(data stored in SCRATCH zone)

SWISSPROT: A5GRD5_SYNR3

ID   A5GRD5_SYNR3            Unreviewed;       282 AA.
AC   A5GRD5;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   08-MAY-2019, entry version 65.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase I {ECO:0000256|HAMAP-Rule:MF_01877};
DE            EC=2.1.1.198 {ECO:0000256|HAMAP-Rule:MF_01877};
DE   AltName: Full=16S rRNA 2'-O-ribose C1402 methyltransferase {ECO:0000256|HAMAP-Rule:MF_01877};
DE   AltName: Full=rRNA (cytidine-2'-O-)-methyltransferase RsmI {ECO:0000256|HAMAP-Rule:MF_01877};
GN   Name=rsmI {ECO:0000256|HAMAP-Rule:MF_01877};
GN   OrderedLocusNames=SynRCC307_0541 {ECO:0000313|EMBL:CAK27444.1};
OS   Synechococcus sp. (strain RCC307).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=316278 {ECO:0000313|EMBL:CAK27444.1, ECO:0000313|Proteomes:UP000001115};
RN   [1] {ECO:0000313|Proteomes:UP000001115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCC307 {ECO:0000313|Proteomes:UP000001115};
RG   Genoscope;
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the 2'-O-methylation of the ribose of cytidine
CC       1402 (C1402) in 16S rRNA. {ECO:0000256|HAMAP-Rule:MF_01877}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine =
CC         2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:42924, Rhea:RHEA-COMP:10285,
CC         Rhea:RHEA-COMP:10286, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:74495, ChEBI:CHEBI:82748;
CC         EC=2.1.1.198; Evidence={ECO:0000256|HAMAP-Rule:MF_01877};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01877}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmI
CC       family. {ECO:0000256|HAMAP-Rule:MF_01877}.
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DR   EMBL; CT978603; CAK27444.1; -; Genomic_DNA.
DR   RefSeq; WP_011934959.1; NC_009482.1.
DR   STRING; 316278.SynRCC307_0541; -.
DR   EnsemblBacteria; CAK27444; CAK27444; SynRCC307_0541.
DR   KEGG; syr:SynRCC307_0541; -.
DR   eggNOG; ENOG4105CU0; Bacteria.
DR   eggNOG; COG0313; LUCA.
DR   HOGENOM; HOG000195940; -.
DR   KO; K07056; -.
DR   OMA; RTMVFFE; -.
DR   OrthoDB; 1059309at2; -.
DR   BioCyc; SSP316278:G1GJL-528-MONOMER; -.
DR   Proteomes; UP000001115; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0070677; F:rRNA (cytosine-2'-O-)-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000453; P:enzyme-directed rRNA 2'-O-methylation; IEA:UniProtKB-UniRule.
DR   CDD; cd11648; RsmI; 1.
DR   Gene3D; 3.30.950.10; -; 1.
DR   Gene3D; 3.40.1010.10; -; 1.
DR   HAMAP; MF_01877; 16SrRNA_methyltr_I; 1.
DR   InterPro; IPR000878; 4pyrrol_Mease.
DR   InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR   InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR   InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR   InterPro; IPR008189; rRNA_ssu_MeTfrase_I.
DR   InterPro; IPR018063; SAM_MeTrfase_RsmI_CS.
DR   PANTHER; PTHR46111; PTHR46111; 1.
DR   Pfam; PF00590; TP_methylase; 1.
DR   PIRSF; PIRSF005917; MTase_YraL; 1.
DR   SUPFAM; SSF53790; SSF53790; 1.
DR   TIGRFAMs; TIGR00096; TIGR00096; 1.
DR   PROSITE; PS01296; RSMI; 1.
PE   3: Inferred from homology;
DR   PRODOM; A5GRD5.
DR   SWISS-2DPAGE; A5GRD5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001115};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01877};
KW   Methyltransferase {ECO:0000256|HAMAP-Rule:MF_01877,
KW   ECO:0000313|EMBL:CAK27444.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001115};
KW   rRNA processing {ECO:0000256|HAMAP-Rule:MF_01877};
KW   S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_01877};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_01877}.
FT   DOMAIN        9    206       TP_methylase. {ECO:0000259|Pfam:PF00590}.
SQ   SEQUENCE   282 AA;  30034 MW;  5318D77A3409AD50 CRC64;
     MKEPSPGVLY LVGTPIGHRG DLSPRAQQLL AAVDRVACED TRHSGLLLHG LGIQQKLISF
     HQHNQQQRIP ELLQALADGE AVALISDAGL PGISDPGEEL VAAARAAGRT VICIPGPCAA
     TTALVSSGLP SGRFCFEGFL PAKGRERQQR LTAIAQEERT SVLYEAPHRL LQLLKELIEH
     CGAERPVQVA RELTKRHEQH VGPTLAAALE HFSACKPQGE CTVVLGGAPA SEPEAWNADA
     LRAQLQQLQA GGLSASDAAR ELASRSGHSR RELYALLHSA AD
//

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