(data stored in SCRATCH9089 zone)

SWISSPROT: FADR_PASMU

ID   FADR_PASMU              Reviewed;         241 AA.
AC   Q9CPJ0;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   11-DEC-2019, entry version 114.
DE   RecName: Full=Fatty acid metabolism regulator protein {ECO:0000255|HAMAP-Rule:MF_00696};
GN   Name=fadR {ECO:0000255|HAMAP-Rule:MF_00696}; OrderedLocusNames=PM0048;
OS   Pasteurella multocida (strain Pm70).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Pasteurella.
OX   NCBI_TaxID=272843;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pm70;
RX   PubMed=11248100; DOI=10.1073/pnas.051634598;
RA   May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.;
RT   "Complete genomic sequence of Pasteurella multocida Pm70.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001).
CC   -!- FUNCTION: Multifunctional regulator of fatty acid metabolism.
CC       {ECO:0000255|HAMAP-Rule:MF_00696}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00696}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00696}.
DR   EMBL; AE004439; AAK02132.1; -; Genomic_DNA.
DR   RefSeq; WP_005724453.1; NC_002663.1.
DR   SMR; Q9CPJ0; -.
DR   EnsemblBacteria; AAK02132; AAK02132; PM0048.
DR   GeneID; 29388568; -.
DR   KEGG; pmu:PM0048; -.
DR   eggNOG; ENOG4105C05; Bacteria.
DR   eggNOG; COG2186; LUCA.
DR   HOGENOM; HOG000278467; -.
DR   KO; K03603; -.
DR   OMA; WETAGPN; -.
DR   BioCyc; PMUL272843:G1FZ8-50-MONOMER; -.
DR   Proteomes; UP000000809; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0019217; P:regulation of fatty acid metabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.20.120.530; -; 1.
DR   HAMAP; MF_00696; HTH_FadR; 1.
DR   InterPro; IPR014178; FA-response_TF_FadR.
DR   InterPro; IPR028374; FadR_C.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43537:SF10; PTHR43537:SF10; 1.
DR   Pfam; PF07840; FadR_C; 1.
DR   Pfam; PF00392; GntR; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF48008; SSF48008; 1.
DR   TIGRFAMs; TIGR02812; fadR_gamma; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q9CPJ0.
DR   SWISS-2DPAGE; Q9CPJ0.
KW   Activator; Cytoplasm; DNA-binding; Fatty acid metabolism; Lipid metabolism;
KW   Reference proteome; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..241
FT                   /note="Fatty acid metabolism regulator protein"
FT                   /id="PRO_0000050630"
FT   DOMAIN          11..79
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00696"
FT   DNA_BIND        39..58
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00696"
SQ   SEQUENCE   241 AA;  27339 MW;  60356B021F65C67E CRC64;
     MNNDQPLLKA QSPAGLAEEY IVRSIWNNHF PPGSDLPAER ELAEKIGVTR TTLREVLQRL
     ARDGWLNIQH GKPTKVNNIW ETSGLNILEV LVRLDSTKLP SFISNILSAR TNISAIYIQK
     AFKVEPQKSL EAFKDLDTLA DTAEAYTNFD YDLFRKLAFA SDNPVYGLIL NSLKGLYTRV
     GLFYFANPSA RELAKRFYLS LKTLCQTQQV NDVKECIRQY GKDSGVIWAN MQAYLPANFN
     E
//

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