(data stored in ACNUC7421 zone)

SWISSPROT: SNU13_ASHGO

ID   SNU13_ASHGO             Reviewed;         127 AA.
AC   Q757T2;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 85.
DE   RecName: Full=13 kDa ribonucleoprotein-associated protein;
GN   Name=SNU13; OrderedLocusNames=AEL070W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Common component of the spliceosome and rRNA processing
CC       machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP
CC       particle, required for splicing of pre-mRNA. In association with box
CC       C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and
CC       site-specific 2'-O-methylation of substrate RNAs. Essential for the
CC       accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the U3 snoRNP particle. Binds to the C'/D and B/C
CC       motifs in U3 snoRNA. Component of the 25S U4/U6.U5 tri-snRNP particle,
CC       a subcomplex of the spliceosome. Binds to the 5' stem-loop of U4 snRNA
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC       {ECO:0000305}.
DR   EMBL; AE016818; AAS52615.1; -; Genomic_DNA.
DR   RefSeq; NP_984791.1; NM_210145.1.
DR   SMR; Q757T2; -.
DR   STRING; 33169.AAS52615; -.
DR   PRIDE; Q757T2; -.
DR   EnsemblFungi; AAS52615; AAS52615; AGOS_AEL070W.
DR   GeneID; 4620983; -.
DR   KEGG; ago:AGOS_AEL070W; -.
DR   HOGENOM; HOG000055226; -.
DR   InParanoid; Q757T2; -.
DR   KO; K12845; -.
DR   OMA; KPFYVRF; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0031428; C:box C/D snoRNP complex; IBA:GO_Central.
DR   GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   InterPro; IPR002415; H/ACA_rnp_Nhp2_euk.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
DR   InterPro; IPR018492; Ribosomal_L7Ae/L8/Nhp2.
DR   InterPro; IPR004037; Ribosomal_L7Ae_CS.
DR   Pfam; PF01248; Ribosomal_L7Ae; 1.
DR   PRINTS; PR00881; L7ARS6FAMILY.
DR   PRINTS; PR00883; NUCLEARHMG.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   PROSITE; PS01082; RIBOSOMAL_L7AE; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q757T2.
DR   SWISS-2DPAGE; Q757T2.
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Ribonucleoprotein; Ribosome biogenesis; RNA-binding; rRNA processing;
KW   Spliceosome.
FT   CHAIN           1..127
FT                   /note="13 kDa ribonucleoprotein-associated protein"
FT                   /id="PRO_0000290656"
SQ   SEQUENCE   127 AA;  13706 MW;  B2B5A04E0656C87E CRC64;
     MSSTPNPKAF PLADAALTQQ ILDVVQQASN MRQLKKGANE ATKTLNRGIS EFIIMAADCE
     PIEILLHLPL LCEDKNVPYV FVPSRVALGR ACGVSRPVIA ASITTNDASA IKSQIYAVKD
     KIETLLI
//

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