(data stored in ACNUC7421 zone)

SWISSPROT: COX9_ASHGO

ID   COX9_ASHGO              Reviewed;          60 AA.
AC   Q757F0;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   11-DEC-2019, entry version 90.
DE   RecName: Full=Cytochrome c oxidase subunit 7A;
DE            EC=1.9.3.1;
DE   AltName: Full=Cytochrome c oxidase polypeptide VIIA;
DE   Flags: Precursor;
GN   Name=COX9; OrderedLocusNames=AER063W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: This small integral protein plays a role in holoenzyme
CC       assembly or stability. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=4 [Fe(II)cytochrome c] + 4 H(+) + O2 = 4 [Fe(III)cytochrome c]
CC         + 2 H2O; Xref=Rhea:RHEA:11436, Rhea:RHEA-COMP:10350, Rhea:RHEA-
CC         COMP:14399, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379,
CC         ChEBI:CHEBI:29033, ChEBI:CHEBI:29034; EC=1.9.3.1;
CC   -!- SUBUNIT: Composed of at least 11 subunits. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}.
DR   EMBL; AE016818; AAS52747.1; -; Genomic_DNA.
DR   RefSeq; NP_984923.1; NM_210277.1.
DR   STRING; 33169.AAS52747; -.
DR   EnsemblFungi; AAS52747; AAS52747; AGOS_AER063W.
DR   GeneID; 4621126; -.
DR   KEGG; ago:AGOS_AER063W; -.
DR   HOGENOM; HOG000199609; -.
DR   InParanoid; Q757F0; -.
DR   KO; K02269; -.
DR   OMA; GYAFWYG; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005746; C:mitochondrial respirasome; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IBA:GO_Central.
DR   InterPro; IPR014368; Cyt_c_oxidase_su7a_fun.
DR   PANTHER; PTHR28264; PTHR28264; 1.
DR   PIRSF; PIRSF000283; COX9; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q757F0.
DR   SWISS-2DPAGE; Q757F0.
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..57
FT                   /note="Cytochrome c oxidase subunit 7A"
FT                   /id="PRO_0000041763"
FT   PROPEP          58..60
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000041764"
FT   TRANSMEM        19..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   60 AA;  6714 MW;  7089BF0AA36815B6 CRC64;
     MSAIAPITGS LKKRIMKDIA VGMGLGTVLG SYWWWGFHKP KIAARENYYT QLAEQKAAEE
//

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