(data stored in ACNUC13479 zone)

SWISSPROT: DGK3_ARATH

ID   DGK3_ARATH              Reviewed;         488 AA.
AC   Q8VZG1; Q9ZV46;
DT   01-MAY-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   07-JUN-2017, entry version 96.
DE   RecName: Full=Diacylglycerol kinase 3;
DE            Short=AtDGK3;
DE            Short=DAG kinase 3;
DE            EC=2.7.1.107;
DE   AltName: Full=Diglyceride kinase 3;
DE            Short=DGK 3;
GN   Name=DGK3; OrderedLocusNames=At2g18730; ORFNames=MSF3.11;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L.,
RA   Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L.,
RA   Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H.,
RA   Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D.,
RA   Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M.,
RA   Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Portal (Araport);
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
RA   Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
RA   Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
RA   Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
RA   Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
RA   Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
RA   Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
RA   Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
RA   Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
RA   Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
RA   Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
RA   Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
CC   -!- FUNCTION: Phosphorylates the second messenger diacylglycerol (DAG)
CC       to generate phosphatidic acid (PA), another important signaling
CC       molecule. PA is required for plant development and responses to
CC       abiotic stress and pathogen attack. May be involved in the
CC       accumulation of PA during cold stress (By similarity).
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY: ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-
CC       diacyl-sn-glycerol 3-phosphate.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic diacylglycerol kinase
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD08942.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
DR   EMBL; AC005724; AAD08942.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC06799.1; -; Genomic_DNA.
DR   EMBL; AY064982; AAL57635.1; -; mRNA.
DR   EMBL; AY141990; AAM98254.1; -; mRNA.
DR   PIR; H84567; H84567.
DR   RefSeq; NP_849980.1; NM_179649.4.
DR   UniGene; At.27505; -.
DR   ProteinModelPortal; Q8VZG1; -.
DR   BioGrid; 1745; 7.
DR   IntAct; Q8VZG1; 7.
DR   STRING; 3702.AT2G18730.1; -.
DR   iPTMnet; Q8VZG1; -.
DR   SwissPalm; Q8VZG1; -.
DR   PaxDb; Q8VZG1; -.
DR   PRIDE; Q8VZG1; -.
DR   EnsemblPlants; AT2G18730.1; AT2G18730.1; AT2G18730.
DR   GeneID; 816388; -.
DR   Gramene; AT2G18730.1; AT2G18730.1; AT2G18730.
DR   KEGG; ath:AT2G18730; -.
DR   Araport; AT2G18730; -.
DR   TAIR; locus:2053978; AT2G18730.
DR   eggNOG; KOG1169; Eukaryota.
DR   eggNOG; ENOG410XQVB; LUCA.
DR   HOGENOM; HOG000239559; -.
DR   InParanoid; Q8VZG1; -.
DR   KO; K00901; -.
DR   OMA; PMSTEYS; -.
DR   OrthoDB; EOG09360AZ1; -.
DR   PhylomeDB; Q8VZG1; -.
DR   BioCyc; ARA:AT2G18730-MONOMER; -.
DR   PRO; PR:Q8VZG1; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q8VZG1; baseline and differential.
DR   Genevisible; Q8VZG1; AT.
DR   GO; GO:0016020; C:membrane; IDA:TAIR.
DR   GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR   GO; GO:0009506; C:plasmodesma; IDA:TAIR.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 3.40.50.10330; -; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_dom_1.
DR   InterPro; IPR000756; Diacylglycerol_kin_accessory.
DR   InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR   InterPro; IPR016961; Diacylglycerol_kinase_pln.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase.
DR   Pfam; PF00609; DAGK_acc; 1.
DR   Pfam; PF00781; DAGK_cat; 1.
DR   PIRSF; PIRSF030829; Diacylglycerol_kinase_pln; 1.
DR   SMART; SM00045; DAGKa; 1.
DR   SMART; SM00046; DAGKc; 1.
DR   SUPFAM; SSF111331; SSF111331; 2.
DR   PROSITE; PS50146; DAGK; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q8VZG1.
DR   SWISS-2DPAGE; Q8VZG1.
KW   ATP-binding; Complete proteome; Kinase; Nucleotide-binding;
KW   Plant defense; Reference proteome; Stress response; Transferase.
FT   CHAIN         1    488       Diacylglycerol kinase 3.
FT                                /FTId=PRO_0000422111.
FT   DOMAIN       87    245       DAGKc. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00783}.
SQ   SEQUENCE   488 AA;  53881 MW;  126012C84473CA3F CRC64;
     MDSPVSKTDA SKEKFVASRP STADSKTMRG CGLANLAWVG VDKVELRQRL MMPEYLRLAM
     RDCIKRKDSS AIPDHLLLPG GAVADMAPHA PMVVFINPNS GGRHGPVLKE RLQQLMSEEQ
     VFDLTEVKPH EFVRYGLGCL EKVAAEGDEC AKECRARLRI MVAGGDGTVG WVLGCLGELN
     KDGKSQIPPV GVIPLGTGND LSRSFGWGGS FPFAWRSAVK RTLHRASMGP VARLDSWKIL
     VSMPSGEVVD PPYSLKPAEE NELDQGLDAG IDAPPLAKAY EGVFYNYLSI GMDAQVAYGF
     HHLRNTKPYL AQGPISNKII YSSFGCSQGW FCTPCVNDPG LRGLRNIMKI HIKKVNCSQW
     EEIAVPKNVR SIVALNLHSY GSGSHPWGNL KPDYLEKRGF VEAHCDDGLI EIFGFKQGWH
     ASFVMAELIS AKHIAQAAAV RFELRGGDWR DAFLQMDGEP WKQPMSTEYS TFVEIKKVPY
     QSLMINNE
//

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