(data stored in ACNUC7421 zone)

SWISSPROT: NOP9_ASHGO

ID   NOP9_ASHGO              Reviewed;         678 AA.
AC   Q75C70;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 2.
DT   11-DEC-2019, entry version 86.
DE   RecName: Full=Nucleolar protein 9;
DE   AltName: Full=Pumilio domain-containing protein NOP9;
GN   Name=NOP9; OrderedLocusNames=ACR046W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: RNA-binding nucleolar protein required for pre-rRNA
CC       processing. Involved in production of 18S rRNA and assembly of small
CC       ribosomal subunit (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP9 family. {ECO:0000305}.
DR   EMBL; AE016816; AAS51273.2; -; Genomic_DNA.
DR   RefSeq; NP_983449.2; NM_208802.2.
DR   SMR; Q75C70; -.
DR   STRING; 33169.AAS51273; -.
DR   PRIDE; Q75C70; -.
DR   EnsemblFungi; AAS51273; AAS51273; AGOS_ACR046W.
DR   GeneID; 4619574; -.
DR   KEGG; ago:AGOS_ACR046W; -.
DR   HOGENOM; HOG000248568; -.
DR   InParanoid; Q75C70; -.
DR   KO; K14790; -.
DR   OMA; HFQGQLQ; -.
DR   Proteomes; UP000000591; Chromosome III.
DR   GO; GO:0030686; C:90S preribosome; IEA:EnsemblFungi.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030688; C:preribosome, small subunit precursor; IEA:EnsemblFungi.
DR   GO; GO:0003723; F:RNA binding; IEA:EnsemblFungi.
DR   GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000056; P:ribosomal small subunit export from nucleus; IEA:EnsemblFungi.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040000; NOP9.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13102; PTHR13102; 1.
DR   Pfam; PF00806; PUF; 1.
DR   SMART; SM00025; Pumilio; 8.
DR   SUPFAM; SSF48371; SSF48371; 2.
PE   3: Inferred from homology;
DR   PRODOM; Q75C70.
DR   SWISS-2DPAGE; Q75C70.
KW   Nucleus; Reference proteome; Repeat; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..678
FT                   /note="Nucleolar protein 9"
FT                   /id="PRO_0000407795"
FT   REPEAT          91..126
FT                   /note="Pumilio 1"
FT   REPEAT          127..162
FT                   /note="Pumilio 2"
FT   REPEAT          189..224
FT                   /note="Pumilio 3"
FT   REPEAT          288..326
FT                   /note="Pumilio 4"
FT   REPEAT          338..373
FT                   /note="Pumilio 5"
FT   REPEAT          375..411
FT                   /note="Pumilio 6"
FT   REPEAT          515..552
FT                   /note="Pumilio 7"
FT   REPEAT          553..591
FT                   /note="Pumilio 8"
SQ   SEQUENCE   678 AA;  78248 MW;  806BB82538A6C4F6 CRC64;
     MAKQRGRKLL QKQNKDDFKH SLDQERHEEE VIQVPVDKAP APISADGPNT FFGTLDTQEL
     EYFKRAESTM AVDTFESADE KYQFINSVIE ESKGKELKLA TSQICSKLME RIILAADDQQ
     LKAIFQGING FFVNLSYNKY ASHVVETLLV RSAALIEKEL LTPVFEAELD GDEQVYASME
     NMFLFMLNEL KPHMKMMINH QYASHVFRLL ILVLSAKKLP KSTQSNSALR SKKSKIARKM
     VDLKDNADFD RTYRTPDSFK LELKGILVML YKQFTNGIEP GTKHSEVNIA CVTKFREYCV
     DKVASPVIQL IIQVEGIFDR DRSFWNLVFS NTEQNDPKEE SFMEYLLSDS VGSHFLQAVI
     GFARTKQVER LYKLYMQDRI VKLAKRDTTG AFVIMSLLQN LGSKEVKSIL DDLVPELSIL
     LNSNLDFGSE IIEASIRQGD YKKTEIVEQL GKKYYPADSE SKNILESCLQ LASSTLGNTK
     DDWPTADERR RALFLEKLIN FDDYFLEIAV ESLLNLPEER IMQMCYHGVF SHVVEHVLQA
     KRVETVKRKL LLNILYKDAV NLACNAYGSH IMDKLWEFTA KLTLYKERIA NLLLEEADKV
     KNSIYGRQVW KNWHLELYVR KRFDWRKKVK EQELEVFPDS KPLQPKQKES IPAKRSAPSN
     NQRPGSLNKK RNAEKHHT
//

If you have problems or comments...

PBIL Back to PBIL home page