(data stored in ACNUC7421 zone)

SWISSPROT: Q75CF0_ASHGO

ID   Q75CF0_ASHGO            Unreviewed;      1377 AA.
AC   Q75CF0;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 97.
DE   SubName: Full=ACL004Wp {ECO:0000313|EMBL:AAS51224.1};
GN   ORFNames=AGOS_ACL004W {ECO:0000313|EMBL:AAS51224.1};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS51224.1, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS51224.1, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00810}.
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DR   EMBL; AE016816; AAS51224.1; -; Genomic_DNA.
DR   RefSeq; NP_983400.1; NM_208753.1.
DR   STRING; 33169.AAS51224; -.
DR   EnsemblFungi; AAS51224; AAS51224; AGOS_ACL004W.
DR   GeneID; 4619525; -.
DR   KEGG; ago:AGOS_ACL004W; -.
DR   HOGENOM; HOG000248545; -.
DR   InParanoid; Q75CF0; -.
DR   KO; K11644; -.
DR   OMA; GRDELCN; -.
DR   Proteomes; UP000000591; Chromosome III.
DR   GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR   GO; GO:0033698; C:Rpd3L complex; IEA:EnsemblFungi.
DR   GO; GO:0032221; C:Rpd3S complex; IEA:EnsemblFungi.
DR   GO; GO:0070822; C:Sin3-type complex; IBA:GO_Central.
DR   GO; GO:0042802; F:identical protein binding; IEA:EnsemblFungi.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:EnsemblFungi.
DR   GO; GO:0003714; F:transcription corepressor activity; IBA:GO_Central.
DR   GO; GO:0044804; P:autophagy of nucleus; IEA:EnsemblFungi.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:EnsemblFungi.
DR   GO; GO:0016575; P:histone deacetylation; IBA:GO_Central.
DR   GO; GO:0061188; P:negative regulation of chromatin silencing at rDNA; IEA:EnsemblFungi.
DR   GO; GO:0061186; P:negative regulation of chromatin silencing at silent mating-type cassette; IEA:EnsemblFungi.
DR   GO; GO:0031939; P:negative regulation of chromatin silencing at telomere; IEA:EnsemblFungi.
DR   GO; GO:0016479; P:negative regulation of transcription by RNA polymerase I; IEA:EnsemblFungi.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0051038; P:negative regulation of transcription involved in meiotic cell cycle; IEA:EnsemblFungi.
DR   GO; GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IEA:EnsemblFungi.
DR   GO; GO:0070550; P:rDNA condensation; IEA:EnsemblFungi.
DR   GO; GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IEA:EnsemblFungi.
DR   GO; GO:0000117; P:regulation of transcription involved in G2/M transition of mitotic cell cycle; IEA:EnsemblFungi.
DR   GO; GO:0061587; P:transfer RNA gene-mediated silencing; IEA:EnsemblFungi.
DR   Gene3D; 1.20.1160.11; -; 3.
DR   InterPro; IPR013194; HDAC_interact_dom.
DR   InterPro; IPR003822; PAH.
DR   InterPro; IPR036600; PAH_sf.
DR   InterPro; IPR039774; Sin3-like.
DR   InterPro; IPR031693; Sin3_C.
DR   PANTHER; PTHR12346; PTHR12346; 1.
DR   Pfam; PF02671; PAH; 3.
DR   Pfam; PF08295; Sin3_corepress; 1.
DR   Pfam; PF16879; Sin3a_C; 1.
DR   SMART; SM00761; HDAC_interact; 1.
DR   SUPFAM; SSF47762; SSF47762; 3.
DR   PROSITE; PS51477; PAH; 3.
PE   4: Predicted;
DR   PRODOM; Q75CF0.
DR   SWISS-2DPAGE; Q75CF0.
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00810};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591}.
FT   DOMAIN          583..684
FT                   /note="HDAC_interact"
FT                   /evidence="ECO:0000259|SMART:SM00761"
FT   REGION          1..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          108..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          873..904
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          921..944
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1354..1377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        882..904
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1377 AA;  154255 MW;  E8765269DBBB1E6B CRC64;
     MSQSWSQHHQ VDHAGSGRPV GQAGPGPAGG TPQMGGGAGL LPGRRGSEGL KTHYTLPSIS
     AAGLPGAGEP HGGSRLPPMQ NALGVGGGGP GSIANGFAVG RLEGAVPVSG TGGPGSPGPQ
     VPAQDGSAYR PLNVKDALSY LEQVKFQFSS RPDVYNHFLD IMKDFKSQAI DTPGVIERVS
     TLFHGYPALI QGFNTFLPHG YNIECPSDPN DPIKVTTPFG TIGEIPITGA GGNHAHGANT
     EPRLQSTQNV PTVYRSAEGS PAAIATPATT QEQYGTGPKK AGDVEFSHAI SYVNKIKTRF
     AEQPDIYKHF LEILQTYQRE QKPINEVYAQ VTVLFQNAPD LLDDFKKFLP DSSAPQLQSH
     QQINGAMVAP GFGHAQSGLQ QALPGTQPLM HQQNLPPLGN FSTPGDHHPM SLPSVQGPNV
     GLSQGQSGHI VTQGVSNQHI PVSDLRGAPD ASFRASEYNQ VQDVQYMEPT VRPEIDLDPS
     LVPVIPEPIK PLEDELNLVE EATFFDKAKK FIGNKQIYTE FLKILNLYSQ DLLEKEKLVE
     DVSHYLSGSP ELFDWFKSFV GYQERPKHIE NVIHEKHRLD LDLCEACGPS YKRLPKADTF
     MPCSGRDEMC WEVLNDEWVG HPVWASEDSG FIAHRKNQYE DTLFKIEEER HEYDFYIEAN
     LRTIQTLETI ANKIANMTPE EKAAFKLPPG LGHTSVTIYK KVIRKVYDKD RGFEIIDALH
     EHPAITVPLV LKRLKQKDEE WRRAQREWNK VWRELEQKVF YKSLDHLGLT FKQADKKLLT
     AKQLISEISS IKVDQSNKRI HPLTPKAKSQ LSYDFKEPEV FQDILSLVMV FLANNNTYSP
     SDNERLKDFF KGFISLFFSY PLHEIEEGLL KRSSQNGTIS HGDDTRKSKE DPKTEKHSAR
     KRVRDDTEHL LRDILYRNKQ QKVNKGPQND QSSEEFEKES DIEEKEIVRQ EAKKPWLLGS
     IVDEADNHGH VSDRVTFNMF ANTNIYVFFR HLTTMYERLV EVKKINGEVT KEISNRKVVQ
     FAKDLNLIST QLTDMGLDFK GADAYEELLR LSRSLISGEL EHQWFEESLR QAYKNKAFKL
     YTIDKVIQAL VKHAHTILMD HKTVEIMLLF DNDRTSTSTS TKDQILYRLQ VRSNMSNIEN
     MFRIEYNTTT SHASIQFVAV EDLTLDEPKS LRDKWQYYLT SYSLSHPTEG ISHDNLRTPF
     LEKIIERDEG YIDDGDERYS PEGVASSNMK VKIDPLTYSM EVEPGCHDIF SRKSVNKFPT
     RVDVKKKKSA ELKLVLEGFL NGERGWKRGL TTKRTAEAER RLEYVKNNGT LDDYAEEIST
     DTKAALSTTT DTAGNVSTAS FSSQTAANAA ISASSPESAL QSNNGNSEVT SPIANDI
//

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