(data stored in SCRATCH9089 zone)

SWISSPROT: NHAB_PASMU

ID   NHAB_PASMU              Reviewed;         513 AA.
AC   Q9CPJ1;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   11-DEC-2019, entry version 91.
DE   RecName: Full=Na(+)/H(+) antiporter NhaB {ECO:0000255|HAMAP-Rule:MF_01599};
DE   AltName: Full=Sodium/proton antiporter NhaB {ECO:0000255|HAMAP-Rule:MF_01599};
GN   Name=nhaB {ECO:0000255|HAMAP-Rule:MF_01599}; OrderedLocusNames=PM0047;
OS   Pasteurella multocida (strain Pm70).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Pasteurella.
OX   NCBI_TaxID=272843;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pm70;
RX   PubMed=11248100; DOI=10.1073/pnas.051634598;
RA   May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.;
RT   "Complete genomic sequence of Pasteurella multocida Pm70.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001).
CC   -!- FUNCTION: Na(+)/H(+) antiporter that extrudes sodium in exchange for
CC       external protons. {ECO:0000255|HAMAP-Rule:MF_01599}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01599}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01599}.
CC   -!- SIMILARITY: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter
CC       family. {ECO:0000255|HAMAP-Rule:MF_01599}.
DR   EMBL; AE004439; AAK02131.1; -; Genomic_DNA.
DR   RefSeq; WP_010906451.1; NC_002663.1.
DR   PRIDE; Q9CPJ1; -.
DR   EnsemblBacteria; AAK02131; AAK02131; PM0047.
DR   KEGG; pmu:PM0047; -.
DR   PATRIC; fig|272843.6.peg.48; -.
DR   eggNOG; ENOG4105DKR; Bacteria.
DR   eggNOG; COG3067; LUCA.
DR   HOGENOM; HOG000218133; -.
DR   KO; K03314; -.
DR   OMA; QFEMLAV; -.
DR   BioCyc; PMUL272843:G1FZ8-49-MONOMER; -.
DR   Proteomes; UP000000809; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR   HAMAP; MF_01599; NhaB; 1.
DR   InterPro; IPR004671; Na+/H+_antiporter_NhaB.
DR   PANTHER; PTHR43302:SF1; PTHR43302:SF1; 1.
DR   Pfam; PF06450; NhaB; 1.
DR   TIGRFAMs; TIGR00774; NhaB; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q9CPJ1.
DR   SWISS-2DPAGE; Q9CPJ1.
KW   Antiport; Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW   Reference proteome; Sodium; Sodium transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..513
FT                   /note="Na(+)/H(+) antiporter NhaB"
FT                   /id="PRO_0000333102"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
FT   TRANSMEM        197..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
FT   TRANSMEM        389..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
FT   TRANSMEM        447..467
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
FT   TRANSMEM        477..497
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01599"
SQ   SEQUENCE   513 AA;  56186 MW;  A4C34156D6B28426 CRC64;
     MSYTQAFLRN FLGTSPNWYK ITIVLFLIIN PIIFFFISPF IAGWLLVAEF ILTLAMALKC
     YPLQPGGLLA LEAVAIGMTH PEHVKAEIIA NFEVILLLIF MVAGIYFMKR LLLFVFTKLL
     LSIRSKMVLS LAFCLSAAFL SAFLDALTVV AVIISVGMGF YGVYHKVASG NNFNDSTDIT
     KDDKIGENKD TLEQFRAFLR SLMMHSCVGT ALGGVMTMVG EPQNLIIAEQ AKWAFGEFFL
     RMLPVTLPVL ICGLVTCFLV EKFGVFGYGA KLPRKVWGIL AKFDRNNQQK MSQQDRLKLF
     VQALIGIWLV VGLAFHLAAV GIIGLTVIIL ATSFCGVTSE HAIGKAFQES LPFTALLVVF
     FSVVAVIIDQ HLFAPIIQFV LAASEHTQLA LFYIFNGLLS AISDNVFVAT VYINETKAAL
     EAGLIAQPQY ELLAVAINTG TNLPSVATPN GQAAFLFLLT SSLAPLIRLS YGRMVYMALP
     YTIVLSCIGL LAVEYILPGA TNVLIQIGLL KPM
//

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