(data stored in ACNUC13479 zone)

SWISSPROT: CB60C_ARATH

ID   CB60C_ARATH             Reviewed;         622 AA.
AC   C0SV51; Q944Q2; Q9ZV44;
DT   27-MAY-2015, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   30-AUG-2017, entry version 66.
DE   RecName: Full=Calmodulin-binding protein 60 C {ECO:0000303|PubMed:11782485};
GN   Name=CBP60C {ECO:0000303|PubMed:11782485};
GN   OrderedLocusNames=At2g18750 {ECO:0000312|Araport:AT2G18750};
GN   ORFNames=MSF3.13 {ECO:0000312|EMBL:AAD08944.2};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|EMBL:BAH30392.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L.,
RA   Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L.,
RA   Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H.,
RA   Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D.,
RA   Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M.,
RA   Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RG   The Arabidopsis Information Portal (Araport);
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
RA   Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
RA   Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
RA   Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
RA   Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
RA   Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
RA   Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
RA   Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
RA   Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
RA   Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
RA   Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
RA   Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   STRAIN=cv. Columbia;
RA   Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N.,
RA   Takiguchi Y., Takagi M.;
RT   "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11782485; DOI=10.1074/jbc.M111626200;
RA   Reddy V.S., Ali G.S., Reddy A.S.N.;
RT   "Genes encoding calmodulin-binding proteins in the Arabidopsis
RT   genome.";
RL   J. Biol. Chem. 277:9840-9852(2002).
CC   -!- FUNCTION: Transcription activator that binds DNA in a sequence-
CC       specific manner, likely 5'-GAAATTTTGG-3', to promote the
CC       expression of target genes. {ECO:0000250|UniProtKB:F4K2R6}.
CC   -!- SUBUNIT: Interacts with calmodulin (CaM).
CC       {ECO:0000250|UniProtKB:F4K2R6}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9C9T2}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=C0SV51-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=C0SV51-2; Sequence=VSP_057663;
CC         Note=No experimental confirmation available. {ECO:0000305};
CC   -!- TISSUE SPECIFICITY: Expressed in stems, flowers and root.
CC       {ECO:0000269|PubMed:11782485}.
CC   -!- SIMILARITY: Belongs to the plant ACBP60 protein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD08944.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
DR   EMBL; AC005724; AAD08944.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC06802.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06803.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06804.1; -; Genomic_DNA.
DR   EMBL; AF424622; AAL11615.1; -; mRNA.
DR   EMBL; AY143850; AAN28789.1; -; mRNA.
DR   EMBL; AB493554; BAH30392.1; -; mRNA.
DR   PIR; B84568; B84568.
DR   RefSeq; NP_001031372.1; NM_001036295.2. [C0SV51-1]
DR   RefSeq; NP_001189550.1; NM_001202621.2. [C0SV51-1]
DR   RefSeq; NP_565441.2; NM_127431.3. [C0SV51-1]
DR   UniGene; At.20176; -.
DR   STRING; 3702.AT2G18750.1; -.
DR   iPTMnet; C0SV51; -.
DR   PaxDb; C0SV51; -.
DR   EnsemblPlants; AT2G18750.1; AT2G18750.1; AT2G18750. [C0SV51-1]
DR   EnsemblPlants; AT2G18750.2; AT2G18750.2; AT2G18750. [C0SV51-1]
DR   EnsemblPlants; AT2G18750.3; AT2G18750.3; AT2G18750. [C0SV51-1]
DR   GeneID; 816390; -.
DR   Gramene; AT2G18750.1; AT2G18750.1; AT2G18750.
DR   Gramene; AT2G18750.2; AT2G18750.2; AT2G18750.
DR   Gramene; AT2G18750.3; AT2G18750.3; AT2G18750.
DR   KEGG; ath:AT2G18750; -.
DR   Araport; AT2G18750; -.
DR   TAIR; locus:2054000; AT2G18750.
DR   eggNOG; ENOG410IJDW; Eukaryota.
DR   eggNOG; ENOG4111EYI; LUCA.
DR   HOGENOM; HOG000237471; -.
DR   InParanoid; C0SV51; -.
DR   OMA; SITMQYD; -.
DR   OrthoDB; EOG09360473; -.
DR   PhylomeDB; C0SV51; -.
DR   PRO; PR:C0SV51; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; C0SV51; baseline and differential.
DR   Genevisible; C0SV51; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   InterPro; IPR012416; CBP60.
DR   Pfam; PF07887; Calmodulin_bind; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; C0SV51.
DR   SWISS-2DPAGE; C0SV51.
KW   Activator; Alternative splicing; Calmodulin-binding;
KW   Complete proteome; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN         1    622       Calmodulin-binding protein 60 C.
FT                                /FTId=PRO_0000433047.
FT   REGION       10     89       Calmodulin-binding.
FT                                {ECO:0000250|UniProtKB:F4K2R6}.
FT   REGION      159    282       DNA-binding.
FT                                {ECO:0000250|UniProtKB:F4K2R6}.
FT   COMPBIAS     24     29       Poly-Gln. {ECO:0000255}.
FT   VAR_SEQ       1    307       Missing (in isoform 2).
FT                                /FTId=VSP_057663.
SQ   SEQUENCE   622 AA;  70200 MW;  011DFD90AC963F6B CRC64;
     MQTRYMERTN SMREKRKLEE DDNQQQQQQP ERKRPALASV IVEALKMDSL QRLCSSLEPI
     LRRVVSEEVE RALAKLGPAR LSERSSPKRI EGIGGRNLQL QFRSRLSVPL FTGGKIEGEQ
     GAAIHVVLLD MTTGHVLTVG PEASAKLDVV VLDGDFNTED DDGWSGEEFE GHLVKERQGK
     RPLLTGDVQV TLKEGVGTLG ELIFTDNSSW IRCRKFRLGL RVSSGYCEGM RVREAKTEAF
     TVKDHRGELY KKHYPPALDD EVWRLEKIGK DGAFHKKLNK AGIYNVKEFL RLMVKDSQKL
     RTILGSGMSN RMWETLAEHS KTCVLSEMLY VYYPEDSVGV VFNNIYEFSG LISGKQYYPA
     DSLSDNQKGY VDGLVRKAYE NWEQVIEYDS KSLMNFNQVS KTDDIDYSMP VSVPSQPSTS
     YSDVTVEAYN QSPASSFPGQ SQLADTTYMH FGNSSFAPQD QLVNNTHESQ SMINSNGGVR
     LALGPATGSQ NQEQLVHPPP EINSYNDWSN TCNRGVDGFL SEEEIRARSN EMLENDDMQQ
     LLRLFSMNGG DQQTPLNMGE DSFGFHSFGQ TSMADYEEDR SNSGKAVVGW LKIKAAMRWG
     FFIRRKAAQR RAQIVQLDED DE
//

If you have problems or comments...

PBIL Back to PBIL home page