(data stored in ACNUC7421 zone)

SWISSPROT: ELOC_ASHGO

ID   ELOC_ASHGO              Reviewed;         100 AA.
AC   Q751F9;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 90.
DE   RecName: Full=Elongin-C;
GN   Name=ELC1; OrderedLocusNames=AGL253C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Prevents degradation of interacting proteins by the
CC       proteasome. {ECO:0000250}.
CC   -!- SUBUNIT: Forms a complex with F-box protein ELA1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SKP1 family. {ECO:0000305}.
DR   EMBL; AE016820; AAS54238.1; -; Genomic_DNA.
DR   RefSeq; NP_986414.1; NM_211476.1.
DR   SMR; Q751F9; -.
DR   STRING; 33169.AAS54238; -.
DR   EnsemblFungi; AAS54238; AAS54238; AGOS_AGL253C.
DR   GeneID; 4622707; -.
DR   KEGG; ago:AGOS_AGL253C; -.
DR   HOGENOM; HOG000216525; -.
DR   InParanoid; Q751F9; -.
DR   KO; K03872; -.
DR   OMA; YFHYWYR; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:EnsemblFungi.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0070449; C:elongin complex; IBA:GO_Central.
DR   GO; GO:0000113; C:nucleotide-excision repair factor 4 complex; IEA:EnsemblFungi.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:EnsemblFungi.
DR   GO; GO:0070911; P:global genome nucleotide-excision repair; IEA:EnsemblFungi.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IBA:GO_Central.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   InterPro; IPR039948; ELC1.
DR   InterPro; IPR001232; SKP1-like.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR016073; Skp1_comp_POZ.
DR   PANTHER; PTHR20648; PTHR20648; 1.
DR   Pfam; PF03931; Skp1_POZ; 1.
DR   SMART; SM00512; Skp1; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q751F9.
DR   SWISS-2DPAGE; Q751F9.
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..100
FT                   /note="Elongin-C"
FT                   /id="PRO_0000239643"
SQ   SEQUENCE   100 AA;  11204 MW;  A6F1AC215D285A01 CRC64;
     MTPTSHVTLV SSDGKSFEVP RERAMLSPTL AKMLDSSFAE AKEAKVTLPT IESSMLAKVV
     EYLEYLEEYK HKDDGEDIPQ FEVPPEISLE LLLAADYLQI
//

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