(data stored in ACNUC7421 zone)

SWISSPROT: OADB1_SALTY

ID   OADB1_SALTY             Reviewed;         433 AA.
AC   Q8ZRY4;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   11-DEC-2019, entry version 91.
DE   RecName: Full=Oxaloacetate decarboxylase beta chain 1;
DE            EC=7.2.4.2;
GN   Name=oadB1; OrderedLocusNames=STM0054;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Catalyzes the decarboxylation of oxaloacetate coupled to
CC       Na(+) translocation. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) +
CC         pyruvate; Xref=Rhea:RHEA:57724, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:29101; EC=7.2.4.2;
CC   -!- COFACTOR:
CC       Name=Na(+); Xref=ChEBI:CHEBI:29101; Evidence={ECO:0000250};
CC   -!- SUBUNIT: Heterotrimer of an alpha, a beta and a gamma subunit.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GcdB/MmdB/OadB family. {ECO:0000305}.
DR   EMBL; AE006468; AAL19018.1; -; Genomic_DNA.
DR   RefSeq; NP_459059.1; NC_003197.2.
DR   RefSeq; WP_000444828.1; NC_003197.2.
DR   SMR; Q8ZRY4; -.
DR   PaxDb; Q8ZRY4; -.
DR   PRIDE; Q8ZRY4; -.
DR   EnsemblBacteria; AAL19018; AAL19018; STM0054.
DR   GeneID; 1251572; -.
DR   KEGG; stm:STM0054; -.
DR   PATRIC; fig|99287.12.peg.56; -.
DR   eggNOG; ENOG4105D9Q; Bacteria.
DR   eggNOG; COG1883; LUCA.
DR   HOGENOM; HOG000295684; -.
DR   KO; K20509; -.
DR   OMA; PMIADPK; -.
DR   PhylomeDB; Q8ZRY4; -.
DR   BioCyc; SENT99287:STM0054-MONOMER; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015451; F:decarboxylation-driven active transmembrane transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005661; OadB_MmdB.
DR   PANTHER; PTHR35806; PTHR35806; 1.
DR   Pfam; PF03977; OAD_beta; 1.
DR   PIRSF; PIRSF015658; MmdB_OadB; 1.
DR   TIGRFAMs; TIGR01109; Na_pump_decarbB; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q8ZRY4.
DR   SWISS-2DPAGE; Q8ZRY4.
KW   Cell membrane; Ion transport; Membrane; Reference proteome; Sodium;
KW   Sodium transport; Translocase; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..433
FT                   /note="Oxaloacetate decarboxylase beta chain 1"
FT                   /id="PRO_0000236039"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        266..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        340..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   433 AA;  44887 MW;  117DA49E85E01D42 CRC64;
     MESLNALLQG MGLMHLGAGQ AIMLLVSLLL LWLAIAKKFE PLLLLPIGFG GLLSNIPEAG
     MALTALESLL AHHDAGQLAV IAAKLNCAPD VHAIKEALAL ALPSVQGQME NLAVDMGYTP
     GVLALFYKVA IGSGVAPLVI FMGVGAMTDF GPLLANPRTL LLGAAAQFGI FATVLGALTL
     NYFGLISFTL PQAAAIGIIG GADGPTAIYL SGKLAPELLG AIAVAAYSYM ALVPLIQPPI
     MKALTSETER KIRMVQLRTV SKREKILFPV VLLMLVALLL PDAAPLLGMF CFGNLMRESG
     VVERLSDTVQ NGLINIVTIF LGLSVGAKLV ADKFLQPQTL GILLLGVIAF GIGTAAGVLM
     AKLLNLCSKN KINPLIGSAG VSAVPMAARV SNKVGLESDP QNFLLMHAMG PNVAGVIGSA
     IAAGVMLKYV LAM
//

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