzyme (Double-stranded beta helix superfamily) {ECO:0000313|EMBL:PFG93501.1};
GN   OrderedLocusNames=SACE_0349 {ECO:0000313|EMBL:CAL99698.1};
GN   ORFNames=A8924_0744 {ECO:0000313|EMBL:PFG93501.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99698.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99698.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99698.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93501.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93501.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AM420293; CAL99698.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93501.1; -; Genomic_DNA.
DR   RefSeq; WP_009946502.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0349; -.
DR   EnsemblBacteria; CAL99698; CAL99698; SACE_0349.
DR   KEGG; sen:SACE_0349; -.
DR   eggNOG; ENOG4105TM1; Bacteria.
DR   eggNOG; COG5553; LUCA.
DR   HOGENOM; HOG000180757; -.
DR   OMA; DHRVWGL; -.
DR   OrthoDB; 1571420at2; -.
DR   BioCyc; SERY405948:SACE_RS01710-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR010300; CDO_1.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   PANTHER; PTHR12918; PTHR12918; 1.
DR   Pfam; PF05995; CDO_I; 1.
DR   SUPFAM; SSF51182; SSF51182; 1.
PE   4: Predicted;
DR   PRODOM; A4F6M4.
DR   SWISS-2DPAGE; A4F6M4.
KW   Dioxygenase {ECO:0000313|EMBL:CAL99698.1};
KW   Iron {ECO:0000256|PIRSR:PIRSR610300-51};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR610300-51};
KW   Oxidoreductase {ECO:0000313|EMBL:CAL99698.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW   Thioether bond {ECO:0000256|PIRSR:PIRSR610300-50}.
FT   METAL           84
FT                   /note="Iron; via tele nitrogen; catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR610300-51"
FT   METAL           86
FT                   /note="Iron; via tele nitrogen; catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR610300-51"
FT   METAL           135
FT                   /note="Iron; via tele nitrogen; catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR610300-51"
FT   CROSSLNK        90..151
FT                   /note="3'-(S-cysteinyl)-tyrosine (Cys-Tyr)"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR610300-50"
SQ   SEQUENCE   174 AA;  19088 MW;  340C4A55464A8BC0 CRC64;
     MTPQQIHLVQ AIRDVVRREE RAERTAELVA EALRPFLAVP DLLREDQRTG DPGSYTQHVL
     HVEPDGSFSV VALVWLPGQR TPVHDHVAWC VTGVYEGVEH EQRFTVHDGS SLVPTQQVTN
     PAGDVCGFAP PGDIHLVRNA CTTKAISLHV YGADIGTLGT SVRRTYDLPV RAAV
//

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