(data stored in ACNUC7421 zone)

SWISSPROT: Q75CV3_ASHGO

ID   Q75CV3_ASHGO            Unreviewed;       861 AA.
AC   Q75CV3;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 2.
DT   11-DEC-2019, entry version 106.
DE   SubName: Full=ACL187Wp {ECO:0000313|EMBL:AAS51041.2};
GN   ORFNames=AGOS_ACL187W {ECO:0000313|EMBL:AAS51041.2};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS51041.2, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS51041.2, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00704922}.
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DR   EMBL; AE016816; AAS51041.2; -; Genomic_DNA.
DR   RefSeq; NP_983217.2; NM_208570.2.
DR   STRING; 33169.AAS51041; -.
DR   EnsemblFungi; AAS51041; AAS51041; AGOS_ACL187W.
DR   GeneID; 4619337; -.
DR   KEGG; ago:AGOS_ACL187W; -.
DR   HOGENOM; HOG000204108; -.
DR   InParanoid; Q75CV3; -.
DR   KO; K14293; -.
DR   OMA; KNHLTSK; -.
DR   Proteomes; UP000000591; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0042564; C:NLS-dependent protein nuclear import complex; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0097718; F:disordered domain specific binding; IEA:EnsemblFungi.
DR   GO; GO:0061676; F:importin-alpha family protein binding; IEA:EnsemblFungi.
DR   GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR   GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR   GO; GO:0044877; F:protein-containing complex binding; IEA:EnsemblFungi.
DR   GO; GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IEA:EnsemblFungi.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; IEA:EnsemblFungi.
DR   GO; GO:0051292; P:nuclear pore complex assembly; IEA:EnsemblFungi.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IEA:EnsemblFungi.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   GO; GO:0006612; P:protein targeting to membrane; IEA:EnsemblFungi.
DR   GO; GO:0060188; P:regulation of protein desumoylation; IEA:EnsemblFungi.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527; PTHR10527; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   4: Predicted;
DR   PRODOM; Q75CV3.
DR   SWISS-2DPAGE; Q75CV3.
KW   Nucleus {ECO:0000256|SAAS:SAAS00704873};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591}.
FT   DOMAIN          25..106
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   861 AA;  94773 MW;  5E63A9277DB807D0 CRC64;
     MSAQEIAQLL SNTILSPDAG VRLQSETQLR KLSNDNFLQY AGTLSQLLAD ESVILEARIL
     AALTLKNELV SKDPVKGQQF AQRWLGLVDA ESRHHIKQFA LAALVDKQPR VANASAQLIA
     AIADIELPRD EWPDLMKILV ENTTQHQPEN VKRASLLVLG YICEGADLSN KALIAQSNNI
     LIAIVQGAQI SEPSKAVRLT ALNSLADSLA FIKNNMEREG ERNYLMQVVC EATQADDEEI
     QAAAFGCLCK IMAQFYFLMK PYMEQALYAL TISTMQSQNE KVASMAVEFW STICEEEIDI
     AYELSQFPES PLQSFNFALS SLQEVVPNLL VLLTKQNEDP EDDDWNLAMS AGACLQLFAQ
     NCGNYIVEPV LQYVEQNITS ENWRQREAAV MSFGSILDGP DKVQLVSLVH QALPPILNLI
     NDPVLQVKET VAWCIGRIAD LVVGAIDPQR HLSDVINACL LGLNDHPKVA TNCAWTIINL
     VEQLADNPGS PIYNYYPVLV DSLMKTANRP DNEHGVRASA FSALTTLVEF STDQVGESVT
     SISSYVLDKL GHTINIDEGQ LSTDDRQSLE ELQSNILTVL SASIRKNPQS VSAVSDMLMD
     LFLKLLSKKD SSYIEDDVFY VISSLATSMG KGFERYLETF SPYLVHALNQ VQSQVSVTAV
     GLIADISNSL EDDFKKFAPA FMNVLGSMIS SQDARMELKP AVLSVFGDIA SNIGDDFIPY
     LNQVMALCVA AQNSGPESAS LDALEYNVKV QEAVLDAYVG MVAGLHSQPD ALFQYAGTIF
     QFLSSFAENP ALSSEDTSAR SAVGIIGDIA SMFPDGRIKQ LYAQTWVTEF IKKTRSNPNF
     SQATKDTARW AREQQKHQLT L
//

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