(data stored in ACNUC7421 zone)

SWISSPROT: COQ10_ASHGO

ID   COQ10_ASHGO             Reviewed;         204 AA.
AC   Q75CC1;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 90.
DE   RecName: Full=Coenzyme Q-binding protein COQ10, mitochondrial;
DE   Flags: Precursor;
GN   Name=COQ10; OrderedLocusNames=ACL012W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Required for the function of coenzyme Q in the respiratory
CC       chain. May serve as a chaperone or may be involved in the transport of
CC       Q6 from its site of synthesis to the catalytic sites of the respiratory
CC       complexes (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with coenzyme Q. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COQ10 family. {ECO:0000305}.
DR   EMBL; AE016816; AAS51216.1; -; Genomic_DNA.
DR   RefSeq; NP_983392.1; NM_208745.1.
DR   STRING; 33169.AAS51216; -.
DR   PRIDE; Q75CC1; -.
DR   EnsemblFungi; AAS51216; AAS51216; AGOS_ACL012W.
DR   GeneID; 4619517; -.
DR   KEGG; ago:AGOS_ACL012W; -.
DR   HOGENOM; HOG000000776; -.
DR   InParanoid; Q75CC1; -.
DR   KO; K18588; -.
DR   OMA; EMEDYKH; -.
DR   Proteomes; UP000000591; Chromosome III.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0048039; F:ubiquinone binding; IBA:GO_Central.
DR   GO; GO:0045333; P:cellular respiration; IBA:GO_Central.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IBA:GO_Central.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR005031; COQ10_START.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   Pfam; PF03364; Polyketide_cyc; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q75CC1.
DR   SWISS-2DPAGE; Q75CC1.
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..24
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..204
FT                   /note="Coenzyme Q-binding protein COQ10, mitochondrial"
FT                   /id="PRO_0000227687"
SQ   SEQUENCE   204 AA;  23309 MW;  6691B8C53A8F6B8D CRC64;
     MLRCLISRPQ LLPTRLPLAT PSCVSRRTFL GFTGGDTKEQ RYILKRVFNA PLHYVYPAVS
     EVSLYKLFIP YCTDSFVNKR RPGDNMPTEA GLRVGFQQYD ETFVCRVDCT TLPGNQRSVV
     AESLAHHLFE TLHTQWLLSP HPTRPDASVV ELILRFKFKS QLYNSVSSIF GTRVTQVVMK
     AFEKRVFQLR KEAMDRPPTG DAGH
//

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