(data stored in ACNUC7421 zone)

SWISSPROT: DBHB_SALTY

ID   DBHB_SALTY              Reviewed;          90 AA.
AC   P0A1R8; P05515;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   11-DEC-2019, entry version 79.
DE   RecName: Full=DNA-binding protein HU-beta;
DE   AltName: Full=HU-1;
DE   AltName: Full=NS1;
GN   Name=hupB; OrderedLocusNames=STM0451;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=3043381; DOI=10.1093/nar/16.14.7196;
RA   Marsh M., Hillyard D.R.;
RT   "Nucleotide sequence of the HU-1 gene of Salmonella typhimurium.";
RL   Nucleic Acids Res. 16:7196-7196(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
DR   EMBL; X07844; CAA30692.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL19406.1; -; Genomic_DNA.
DR   PIR; S01732; S01732.
DR   RefSeq; NP_459447.1; NC_003197.2.
DR   RefSeq; WP_001043544.1; NC_003197.2.
DR   SMR; P0A1R8; -.
DR   PaxDb; P0A1R8; -.
DR   PRIDE; P0A1R8; -.
DR   EnsemblBacteria; AAL19406; AAL19406; STM0451.
DR   GeneID; 1251971; -.
DR   KEGG; stm:STM0451; -.
DR   PATRIC; fig|99287.12.peg.483; -.
DR   eggNOG; ENOG4105K70; Bacteria.
DR   eggNOG; COG0776; LUCA.
DR   HOGENOM; HOG000043828; -.
DR   KO; K03530; -.
DR   OMA; RTGINPQ; -.
DR   PhylomeDB; P0A1R8; -.
DR   BioCyc; SENT99287:STM0451-MONOMER; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
DR   PRODOM; P0A1R8.
DR   SWISS-2DPAGE; P0A1R8.
KW   DNA condensation; DNA-binding; Reference proteome.
FT   CHAIN           1..90
FT                   /note="DNA-binding protein HU-beta"
FT                   /id="PRO_0000104971"
SQ   SEQUENCE   90 AA;  9240 MW;  846A3DACC622613D CRC64;
     MNKSQLIEKI AAGADISKAA AGRALDAIIA SVTESLKEGD DVALVGFGTF AVKERAARTG
     RNPQTGKEIT IAAAKVPSFR AGKALKDAVN
//

If you have problems or comments...

PBIL Back to PBIL home page