(data stored in ACNUC7421 zone)

SWISSPROT: PXR1_ASHGO

ID   PXR1_ASHGO              Reviewed;         335 AA.
AC   Q751P0;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 73.
DE   RecName: Full=Protein PXR1;
DE   AltName: Full=PinX1-related protein 1;
GN   Name=PXR1; OrderedLocusNames=AGL350C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in rRNA-processing at A0, A1 and A2 sites and
CC       regulates negatively telomerase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PINX1 family. {ECO:0000305}.
DR   EMBL; AE016820; AAS54141.1; -; Genomic_DNA.
DR   RefSeq; NP_986317.1; NM_211379.1.
DR   STRING; 33169.AAS54141; -.
DR   EnsemblFungi; AAS54141; AAS54141; AGOS_AGL350C.
DR   GeneID; 4622610; -.
DR   KEGG; ago:AGOS_AGL350C; -.
DR   HOGENOM; HOG000048630; -.
DR   InParanoid; Q751P0; -.
DR   KO; K11135; -.
DR   OMA; DPNNTKW; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR000467; G_patch_dom.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q751P0.
DR   SWISS-2DPAGE; Q751P0.
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000305"
FT   CHAIN           2..335
FT                   /note="Protein PXR1"
FT                   /id="PRO_0000324877"
FT   DOMAIN          25..71
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   COMPBIAS        161..278
FT                   /note="Lys-rich"
SQ   SEQUENCE   335 AA;  38534 MW;  ECFD2599FE77C1C1 CRC64;
     MGLAATKTKQ RFGLDPRNTT WSNDKSRFGH KYLEKLGWEP GKGLGHASHA MSTHIKVTIK
     DDTMGLGAKL KKKEKKDEFD SGECAGLDVF QRILGRLNGK EEVIADELEK QRKENIINGK
     WGIHFVKGEV LSSTWDADTM QLKSYSYDKK EITADDAEDA KVSGKHRDRK SRAKREKSNN
     AALKEKCRDI DRTRKSKRKE KEQEKEKNRE KKHNGKEHKE KEHKEKKDKK DKKEKKEKKE
     KKEKKEKKHK EKSNKRLRSS DSIDDPEATK PSKKSKTKAA DSDNVTRDSM LQPRASAASP
     PPTISTRLSV RSKWIRQKRA AVMDPKALNE IFMVT
//

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