(data stored in SCRATCH zone)

SWISSPROT: A8LDT5_FRASN

ID   A8LDT5_FRASN            Unreviewed;       612 AA.
AC   A8LDT5;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   08-MAY-2019, entry version 76.
DE   RecName: Full=Chaperone protein DnaK {ECO:0000256|HAMAP-Rule:MF_00332};
DE   AltName: Full=HSP70 {ECO:0000256|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock 70 kDa protein {ECO:0000256|HAMAP-Rule:MF_00332};
DE   AltName: Full=Heat shock protein 70 {ECO:0000256|HAMAP-Rule:MF_00332};
GN   Name=dnaK {ECO:0000256|HAMAP-Rule:MF_00332};
GN   OrderedLocusNames=Franean1_0233 {ECO:0000313|EMBL:ABW09700.1};
OS   Frankia sp. (strain EAN1pec).
OC   Bacteria; Actinobacteria; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=298653 {ECO:0000313|EMBL:ABW09700.1, ECO:0000313|Proteomes:UP000001313};
RN   [1] {ECO:0000313|Proteomes:UP000001313}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EAN1pec {ECO:0000313|Proteomes:UP000001313};
RX   PubMed=17151343; DOI=10.1101/gr.5798407;
RA   Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA   Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N.,
RA   Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N.,
RA   Francino M.P., Goltsman E., Huang Y., Kopp O.R., Labarre L.,
RA   Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E.,
RA   Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z.,
RA   Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D.,
RA   Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R.;
RT   "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT   reflect host range and host plant biogeography.";
RL   Genome Res. 17:7-15(2007).
CC   -!- FUNCTION: Acts as a chaperone. {ECO:0000256|HAMAP-Rule:MF_00332}.
CC   -!- INDUCTION: By stress conditions e.g. heat shock.
CC       {ECO:0000256|HAMAP-Rule:MF_00332}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|HAMAP-Rule:MF_00332, ECO:0000256|RuleBase:RU003322}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000820; ABW09700.1; -; Genomic_DNA.
DR   RefSeq; WP_012157677.1; NC_009921.1.
DR   STRING; 298653.Franean1_0233; -.
DR   EnsemblBacteria; ABW09700; ABW09700; Franean1_0233.
DR   KEGG; fre:Franean1_0233; -.
DR   eggNOG; ENOG4105CFG; Bacteria.
DR   eggNOG; COG0443; LUCA.
DR   HOGENOM; HOG000228136; -.
DR   KO; K04043; -.
DR   OMA; ISIKRHM; -.
DR   OrthoDB; 161217at2; -.
DR   BioCyc; FSP298653:G1G9X-225-MONOMER; -.
DR   Proteomes; UP000001313; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   HAMAP; MF_00332; DnaK; 1.
DR   InterPro; IPR012725; Chaperone_DnaK.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 1.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   TIGRFAMs; TIGR02350; prok_dnaK; 1.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; A8LDT5.
DR   SWISS-2DPAGE; A8LDT5.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00332,
KW   ECO:0000256|RuleBase:RU003322};
KW   Chaperone {ECO:0000256|HAMAP-Rule:MF_00332};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001313};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00332,
KW   ECO:0000256|RuleBase:RU003322};
KW   Oxidoreductase {ECO:0000313|EMBL:ABW09700.1};
KW   Phosphoprotein {ECO:0000256|HAMAP-Rule:MF_00332};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001313};
KW   Stress response {ECO:0000256|HAMAP-Rule:MF_00332}.
FT   COILED      231    251       {ECO:0000256|SAM:Coils}.
FT   COILED      489    509       {ECO:0000256|SAM:Coils}.
FT   MOD_RES     175    175       Phosphothreonine; by autocatalysis.
FT                                {ECO:0000256|HAMAP-Rule:MF_00332}.
SQ   SEQUENCE   612 AA;  65328 MW;  449FFF7938A1BBD5 CRC64;
     MARAVGIDLG TTNSVVSVLE GGEPTVIANA EGSRTTPSVV AFAKNGEVLV GEVAKRQAVT
     NVERTIRSVK RHMGTDWKMT VDSKEFTPQE ISARILQKLK RDAEAYLGES VSDAVITVPA
     YFDDAQRQAT TEAGTIAGLN VLRIVNEPTA AALAYGLDKG EKEQTILVFD LGGGTFDVSL
     LEIGDGVVEV KSTSGDTQLG GDDWDQRITD HLIKTFNGQH GVDLGKDKMA LQRLREAAEK
     AKIELSQSTQ TSINLPYITA SAEGPLHLDV SLSRAELQRM TQDLIDRCKG PFQQAVKDAG
     IKISDVDHVV LVGGSTRMPA VVDLVRELTG GKEPNKGVNP DEVVAVGASL QAGVLKGEVK
     DVLLLDVTPL SLGIETKGGI MTKLIERNTT IPTKRSEIFT TAEDSQPSVQ IQVFQGEREM
     AAYNKKLGMF ELTGLPPAPR GMPQIEVTFD IDANGIVHVS AKDLGTGKEQ SMTITGGSAL
     PKDDINRMVQ DAEQYAEEDR QRREEAETRN RAESLVYSTE RFLAENGDKI EAGVKSDVEE
     KLSTLRGAVG GTDIAAIREA ADELTKASQA MGESMYAQAA GAQGAPGAPG AGAGQADDDV
     VDAEIVDEED KK
//

If you have problems or comments...

PBIL Back to PBIL home page