(data stored in SCRATCH zone)

SWISSPROT: A5GRS2_SYNR3

ID   A5GRS2_SYNR3            Unreviewed;       245 AA.
AC   A5GRS2;
DT   12-JUN-2007, integrated into UniProtKB/TrEMBL.
DT   12-JUN-2007, sequence version 1.
DT   08-MAY-2019, entry version 72.
DE   RecName: Full=N-acylglucosamine-6-phosphate 2-epimerase {ECO:0000256|SAAS:SAAS00761216};
DE            EC=5.1.3.9 {ECO:0000256|SAAS:SAAS00761216};
GN   Name=nanE {ECO:0000313|EMBL:CAK27581.1};
GN   OrderedLocusNames=SynRCC307_0678 {ECO:0000313|EMBL:CAK27581.1};
OS   Synechococcus sp. (strain RCC307).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=316278 {ECO:0000313|EMBL:CAK27581.1, ECO:0000313|Proteomes:UP000001115};
RN   [1] {ECO:0000313|EMBL:CAK27581.1, ECO:0000313|Proteomes:UP000001115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCC307 {ECO:0000313|Proteomes:UP000001115};
RA   Genoscope;
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to
CC       N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
CC       {ECO:0000256|SAAS:SAAS00761217}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an N-acyl-D-glucosamine 6-phosphate = an N-acyl-D-
CC         mannosamine 6-phosphate; Xref=Rhea:RHEA:23932,
CC         ChEBI:CHEBI:57599, ChEBI:CHEBI:57666; EC=5.1.3.9;
CC         Evidence={ECO:0000256|SAAS:SAAS01123353};
CC   -!- PATHWAY: Amino-sugar metabolism; N-acetylneuraminate degradation;
CC       D-fructose 6-phosphate from N-acetylneuraminate: step 3/5.
CC       {ECO:0000256|SAAS:SAAS00761210}.
CC   -!- SIMILARITY: Belongs to the NanE family.
CC       {ECO:0000256|SAAS:SAAS00761218}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CT978603; CAK27581.1; -; Genomic_DNA.
DR   STRING; 316278.SynRCC307_0678; -.
DR   EnsemblBacteria; CAK27581; CAK27581; SynRCC307_0678.
DR   KEGG; syr:SynRCC307_0678; -.
DR   eggNOG; ENOG4105C9S; Bacteria.
DR   eggNOG; COG3010; LUCA.
DR   HOGENOM; HOG000236669; -.
DR   KO; K01788; -.
DR   OMA; CEGGIAS; -.
DR   UniPathway; UPA00629; UER00682.
DR   Proteomes; UP000001115; Chromosome.
DR   GO; GO:0047465; F:N-acylglucosamine-6-phosphate 2-epimerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009385; F:N-acylmannosamine-6-phosphate 2-epimerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006051; P:N-acetylmannosamine metabolic process; IEA:InterPro.
DR   GO; GO:0019262; P:N-acetylneuraminate catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd04729; NanE; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR007260; NanE.
DR   InterPro; IPR011060; RibuloseP-bd_barrel.
DR   PANTHER; PTHR36204; PTHR36204; 1.
DR   Pfam; PF04131; NanE; 1.
DR   SUPFAM; SSF51366; SSF51366; 1.
PE   3: Inferred from homology;
DR   PRODOM; A5GRS2.
DR   SWISS-2DPAGE; A5GRS2.
KW   Carbohydrate metabolism {ECO:0000256|SAAS:SAAS00761211};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001115};
KW   Isomerase {ECO:0000256|SAAS:SAAS00761215,
KW   ECO:0000313|EMBL:CAK27581.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001115}.
SQ   SEQUENCE   245 AA;  25601 MW;  11762D550105A71C CRC64;
     MGWPPNRPPR LVNQGAALAL PKGLIVSVQA PAGSPMRDPD VIAAMAEASL RNGAVGVRLE
     SPEHIGAVRQ RCPKALIIGL WKRTFPGSSV YITPGWQEVS AVWSAGADVV AIDATERPRP
     DGEPLASLVE RVQRELGAPL MADVDSLANG LEAARLGCQW VGTTLFGYTE ATAAAQPPAW
     DLLGPLRQQL PAGVGLICEG GIASAEAAAQ ALRLGADAVV VGTAITGVDL QVQRYTRELQ
     KPVTN
//

If you have problems or comments...

PBIL Back to PBIL home page