(data stored in ACNUC7421 zone)

SWISSPROT: A4F8I8_SACEN

ID   A4F8I8_SACEN            Unreviewed;       308 AA.
AC   A4F8I8;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   08-MAY-2019, entry version 72.
DE   SubName: Full=DNA-binding transcriptional LysR family regulator {ECO:0000313|EMBL:PFG94157.1};
DE   SubName: Full=LysR-family transcriptional regulator {ECO:0000313|EMBL:CAM00363.1};
GN   OrderedLocusNames=SACE_1031 {ECO:0000313|EMBL:CAM00363.1};
GN   ORFNames=A8924_1424 {ECO:0000313|EMBL:PFG94157.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748
OS   / NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM00363.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAM00363.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAM00363.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N.,
RA   Dickens S., Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG94157.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG94157.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|SAAS:SAAS01096700}.
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DR   EMBL; AM420293; CAM00363.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG94157.1; -; Genomic_DNA.
DR   RefSeq; WP_009949792.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_1031; -.
DR   EnsemblBacteria; CAM00363; CAM00363; SACE_1031.
DR   KEGG; sen:SACE_1031; -.
DR   eggNOG; ENOG4107W9C; Bacteria.
DR   eggNOG; ENOG410YPRW; LUCA.
DR   HOGENOM; HOG000233514; -.
DR   OMA; FLRTYMY; -.
DR   OrthoDB; 990666at2; -.
DR   BioCyc; SERY405948:SACE_RS05035-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
DR   PRODOM; A4F8I8.
DR   SWISS-2DPAGE; A4F8I8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006728,
KW   ECO:0000313|Proteomes:UP000225825};
KW   DNA-binding {ECO:0000256|SAAS:SAAS01096662,
KW   ECO:0000313|EMBL:PFG94157.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW   Transcription {ECO:0000256|SAAS:SAAS01096725};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS01096646}.
FT   DOMAIN       17     74       HTH lysR-type. {ECO:0000259|PROSITE:
FT                                PS50931}.
SQ   SEQUENCE   308 AA;  32811 MW;  70DC0E37FB543F6A CRC64;
     MTYETALSED ASQLAAHLSP TLALLRAVAS EGHLTRAAEQ LGIPQPTASR TLARLSDEIG
     APVIAPHGRG IRLTRTGRLL ASAATDALRS LEAGCREVVE EISPERGQVV LGFQHTMGGT
     LVPALIRGFR ADHPQVRFGL AQGARVDMLA GMLDGRIDFC LISPPPDPDP ALEWVPLRAE
     PLLAVLHTGH RLAGRAALAL SELADDDFVV TRHGYGLRQI FTELSDRAGF APRVAFESEE
     VDTARGLVAA GLGVALLPPA VPEAVPGTVE IPLDPAEHRT ICLTWPAHRA LPPAVRAFRD
     FASHRGLD
//

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