(data stored in SCRATCH zone)

SWISSPROT: A8FPN9_SHESH

ID   A8FPN9_SHESH            Unreviewed;       170 AA.
AC   A8FPN9;
DT   13-NOV-2007, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2007, sequence version 1.
DT   30-AUG-2017, entry version 55.
DE   RecName: Full=Cell division inhibitor SulA {ECO:0000256|SAAS:SAAS00384298};
GN   OrderedLocusNames=Ssed_0199 {ECO:0000313|EMBL:ABV34812.1};
OS   Shewanella sediminis (strain HAW-EB3).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=425104 {ECO:0000313|EMBL:ABV34812.1, ECO:0000313|Proteomes:UP000002015};
RN   [1] {ECO:0000313|EMBL:ABV34812.1, ECO:0000313|Proteomes:UP000002015}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAW-EB3 {ECO:0000313|EMBL:ABV34812.1,
RC   ECO:0000313|Proteomes:UP000002015};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Kim E., Zhao J.-S., Richardson P.;
RT   "Complete sequence of Shewanella sediminis HAW-EB3.";
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the SOS system and an inhibitor of cell
CC       division. Accumulation of SulA causes rapid cessation of cell
CC       division and the appearance of long, non-septate filaments. In the
CC       presence of GTP, binds a polymerization-competent form of FtsZ in
CC       a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore
CC       preventing it from participating in the assembly of the Z ring.
CC       This mechanism prevents the premature segregation of damaged DNA
CC       to daughter cells during cell division.
CC       {ECO:0000256|SAAS:SAAS00088373}.
CC   -!- SUBUNIT: Interacts with FtsZ. {ECO:0000256|SAAS:SAAS00571265}.
CC   -!- SIMILARITY: Belongs to the SulA family.
CC       {ECO:0000256|SAAS:SAAS00571263}.
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DR   EMBL; CP000821; ABV34812.1; -; Genomic_DNA.
DR   RefSeq; WP_012004338.1; NC_009831.1.
DR   ProteinModelPortal; A8FPN9; -.
DR   STRING; 425104.Ssed_0199; -.
DR   EnsemblBacteria; ABV34812; ABV34812; Ssed_0199.
DR   KEGG; sse:Ssed_0199; -.
DR   eggNOG; ENOG4106F7S; Bacteria.
DR   eggNOG; ENOG410Y6WU; LUCA.
DR   HOGENOM; HOG000001892; -.
DR   KO; K13053; -.
DR   OMA; GRWIVLI; -.
DR   OrthoDB; POG091H0S0W; -.
DR   BioCyc; SSED425104:GH7Q-202-MONOMER; -.
DR   Proteomes; UP000002015; Chromosome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0051782; P:negative regulation of cell division; IEA:InterPro.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR   InterPro; IPR004596; Cell_div_suppressor_SulA.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF03846; SulA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
DR   PRODOM; A8FPN9.
DR   SWISS-2DPAGE; A8FPN9.
KW   Cell cycle {ECO:0000256|SAAS:SAAS00088378};
KW   Cell division {ECO:0000256|SAAS:SAAS00461185};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002015};
KW   DNA damage {ECO:0000256|SAAS:SAAS00088387};
KW   Septation {ECO:0000256|SAAS:SAAS00088386};
KW   SOS response {ECO:0000256|SAAS:SAAS00088377}.
SQ   SEQUENCE   170 AA;  18539 MW;  5944EB3CDB040ACE CRC64;
     MNSLIGNSPR HPGLWVNLED PLSNELQGCT VSSVTTHTQG RDELQMLSAQ LASLSHRGQW
     IVLISPPNIG YKQMLTDAGV RMDRVLLVHA KDEVETLWAM EKALTSGTSS AVISWTQSLD
     ARDNRRLQIV AKSARAVGIV IEVANGHLHG KAHMNGVEAF NQPSLFGSLH
//

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