(data stored in SCRATCH zone)

SWISSPROT: A8FPL0_SHESH

ID   A8FPL0_SHESH            Unreviewed;       163 AA.
AC   A8FPL0;
DT   13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2007, sequence version 1.
DT   07-JUN-2017, entry version 76.
DE   RecName: Full=Transcription elongation factor GreB {ECO:0000256|HAMAP-Rule:MF_00930};
DE   AltName: Full=Transcript cleavage factor GreB {ECO:0000256|HAMAP-Rule:MF_00930};
GN   Name=greB {ECO:0000256|HAMAP-Rule:MF_00930};
GN   OrderedLocusNames=Ssed_0170 {ECO:0000313|EMBL:ABV34783.1};
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104 {ECO:0000313|EMBL:ABV34783.1, ECO:0000313|Proteomes:UP000002015};
RN   [1] {ECO:0000313|EMBL:ABV34783.1, ECO:0000313|Proteomes:UP000002015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3 {ECO:0000313|EMBL:ABV34783.1,
RC   ECO:0000313|Proteomes:UP000002015};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Necessary for efficient RNA polymerase transcription
CC       elongation past template-encoded arresting sites. The arresting
CC       sites in DNA have the property of trapping a certain fraction of
CC       elongating RNA polymerases that pass through, resulting in locked
CC       ternary complexes. Cleavage of the nascent transcript by cleavage
CC       factors such as GreA or GreB allows the resumption of elongation
CC       from the new 3'terminus. GreB releases sequences of up to 9
CC       nucleotides in length. {ECO:0000256|HAMAP-Rule:MF_00930}.
CC   -!- SIMILARITY: Belongs to the GreA/GreB family. GreB subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_00930}.
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DR   EMBL; CP000821; ABV34783.1; -; Genomic_DNA.
DR   RefSeq; WP_012004309.1; NC_009831.1.
DR   ProteinModelPortal; A8FPL0; -.
DR   STRING; 425104.Ssed_0170; -.
DR   EnsemblBacteria; ABV34783; ABV34783; Ssed_0170.
DR   KEGG; sse:Ssed_0170; -.
DR   eggNOG; ENOG4108RRZ; Bacteria.
DR   eggNOG; COG0782; LUCA.
DR   HOGENOM; HOG000241145; -.
DR   KO; K04760; -.
DR   OMA; DQIFFGA; -.
DR   OrthoDB; POG091H00BT; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0070063; F:RNA polymerase binding; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.50.30; -; 1.
DR   HAMAP; MF_00105; GreA_GreB; 1.
DR   HAMAP; MF_00930; GreB; 1.
DR   InterPro; IPR018151; TF_GreA/GreB_CS.
DR   InterPro; IPR028624; Tscrpt_elong_fac_GreA/B.
DR   InterPro; IPR001437; Tscrpt_elong_fac_GreA/B_C.
DR   InterPro; IPR023459; Tscrpt_elong_fac_GreA/B_fam.
DR   InterPro; IPR022691; Tscrpt_elong_fac_GreA/B_N.
DR   InterPro; IPR006358; Tscrpt_elong_fac_GreB.
DR   Pfam; PF01272; GreA_GreB; 1.
DR   Pfam; PF03449; GreA_GreB_N; 1.
DR   PIRSF; PIRSF006092; GreA_GreB; 1.
DR   SUPFAM; SSF46557; SSF46557; 1.
DR   TIGRFAMs; TIGR01461; greB; 1.
DR   PROSITE; PS00829; GREAB_1; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FPL0.
DR   SWISS-2DPAGE; A8FPL0.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002015};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00930,
KW   ECO:0000256|SAAS:SAAS00003957};
KW   Elongation factor {ECO:0000313|EMBL:ABV34783.1};
KW   Protein biosynthesis {ECO:0000313|EMBL:ABV34783.1};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00930,
KW   ECO:0000256|SAAS:SAAS00018751};
KW   Transcription regulation {ECO:0000256|HAMAP-Rule:MF_00930,
KW   ECO:0000256|SAAS:SAAS00018712}.
FT   DOMAIN        5     74       GreA_GreB_N. {ECO:0000259|Pfam:PF03449}.
FT   DOMAIN       81    155       GreA_GreB. {ECO:0000259|Pfam:PF01272}.
SQ   SEQUENCE   163 AA;  19119 MW;  BD914386D890A68F CRC64;
     MKAMLITRKG WQALDKELKY LWKEYRPEIT KKVQEAAAQG DRSENADYTY NKRLLRQIDS
     RVRYLVKRVE ELQIVDYSPQ QEGKVFFGAW IELENEAGEI VQYRIVGKDE LDTKLGYITI
     DSPMARALIG KQVDDEVVVP TPLGPKEWYI NKIQYKSFED PQN
//

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