(data stored in ACNUC7421 zone)

SWISSPROT: MAF1_ASHGO

ID   MAF1_ASHGO              Reviewed;         397 AA.
AC   Q757K3;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 74.
DE   RecName: Full=Repressor of RNA polymerase III transcription MAF1;
GN   Name=MAF1; OrderedLocusNames=AER009C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Mediator of diverse signals that repress RNA polymerase III
CC       transcription. Inhibits the de novo assembly of TFIIIB onto DNA (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MAF1 family. {ECO:0000305}.
DR   EMBL; AE016818; AAS52693.1; -; Genomic_DNA.
DR   RefSeq; NP_984869.1; NM_210223.1.
DR   SMR; Q757K3; -.
DR   STRING; 33169.AAS52693; -.
DR   EnsemblFungi; AAS52693; AAS52693; AGOS_AER009C.
DR   GeneID; 4621068; -.
DR   KEGG; ago:AGOS_AER009C; -.
DR   HOGENOM; HOG000065964; -.
DR   InParanoid; Q757K3; -.
DR   OMA; CDIFTTK; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000994; F:RNA polymerase III core binding; IBA:GO_Central.
DR   GO; GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IBA:GO_Central.
DR   GO; GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IBA:GO_Central.
DR   GO; GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IBA:GO_Central.
DR   GO; GO:0016480; P:negative regulation of transcription by RNA polymerase III; IBA:GO_Central.
DR   GO; GO:0061587; P:transfer RNA gene-mediated silencing; IEA:EnsemblFungi.
DR   Gene3D; 3.40.1000.50; -; 1.
DR   InterPro; IPR015257; Maf1.
DR   InterPro; IPR038564; Maf1_sf.
DR   PANTHER; PTHR22504; PTHR22504; 1.
DR   Pfam; PF09174; Maf1; 1.
DR   PIRSF; PIRSF037240; RNA_polIII_Trep_MAF1; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q757K3.
DR   SWISS-2DPAGE; Q757K3.
KW   Nucleus; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..397
FT                   /note="Repressor of RNA polymerase III transcription MAF1"
FT                   /id="PRO_0000213970"
SQ   SEQUENCE   397 AA;  45029 MW;  D9C40DF684B55FDC CRC64;
     MKFIDELDLE LVNQTLNFET SESKISGGCD IFTTKPVASD KKLYKTIDRH LESLLQENES
     YNAAIQQQIE LENKRRDPKQ AGSDCAEPAE DSPTRNANSF WEQKRRMSVS ESPRADTSPL
     FKSQKLNDQQ LKELVSHPLE VPGCKSPSNE TSARGVLRRS TSAGSFENNA GSAEQQKRRT
     SSIGSAANGT KSPILRRSSF NRETINIGPF GPISETASRR TFAYLIGILN ASYPDHDFAS
     LKPTDFVKSS RKQLVSKFEN SIIALGKQPQ EWIWETINAH MDLADCVFYQ YNPQESFLDD
     EPGHLWSLMW FMFNKKRKRV AYFYLSAFRV KNPPSTGGSV ALDEYYDSNS KPELREKRRR
     LTIEHETNDF EGEYDLTYTS SGDGAVEDED EDMNDAD
//

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