(data stored in ACNUC7421 zone)

SWISSPROT: PHNR_SALTY

ID   PHNR_SALTY              Reviewed;         239 AA.
AC   Q7CR30; Q79BM3;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 102.
DE   RecName: Full=Putative transcriptional regulator of 2-aminoethylphosphonate degradation operons;
GN   Name=phnR; OrderedLocusNames=STM0430;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RA   Metcalf W.W., Jiang W., Wanner B.L.;
RT   "Molecular genetic analysis of the Salmonella typhimurium LT2 phnXWRSTUV
RT   locus required for 2-aminoethylphosphonate transport and metabolism.";
RL   Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [3]
RP   CLONING, AND INDUCTION.
RC   STRAIN=LT2;
RX   PubMed=7592415; DOI=10.1128/jb.177.22.6411-6421.1995;
RA   Jiang W., Metcalf W.W., Lee K.-S., Wanner B.L.;
RT   "Molecular cloning, mapping, and regulation of Pho regulon genes for
RT   phosphonate breakdown by the phosphonatase pathway of Salmonella
RT   typhimurium LT2.";
RL   J. Bacteriol. 177:6411-6421(1995).
CC   -!- INDUCTION: Induced when inorganic phosphate is limiting; this is
CC       controlled by PhoB. {ECO:0000269|PubMed:7592415}.
CC   -!- MISCELLANEOUS: Maps to a phosphate-starvation-inducible locus
CC       previously known as PsiC.
DR   EMBL; U69493; AAB39643.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL19384.1; -; Genomic_DNA.
DR   RefSeq; NP_459425.1; NC_003197.2.
DR   RefSeq; WP_000836268.1; NC_003197.2.
DR   SMR; Q7CR30; -.
DR   PaxDb; Q7CR30; -.
DR   PRIDE; Q7CR30; -.
DR   DNASU; 1251949; -.
DR   EnsemblBacteria; AAL19384; AAL19384; STM0430.
DR   GeneID; 1251949; -.
DR   KEGG; stm:STM0430; -.
DR   PATRIC; fig|99287.12.peg.459; -.
DR   eggNOG; ENOG4106S9K; Bacteria.
DR   eggNOG; COG2188; LUCA.
DR   HOGENOM; HOG000228717; -.
DR   OMA; NRHTVRS; -.
DR   PhylomeDB; Q7CR30; -.
DR   BioCyc; SENT99287:STM0430-MONOMER; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IBA:GO_Central.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.1410.10; -; 1.
DR   InterPro; IPR028978; Chorismate_lyase_/UTRA_dom_sf.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR017722; Tscrpt_reg_PhnR.
DR   InterPro; IPR011663; UTRA.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00392; GntR; 1.
DR   Pfam; PF07702; UTRA; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SMART; SM00866; UTRA; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF64288; SSF64288; 1.
DR   TIGRFAMs; TIGR03337; phnR; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   2: Evidence at transcript level;
DR   PRODOM; Q7CR30.
DR   SWISS-2DPAGE; Q7CR30.
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..239
FT                   /note="Putative transcriptional regulator of 2-
FT                   aminoethylphosphonate degradation operons"
FT                   /id="PRO_0000286734"
FT   DOMAIN          8..76
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   DNA_BIND        36..55
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
SQ   SEQUENCE   239 AA;  27482 MW;  006B79DE87B2C0A2 CRC64;
     MKSIPGDIPQ YLLIKAQLQA RIQSGALKSG DKLPSERELC AIFNTTRITI RESLAQLESS
     GLIWRADRRG WFVTPERLWL DPTQNTNFHK LCREQGREPK TALLSGVLTT VPVEVMEPLQ
     LQPFDQIYLL TRLRYADGRA VCYCENHCLP ARVPELLQYD LNGSLTEVYE SHYNLVYTSM
     HLSFYPTAMP AQAAQALGVM EGRPALLLRR LNYDQHGRVL DLDIEYWRHD SLRIEVDTH
//

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