(data stored in ACNUC7421 zone)

SWISSPROT: Q758H4_ASHGO

ID   Q758H4_ASHGO            Unreviewed;       723 AA.
AC   Q758H4;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 83.
DE   RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN   ORFNames=AGOS_AEL212W {ECO:0000313|EMBL:AAS52473.1};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS52473.1, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS52473.1, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC       cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|RuleBase:RU365057}.
CC   -!- SIMILARITY: Belongs to the SDA1 family.
CC       {ECO:0000256|RuleBase:RU365057}.
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DR   EMBL; AE016818; AAS52473.1; -; Genomic_DNA.
DR   RefSeq; NP_984649.1; NM_210002.1.
DR   STRING; 33169.AAS52473; -.
DR   EnsemblFungi; AAS52473; AAS52473; AGOS_AEL212W.
DR   GeneID; 4620831; -.
DR   KEGG; ago:AGOS_AEL212W; -.
DR   HOGENOM; HOG000204601; -.
DR   InParanoid; Q758H4; -.
DR   KO; K14856; -.
DR   OMA; AQVAQCY; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:GO_Central.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR   GO; GO:0007089; P:traversing start control point of mitotic cell cycle; IEA:EnsemblFungi.
DR   InterPro; IPR027312; Sda1.
DR   InterPro; IPR007949; SDA1_dom.
DR   InterPro; IPR012977; Uncharacterised_NUC130/133_N.
DR   PANTHER; PTHR12730; PTHR12730; 1.
DR   Pfam; PF08158; NUC130_3NT; 1.
DR   Pfam; PF05285; SDA1; 2.
PE   3: Inferred from homology;
DR   PRODOM; Q758H4.
DR   SWISS-2DPAGE; Q758H4.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|RuleBase:RU365057};
KW   Protein transport {ECO:0000256|RuleBase:RU365057};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591};
KW   Ribosome biogenesis {ECO:0000256|RuleBase:RU365057};
KW   Transport {ECO:0000256|RuleBase:RU365057}.
FT   DOMAIN          79..130
FT                   /note="NUC130_3NT"
FT                   /evidence="ECO:0000259|Pfam:PF08158"
FT   DOMAIN          445..581
FT                   /note="SDA1"
FT                   /evidence="ECO:0000259|Pfam:PF05285"
FT   DOMAIN          592..721
FT                   /note="SDA1"
FT                   /evidence="ECO:0000259|Pfam:PF05285"
FT   REGION          534..595
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          641..707
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          283..310
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        643..685
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   723 AA;  80829 MW;  F7B34208C0CE44CE CRC64;
     MVKKSRAAIL PTNVILLQNL VKRDPESYRE EFLQQYSHYE SLRDIFMMNS TTQDASSAGG
     SGSFADDESV GEFAELIGFV SQVCSCYPKE TAGFPAELKQ LLLEHHRALP FQVKEKIIAS
     LTMLRNKDVI TPDMLIQTLF PLLVAYSSTQ GSNIGLNSHA KALRKTVYGN VVSLLKNCNT
     GSKNQKLNRS TQAICFNLLE QPDSQGLWAT RLTRELWRRG IWDDSRAVEI MTQAALHDDV
     KIAASGVLFF LDADREREEN FEDKSDDDDV VDMQSLRHKL KINKKSSKRG KKLENAVKQV
     KKKSNSANDQ AYLNFSAIHL LRDPQGFAEK LFSKHMSGKG GTKFSLEQKI SLMQLTSRMI
     GTHKLLVLGI YSYFLKYLTP KQTDVTKILA TAAQSCHDLV PPEYLSVVVR KIADEFVSDG
     VSSEVCAAGL NSIREICSRA PLALDETLLR DLVEYKSSKA KGVSMAAKGL LALYREVAPE
     MLQRKDRGKL ASIELQQQRA AAAQPRRPQF GADSGVSGIP GLELLAEWER TQDRPAADDD
     DANWEVASSD DDVDGEWVTV QSDRDYDVDL SDSDLDLDDD EAAPAPAPAP AAPELAASRI
     LTPADFAKLQ ELRTERGVAK LLGVRNEDLV DSDALVGPVK YKQNKQERME RVLEGREGRD
     KFGSRKQKRG EQGRSTTNRE KQRKKNFVMM IHKRGVQGKQ KMSLRDKQKV LRAHITKQKK
     KGH
//

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