(data stored in ACNUC7421 zone)

SWISSPROT: Q75C15_ASHGO

ID   Q75C15_ASHGO            Unreviewed;       840 AA.
AC   Q75C15;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 2.
DT   11-DEC-2019, entry version 106.
DE   RecName: Full=Replication factor C subunit 1 {ECO:0000256|PIRNR:PIRNR036578};
GN   ORFNames=AGOS_ACR102W {ECO:0000313|EMBL:AAS51328.2};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS51328.2, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS51328.2, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036578}.
CC   -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC       {ECO:0000256|PIRNR:PIRNR036578}.
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DR   EMBL; AE016816; AAS51328.2; -; Genomic_DNA.
DR   RefSeq; NP_983504.2; NM_208857.2.
DR   STRING; 33169.AAS51328; -.
DR   EnsemblFungi; AAS51328; AAS51328; AGOS_ACR102W.
DR   GeneID; 4619634; -.
DR   KEGG; ago:AGOS_ACR102W; -.
DR   HOGENOM; HOG000164552; -.
DR   InParanoid; Q75C15; -.
DR   KO; K10754; -.
DR   OMA; HVVLKPW; -.
DR   Proteomes; UP000000591; Chromosome III.
DR   GO; GO:0005663; C:DNA replication factor C complex; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006272; P:leading strand elongation; IEA:EnsemblFungi.
DR   GO; GO:0006298; P:mismatch repair; IEA:EnsemblFungi.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:EnsemblFungi.
DR   Gene3D; 3.40.50.10190; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012178; RFC1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF00533; BRCT; 1.
DR   Pfam; PF08519; RFC1; 1.
DR   PIRSF; PIRSF036578; RFC1; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00292; BRCT; 1.
DR   SUPFAM; SSF48019; SSF48019; 1.
DR   SUPFAM; SSF52113; SSF52113; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50172; BRCT; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q75C15.
DR   SWISS-2DPAGE; Q75C15.
KW   ATP-binding {ECO:0000256|PIRNR:PIRNR036578};
KW   DNA replication {ECO:0000256|PIRNR:PIRNR036578};
KW   Nucleotide-binding {ECO:0000256|PIRNR:PIRNR036578};
KW   Nucleus {ECO:0000256|PIRNR:PIRNR036578};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591}.
FT   DOMAIN          142..219
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   REGION          1..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          253..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          773..840
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..36
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        55..74
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        785..799
FT                   /note="Acidic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        800..824
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        825..840
FT                   /note="Basic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   840 AA;  91918 MW;  20CB3020D5B07675 CRC64;
     MVDVREFFKA NSGNKPSAKG PPRKKAKIEE AKLPKGDAAS PIDVDLDDDD LEGLLEAKGE
     EKVVKREERP AVKKQPKQGI QSAGGVGSGR ASAAPAGNAQ EILAALPSVD LDSVHVKEGA
     NFGFGGSGES GGDANADDFA QGAPNCLLGL TMVFTGVLPN IDRPAAEALA KKYGARVTKS
     ISSKTSVVVL GDEAGPKKLE KIRQLGIKAI DENGFRQLIN AMPAEGGSGV AAERARQQLK
     KQEEDVLREA ETLARQEKER AASRASNAPG GHAAPRESDQ LWTVKYAPTS LSQICGNKSS
     VGKLHKWLSE WDNNQRNGFK TPGRDGTGIY RAAMLYGPPG IGKTTAAHLV ANELGYDVLE
     QNASDVRSKK LLNEGIKNAL DNTSVIGYFN KKEHRNSRKF VIIMDEVDGM SGGDRGGVGQ
     MAQFCRKTSS PLILICNERT LPKMRPFDRV VCDIQFRRPD AQSMKARLMT IAVREGFKLD
     PTVVDQLVAA TRGDIRQIIN LLSTISTTTK SIGHDNARQI SAAWEKNIAL KPYDITHKLF
     EGRNYSDAGA QSFPLYKKME LYFDDFDFTP LMVQENYLST RPTNLSPGQS HLQAAAAAAD
     SISEGDLVDR KIRSGEQLWS LLPFHAVMSS VRPASLVSGQ MAGRINFTSW LGQNSKRGKY
     YRLLQELHYH TRLRTSASKV SFRLDYLTTL KRRLLSPLVE NGGEAIPNII ETMDSYYLTK
     EDWDVVMDFM LGYENTEAAL KKISTSDKRA FTTMYNKTTH PVAINRTGTT IAISGKSGND
     KPDFEEVVDA DDEVPPDNDD AKNDESADLK KDKLIKERKP RARKATGSSK APAKRKKVSK
//

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