SWISSPROT: A4F6T8_SACEN

ID   A4F6T8_SACEN            Unreviewed;       853 AA.
AC   A4F6T8;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   08-MAY-2019, entry version 81.
DE   SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpC {ECO:0000313|EMBL:PFG93565.1};
DE   SubName: Full=Putative ATP-dependent Clp protease {ECO:0000313|EMBL:CAL99762.1};
GN   Name=clpC {ECO:0000313|EMBL:CAL99762.1};
GN   OrderedLocusNames=SACE_0414 {ECO:0000313|EMBL:CAL99762.1};
GN   ORFNames=A8924_0810 {ECO:0000313|EMBL:PFG93565.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748
OS   / NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99762.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99762.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99762.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N.,
RA   Dickens S., Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93565.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93565.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC       {ECO:0000256|SAAS:SAAS01144294}.
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DR   EMBL; AM420293; CAL99762.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93565.1; -; Genomic_DNA.
DR   RefSeq; WP_011873047.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0414; -.
DR   EnsemblBacteria; CAL99762; CAL99762; SACE_0414.
DR   KEGG; sen:SACE_0414; -.
DR   HOGENOM; HOG000218210; -.
DR   KO; K03696; -.
DR   OMA; TQVIRML; -.
DR   OrthoDB; 44062at2; -.
DR   BioCyc; SERY405948:SACE_RS02035-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1780.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR004176; Clp_N.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001943; UVR_dom.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF02861; Clp_N; 2.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   SUPFAM; SSF81923; SSF81923; 1.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS50151; UVR; 1.
PE   3: Inferred from homology;
DR   PRODOM; A4F6T8.
DR   SWISS-2DPAGE; A4F6T8.
KW   ATP-binding {ECO:0000256|SAAS:SAAS01144309,
KW   ECO:0000313|EMBL:PFG93565.1};
KW   Chaperone {ECO:0000256|SAAS:SAAS00127789};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006728,
KW   ECO:0000313|Proteomes:UP000225825};
KW   Hydrolase {ECO:0000313|EMBL:CAL99762.1};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS01144287};
KW   Protease {ECO:0000313|EMBL:CAL99762.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT   DOMAIN      421    456       UVR. {ECO:0000259|PROSITE:PS50151}.
FT   COILED      417    437       {ECO:0000256|SAM:Coils}.
FT   COILED      443    463       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   853 AA;  94717 MW;  9E4893BADC455E4B CRC64;
     MFERFTDRAR RVVVLAQEEA RMLNHNYIGT EHILLGLIHE GEGVAAKALE SLGIALEGVR
     QQVEEIIGQG QQAPSGHIPF TPRAKKVLEL SLREALQLGH NYIGTEHILL GLIREGEGVA
     AQVLVKLGAD LNRVRQQVLQ LLSGYQGKEP AEAGGRGEGT PSSSLVLDQF GRNLTQSARE
     SKLDPVIGRE KEIERIMQVL SRRTKNNPVL IGEAGVGKTA VVEGLAQKVV KGEVPETLKD
     KQLYTLDLGS LVAGSRYRGD FEERLKKVLK EIKTRGDIIL FIDEIHTLVG AGAAEGAIDA
     ASILKPMLAR GELQTIGATT LEEYRKYVEK DPALERRFQP IQVGEPSLEH TIEILKGLRD
     RYEAHHRVSI TDGALVSAAT LADRYINDRF LPDKAIDLID EAGARMRIRR MTAPPDLREF
     DEKIADVRRD KESAIDAQDF ERAARLRDEE KQLLGQKDER EKQWKAGDLD VVAEVDDEQI
     AEVLANWTGI PVFKLTEEET TRLLRMEDEL HKRIIGQDDA VKAVSQAIRR TRAGLKDPKR
     PSGSFIFAGP SGVGKTELSK ALAEFLFGDD DALVQIDMGE FHDRYTASRL FGAPPGYVGY
     EEGGQLTEKV RRKPFSVVLF DEIEKAHQEI YNTLLQVLED GRLTDGQGRT VDFKNTVLIF
     TSNLGTQDIS KAVGLGFSAG TDSESNYERM KSKVNEEMKK HFRPEFLNRI DDVIVFHQLT
     EAEIIQMVDL LGARVEKALK GKDMSLELTT LAKKLLAKRG FDPVLGARPL RRTIQREIED
     RLSEKILFGE IEPGQIVIVD VEGWDGEGSD DKAHFTFRGE TKPSLVPDAP PVDLAGSTGS
     STDDKSEGTS DQE
//