SWISSPROT: A5GQ41_SYNR3

ID   A5GQ41_SYNR3            Unreviewed;       460 AA.
AC   A5GQ41;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   08-MAY-2019, entry version 63.
DE   RecName: Full=Magnesium transporter MgtE {ECO:0000256|RuleBase:RU362011};
GN   Name=mgtE {ECO:0000313|EMBL:CAK27000.1};
GN   OrderedLocusNames=SynRCC307_0097 {ECO:0000313|EMBL:CAK27000.1};
OS   Synechococcus sp. (strain RCC307).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=316278 {ECO:0000313|EMBL:CAK27000.1, ECO:0000313|Proteomes:UP000001115};
RN   [1] {ECO:0000313|Proteomes:UP000001115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCC307 {ECO:0000313|Proteomes:UP000001115};
RG   Genoscope;
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a magnesium transporter.
CC       {ECO:0000256|RuleBase:RU362011}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|RuleBase:RU362011}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362011}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU362011}.
CC   -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC       {ECO:0000256|RuleBase:RU362011}.
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DR   EMBL; CT978603; CAK27000.1; -; Genomic_DNA.
DR   RefSeq; WP_011934515.1; NC_009482.1.
DR   STRING; 316278.SynRCC307_0097; -.
DR   EnsemblBacteria; CAK27000; CAK27000; SynRCC307_0097.
DR   KEGG; syr:SynRCC307_0097; -.
DR   eggNOG; ENOG4105CJW; Bacteria.
DR   eggNOG; COG2239; LUCA.
DR   HOGENOM; HOG000280152; -.
DR   KO; K06213; -.
DR   OMA; TGPFITT; -.
DR   OrthoDB; 1239195at2; -.
DR   BioCyc; SSP316278:G1GJL-98-MONOMER; -.
DR   Proteomes; UP000001115; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.357.20; -; 1.
DR   Gene3D; 1.25.60.10; -; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR006668; Mg_transptr_MgtE_intracell_dom.
DR   InterPro; IPR038076; MgtE_N_sf.
DR   InterPro; IPR038048; MgtE_transmem.
DR   InterPro; IPR006669; MgtE_transporter.
DR   InterPro; IPR006667; SLC41_membr_dom.
DR   InterPro; IPR036739; SLC41_membr_dom_sf.
DR   PANTHER; PTHR43773; PTHR43773; 1.
DR   Pfam; PF00571; CBS; 2.
DR   Pfam; PF01769; MgtE; 1.
DR   Pfam; PF03448; MgtE_N; 1.
DR   SMART; SM00116; CBS; 2.
DR   SMART; SM00924; MgtE_N; 1.
DR   SUPFAM; SSF161093; SSF161093; 1.
DR   TIGRFAMs; TIGR00400; mgtE; 1.
DR   PROSITE; PS51371; CBS; 2.
PE   3: Inferred from homology;
DR   PRODOM; A5GQ41.
DR   SWISS-2DPAGE; A5GQ41.
KW   CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW   Cell membrane {ECO:0000256|RuleBase:RU362011};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001115};
KW   Magnesium {ECO:0000256|RuleBase:RU362011};
KW   Membrane {ECO:0000256|RuleBase:RU362011};
KW   Metal-binding {ECO:0000256|RuleBase:RU362011};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001115};
KW   Transmembrane {ECO:0000256|RuleBase:RU362011};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362011};
KW   Transport {ECO:0000256|RuleBase:RU362011}.
FT   TRANSMEM    290    310       Helical. {ECO:0000256|RuleBase:RU362011}.
FT   TRANSMEM    316    343       Helical. {ECO:0000256|RuleBase:RU362011}.
FT   TRANSMEM    364    384       Helical. {ECO:0000256|RuleBase:RU362011}.
FT   TRANSMEM    390    418       Helical. {ECO:0000256|RuleBase:RU362011}.
FT   TRANSMEM    430    453       Helical. {ECO:0000256|RuleBase:RU362011}.
FT   DOMAIN      141    204       CBS. {ECO:0000259|PROSITE:PS51371}.
FT   DOMAIN      205    263       CBS. {ECO:0000259|PROSITE:PS51371}.
SQ   SEQUENCE   460 AA;  50044 MW;  66E3C82A4B24BFCE CRC64;
     MSDSATAIPE LTEYLQRLID AGNYDAVKQL LNPEQPVDAA EAISNLPTLQ QAIAFRLLPK
     DEAIEVYEYL EPAVQQSLLE RMRSSEVLEL VEEMSPDDRV RLFDELPAKV VRNLLQQLSP
     DERRVTAELL GYESETAGRL MTTEFIGLKE FTTAAQALEI VRRQASATET VYTLYVTDAA
     RRLTGILSLR QLVVSDPQAT VGEVMTRDVV RVQTGTDQEE VARLIQRYDF LALPVVDSED
     RLVGIVTVDD VIDVIEQEAT RDLYAAGAVQ AGDEDDYFKS NLFTVARRRV VWLVVLLLAN
     SGTAAVIASM DGVLKQVVVL AAFIPLLIGT GGNVGAQSST VIIRGLSTQR LQSLGSWRAI
     WREAVAGALL GFLLMLVVIP WAAYVSGGNW LVAWAAGISL VGITTLAATA GAALPLLFNR
     LGLDPALMSA PFIATATDVA GVFIYLRTAM ILLERFSSAS
//